Yue Huang

Zhenqi Fu, Wu Wang, Yue Huang et al.

A main challenge faced in the deep learning-based Underwater Image Enhancement (UIE) is that the ground truth high-quality image is unavailable. Most of the existing methods first generate approximate reference maps and then train an enhancement network with certainty. This kind of method fails to handle the ambiguity of the reference map. In this paper, we resolve UIE into distribution estimation and consensus process. We present a novel probabilistic network to learn the enhancement distribution of degraded underwater images. Specifically, we combine conditional variational autoencoder with adaptive instance normalization to construct the enhancement distribution. After that, we adopt a consensus process to predict a deterministic result based on a set of samples from the distribution. By learning the enhancement distribution, our method can cope with the bias introduced in the reference map labeling to some extent. Additionally, the consensus process is useful to capture a robust and stable result. We examined the proposed method on two widely used real-world underwater image enhancement datasets. Experimental results demonstrate that our approach enables sampling possible enhancement predictions. Meanwhile, the consensus estimate yields competitive performance compared with state-of-the-art UIE methods. Code available at https://github.com/zhenqifu/PUIE-Net.

Chenxin Li, Mingbao Lin, Zhiyuan Ding et al.

Knowledge Distillation (KD) transfers the knowledge from a high-capacity teacher network to strengthen a smaller student. Existing methods focus on excavating the knowledge hints and transferring the whole knowledge to the student. However, the knowledge redundancy arises since the knowledge shows different values to the student at different learning stages. In this paper, we propose Knowledge Condensation Distillation (KCD). Specifically, the knowledge value on each sample is dynamically estimated, based on which an Expectation-Maximization (EM) framework is forged to iteratively condense a compact knowledge set from the teacher to guide the student learning. Our approach is easy to build on top of the off-the-shelf KD methods, with no extra training parameters and negligible computation overhead. Thus, it presents one new perspective for KD, in which the student that actively identifies teacher's knowledge in line with its aptitude can learn to learn more effectively and efficiently. Experiments on standard benchmarks manifest that the proposed KCD can well boost the performance of student model with even higher distillation efficiency. Code is available at https://github.com/dzy3/KCD.

Yunlong Zhang, Xin Lin, Yihong Zhuang et al.

Synthesizing a subject-specific pathology-free image from a pathological image is valuable for algorithm development and clinical practice. In recent years, several approaches based on the Generative Adversarial Network (GAN) have achieved promising results in pseudo-healthy synthesis. However, the discriminator (i.e., a classifier) in the GAN cannot accurately identify lesions and further hampers from generating admirable pseudo-healthy images. To address this problem, we present a new type of discriminator, the segmentor, to accurately locate the lesions and improve the visual quality of pseudo-healthy images. Then, we apply the generated images into medical image enhancement and utilize the enhanced results to cope with the low contrast problem existing in medical image segmentation. Furthermore, a reliable metric is proposed by utilizing two attributes of label noise to measure the health of synthetic images. Comprehensive experiments on the T2 modality of BraTS demonstrate that the proposed method substantially outperforms the state-of-the-art methods. The method achieves better performance than the existing methods with only 30\% of the training data. The effectiveness of the proposed method is also demonstrated on the LiTS and the T1 modality of BraTS. The code and the pre-trained model of this study are publicly available at https://github.com/Au3C2/Generator-Versus-Segmentor.

Chaoqi Chen, Jiongcheng Li, Hong-Yu Zhou et al.

Domain Adaptive Object Detection (DAOD) focuses on improving the generalization ability of object detectors via knowledge transfer. Recent advances in DAOD strive to change the emphasis of the adaptation process from global to local in virtue of fine-grained feature alignment methods. However, both the global and local alignment approaches fail to capture the topological relations among different foreground objects as the explicit dependencies and interactions between and within domains are neglected. In this case, only seeking one-vs-one alignment does not necessarily ensure the precise knowledge transfer. Moreover, conventional alignment-based approaches may be vulnerable to catastrophic overfitting regarding those less transferable regions (e.g. backgrounds) due to the accumulation of inaccurate localization results in the target domain. To remedy these issues, we first formulate DAOD as an open-set domain adaptation problem, in which the foregrounds and backgrounds are seen as the ``known classes'' and ``unknown class'' respectively. Accordingly, we propose a new and general framework for DAOD, named Foreground-aware Graph-based Relational Reasoning (FGRR), which incorporates graph structures into the detection pipeline to explicitly model the intra- and inter-domain foreground object relations on both pixel and semantic spaces, thereby endowing the DAOD model with the capability of relational reasoning beyond the popular alignment-based paradigm. The inter-domain visual and semantic correlations are hierarchically modeled via bipartite graph structures, and the intra-domain relations are encoded via graph attention mechanisms. Empirical results demonstrate that the proposed FGRR exceeds the state-of-the-art performance on four DAOD benchmarks.

