Nam Le

Bao-Ngoc Dao, Quang Nguyen, Luyen Ngo Dinh et al.

Memory-based approaches have shown strong performance in Continual Relation Extraction (CRE). However, storing examples from previous tasks increases memory usage and raises privacy concerns. Recently, prompt-based methods have emerged as a promising alternative, as they do not rely on storing past samples. Despite this progress, current prompt-based techniques face several core challenges in CRE, particularly in accurately identifying task identities and mitigating catastrophic forgetting. Existing prompt selection strategies often suffer from inaccuracies, lack robust mechanisms to prevent forgetting in shared parameters, and struggle to handle both cross-task and within-task variations. In this paper, we propose WAVE++, a novel approach inspired by the connection between prefix-tuning and mixture of experts. Specifically, we introduce task-specific prompt pools that enhance flexibility and adaptability across diverse tasks while avoiding boundary-spanning risks; this design more effectively captures variations within each task and across tasks. To further refine relation classification, we incorporate label descriptions that provide richer, more global context, enabling the model to better distinguish among different relations. We also propose a training-free mechanism to improve task prediction during inference. Moreover, we integrate a generative model to consolidate prior knowledge within the shared parameters, thereby removing the need for explicit data storage. Extensive experiments demonstrate that WAVE++ outperforms state-of-the-art prompt-based and rehearsal-based methods, offering a more robust solution for continual relation extraction. Our code is publicly available at https://github.com/PiDinosauR2804/WAVE-CRE-PLUS-PLUS.

Nam H. Le, Patrick Erikson, Yanbo Zhang et al.

Guiding biological systems toward desired states, such as morphogenetic outcomes, remains a fundamental challenge with far-reaching implications for medicine and synthetic biology. While large language models (LLMs) have enabled natural language as an interface for interpretable control in AI systems, their use as mediators for steering biological or cellular dynamics remains largely unexplored. In this work, we present a functional pipeline that translates natural language prompts into spatial vector fields capable of directing simulated cellular collectives. Our approach combines a large language model with an evolvable neural controller (Prompt-to-Intervention, or P2I), optimized via evolutionary strategies to generate behaviors such as clustering or scattering in a simulated 2D environment. We demonstrate that even with constrained vocabulary and simplified cell models, evolved P2I networks can successfully align cellular dynamics with user-defined goals expressed in plain language. This work offers a complete loop from language input to simulated bioelectric-like intervention to behavioral output, providing a foundation for future systems capable of natural language-driven cellular control.

Nam Le

This paper presents a technique called evolving self-supervised neural networks - neural networks that can teach themselves, intrinsically motivated, without external supervision or reward. The proposed method presents some sort-of paradigm shift, and differs greatly from both traditional gradient-based learning and evolutionary algorithms in that it combines the metaphor of evolution and learning, more specifically self-learning, together, rather than treating these phenomena alternatively. I simulate a multi-agent system in which neural networks are used to control autonomous foraging agents with little domain knowledge. Experimental results show that only evolved self-supervised agents can demonstrate some sort of intelligent behaviour, but not evolution or self-learning alone. Indications for future work on evolving intelligence are also presented.

Nam Le

The so-called Baldwin Effect generally says how learning, as a form of ontogenetic adaptation, can influence the process of phylogenetic adaptation, or evolution. This idea has also been taken into computation in which evolution and learning are used as computational metaphors, including evolving neural networks. This paper presents a technique called evolving self-taught neural networks - neural networks that can teach themselves without external supervision or reward. The self-taught neural network is intrinsically motivated. Moreover, the self-taught neural network is the product of the interplay between evolution and learning. We simulate a multi-agent system in which neural networks are used to control autonomous agents. These agents have to forage for resources and compete for their own survival. Experimental results show that the interaction between evolution and the ability to teach oneself in self-taught neural networks outperform evolution and self-teaching alone. More specifically, the emergence of an intelligent foraging strategy is also demonstrated through that interaction. Indications for future work on evolving neural networks are also presented.