Chaoqi Chen, Luyao Tang, Feng Liu et al.

Domain generalization (DG) enables generalizing a learning machine from multiple seen source domains to an unseen target one. The general objective of DG methods is to learn semantic representations that are independent of domain labels, which is theoretically sound but empirically challenged due to the complex mixture of common and domain-specific factors. Although disentangling the representations into two disjoint parts has been gaining momentum in DG, the strong presumption over the data limits its efficacy in many real-world scenarios. In this paper, we propose Mix and Reason (\mire), a new DG framework that learns semantic representations via enforcing the structural invariance of semantic topology. \mire\ consists of two key components, namely, Category-aware Data Mixing (CDM) and Adaptive Semantic Topology Refinement (ASTR). CDM mixes two images from different domains in virtue of activation maps generated by two complementary classification losses, making the classifier focus on the representations of semantic objects. ASTR introduces relation graphs to represent semantic topology, which is progressively refined via the interactions between local feature aggregation and global cross-domain relational reasoning. Experiments on multiple DG benchmarks validate the effectiveness and robustness of the proposed \mire.

Zhijie Rao, Jingcai Guo, Luyao Tang et al.

This paper provides a novel framework for single-domain generalized object detection (i.e., Single-DGOD), where we are interested in learning and maintaining the semantic structures of self-augmented compound cross-domain samples to enhance the model's generalization ability. Different from DGOD trained on multiple source domains, Single-DGOD is far more challenging to generalize well to multiple target domains with only one single source domain. Existing methods mostly adopt a similar treatment from DGOD to learn domain-invariant features by decoupling or compressing the semantic space. However, there may have two potential limitations: 1) pseudo attribute-label correlation, due to extremely scarce single-domain data; and 2) the semantic structural information is usually ignored, i.e., we found the affinities of instance-level semantic relations in samples are crucial to model generalization. In this paper, we introduce Semantic Reasoning with Compound Domains (SRCD) for Single-DGOD. Specifically, our SRCD contains two main components, namely, the texture-based self-augmentation (TBSA) module, and the local-global semantic reasoning (LGSR) module. TBSA aims to eliminate the effects of irrelevant attributes associated with labels, such as light, shadow, color, etc., at the image level by a light-yet-efficient self-augmentation. Moreover, LGSR is used to further model the semantic relationships on instance features to uncover and maintain the intrinsic semantic structures. Extensive experiments on multiple benchmarks demonstrate the effectiveness of the proposed SRCD.

Haote Xu, Yunlong Zhang, Liyan Sun et al.

Anomaly Detection (AD) on medical images enables a model to recognize any type of anomaly pattern without lesion-specific supervised learning. Data augmentation based methods construct pseudo-healthy images by "pasting" fake lesions on real healthy ones, and a network is trained to predict healthy images in a supervised manner. The lesion can be found by difference between the unhealthy input and pseudo-healthy output. However, using only manually designed fake lesions fail to approximate to irregular real lesions, hence limiting the model generalization. We assume by exploring the intrinsic data property within images, we can distinguish previously unseen lesions from healthy regions in an unhealthy image. In this study, we propose an Adaptive Fourier Space Compression (AFSC) module to distill healthy feature for AD. The compression of both magnitude and phase in frequency domain addresses the hyper intensity and diverse position of lesions. Experimental results on the BraTS and MS-SEG datasets demonstrate an AFSC baseline is able to produce promising detection results, and an AFSC module can be effectively embedded into existing AD methods.

Yiyang Liu, Chenxin Li, Xiaotong Tu et al.

Knowledge Distillation (KD) transfers the knowledge from a high-capacity teacher model to promote a smaller student model. Existing efforts guide the distillation by matching their prediction logits, feature embedding, etc., while leaving how to efficiently utilize them in junction less explored. In this paper, we propose Hint-dynamic Knowledge Distillation, dubbed HKD, which excavates the knowledge from the teacher' s hints in a dynamic scheme. The guidance effect from the knowledge hints usually varies in different instances and learning stages, which motivates us to customize a specific hint-learning manner for each instance adaptively. Specifically, a meta-weight network is introduced to generate the instance-wise weight coefficients about knowledge hints in the perception of the dynamical learning progress of the student model. We further present a weight ensembling strategy to eliminate the potential bias of coefficient estimation by exploiting the historical statics. Experiments on standard benchmarks of CIFAR-100 and Tiny-ImageNet manifest that the proposed HKD well boost the effect of knowledge distillation tasks.

Changxing Jing, Yan Huang, Yihong Zhuang et al.

Federated Learning (FL) is developed to learn a single global model across the decentralized data, while is susceptible when realizing client-specific personalization in the presence of statistical heterogeneity. However, studies focus on learning a robust global model or personalized classifiers, which yield divergence due to inconsistent objectives. This paper shows that it is possible to achieve flexible personalization after the convergence of the global model by introducing representation learning. In this paper, we first analyze and determine that non-IID data harms representation learning of the global model. Existing FL methods adhere to the scheme of jointly learning representations and classifiers, where the global model is an average of classification-based local models that are consistently subject to heterogeneity from non-IID data. As a solution, we separate representation learning from classification learning in FL and propose RepPer, an independent two-stage personalized FL framework.We first learn the client-side feature representation models that are robust to non-IID data and aggregate them into a global common representation model. After that, we achieve personalization by learning a classifier head for each client, based on the common representation obtained at the former stage. Notably, the proposed two-stage learning scheme of RepPer can be potentially used for lightweight edge computing that involves devices with constrained computation power.Experiments on various datasets (CIFAR-10/100, CINIC-10) and heterogeneous data setup show that RepPer outperforms alternatives in flexibility and personalization on non-IID data.

Zhenyu Kuang, Hongyang Zhang, Mang Ye et al.

Generalizable vehicle re-identification (ReID) seeks to develop models that can adapt to unknown target domains without the need for additional fine-tuning or retraining. Previous works have mainly focused on extracting domain-invariant features by aligning data distributions between source domains. However, interfered by the inherent domain-related redundancy in the source images, solely relying on common features is insufficient for accurately capturing the complementary features with lower occurrence probability and smaller energy. To solve this unique problem, we propose a two-stage Multi-expert Knowledge Confrontation and Collaboration (MiKeCoCo) method, which fully leverages the high-level semantics of Contrastive Language-Image Pretraining (CLIP) to obtain a diversified prompt set and achieve complementary feature representations. Specifically, this paper first designs a Spectrum-based Transformation for Redundancy Elimination and Augmentation Module (STREAM) through simple image preprocessing to obtain two types of image inputs for the training process. Since STREAM eliminates domain-related redundancy in source images, it enables the model to pay closer attention to the detailed prompt set that is crucial for distinguishing fine-grained vehicles. This learned prompt set related to the vehicle identity is then utilized to guide the comprehensive representation learning of complementary features for final knowledge fusion and identity recognition. Inspired by the unity principle, MiKeCoCo integrates the diverse evaluation ways of experts to ensure the accuracy and consistency of ReID. Extensive experimental results demonstrate that our method achieves state-of-the-art performance.

Linyu Fan, Che Wang, Ming Ye et al.

Data-centric artificial intelligence (AI) has remarkably advanced medical imaging, with emerging methods using synthetic data to address data scarcity while introducing synthetic-to-real gaps. Unsupervised domain adaptation (UDA) shows promise in ground truth-scarce tasks, but its application in reconstruction remains underexplored. Although multiple overlapping-echo detachment (MOLED) achieves ultra-fast multi-parametric reconstruction, extending its application to various clinical scenarios, the quality suffers from deficiency in mitigating the domain gap, difficulty in maintaining structural integrity, and inadequacy in ensuring mapping accuracy. To resolve these issues, we proposed frequency-aware perturbation and selection (FPS), comprising Wasserstein distance-modulated frequency-aware perturbation (WDFP) and hierarchical frequency-aware selection network (HFSNet), which integrates frequency-aware adaptive selection (FAS), compact FAS (cFAS) and feature-aware architecture integration (FAI). Specifically, perturbation activates domain-invariant feature learning within uncertainty, while selection refines optimal solutions within perturbation, establishing a robust and closed-loop learning pathway. Extensive experiments on synthetic data, along with diverse real clinical cases from 5 healthy volunteers, 94 ischemic stroke patients, and 46 meningioma patients, demonstrate the superiority and clinical applicability of FPS. Furthermore, FPS is applied to diffusion tensor imaging (DTI), underscoring its versatility and potential for broader medical applications. The code is available at https://github.com/flyannie/FPS.

Guanxing Zhou, Hao Liang, Xinghao Ding et al.

Acoustic source localization has been applied in different fields, such as aeronautics and ocean science, generally using multiple microphones array data to reconstruct the source location. However, the model-based beamforming methods fail to achieve the high-resolution of conventional beamforming maps. Deep neural networks are also appropriate to locate the sound source, but in general, these methods with complex network structures are hard to be recognized by hardware. In this paper, a novel neural network, termed the Acoustic-Net, is proposed to locate and quantify the sound source simply using the original signals. The experiments demonstrate that the proposed method significantly improves the accuracy of sound source prediction and the computing speed, which may generalize well to real data. The code and trained models are available at https://github.com/JoaquinChou/Acoustic-Net.

Zhongnan Cai, Yingying Wang, Yunlong Lin et al.

Recently, deep learning-based pan-sharpening algorithms have achieved notable advancements over traditional methods. However, many deep learning-based approaches incur substantial computational overhead during inference, especially with high-resolution images. This excessive computational demand limits the applicability of these methods in real-world scenarios, particularly in the absence of dedicated computing devices such as GPUs and TPUs. To address these challenges, we propose Pan-LUT, a novel learnable look-up table (LUT) framework for pan-sharpening that strikes a balance between performance and computational efficiency for high-resolution remote sensing images. To finely control the spectral transformation, we devise the PAN-guided look-up table (PGLUT) for channel-wise spectral mapping. To effectively capture fine-grained spatial details and adaptively learn local contexts, we introduce the spatial details look-up table (SDLUT) and adaptive aggregation look-up table (AALUT). Our proposed method contains fewer than 300K parameters and processes a 8K resolution image in under 1 ms using a single NVIDIA GeForce RTX 2080 Ti GPU, demonstrating significantly faster performance compared to other methods. Experiments reveal that Pan-LUT efficiently processes large remote sensing images in a lightweight manner, bridging the gap to real-world applications. Furthermore, our model surpasses SOTA methods in full-resolution scenes under real-world conditions, highlighting its effectiveness and efficiency.

Yuexing Hao, Yue Huang, Haoran Zhang et al.

Cutting-edge research in Artificial Intelligence (AI) requires considerable resources, including Graphics Processing Units (GPUs), data, and human resources. In this paper, we evaluate of the relationship between these resources and the scientific advancement of foundation models (FM). We reviewed 6517 FM papers published between 2022 to 2024, and surveyed 229 first-authors to the impact of computing resources on scientific output. We find that increased computing is correlated with national funding allocations and citations, but our findings don't observe the strong correlations with research environment (academic or industrial), domain, or study methodology. We advise that individuals and institutions focus on creating shared and affordable computing opportunities to lower the entry barrier for under-resourced researchers. These steps can help expand participation in FM research, foster diversity of ideas and contributors, and sustain innovation and progress in AI. The data will be available at: https://mit-calc.csail.mit.edu/

Huangxing Lin, Yihong Zhuang, Delu Zeng et al.

We devise a new regularization, called self-verification, for image denoising. This regularization is formulated using a deep image prior learned by the network, rather than a traditional predefined prior. Specifically, we treat the output of the network as a ``prior'' that we denoise again after ``re-noising''. The comparison between the again denoised image and its prior can be interpreted as a self-verification of the network's denoising ability. We demonstrate that self-verification encourages the network to capture low-level image statistics needed to restore the image. Based on this self-verification regularization, we further show that the network can learn to denoise even if it has not seen any clean images. This learning strategy is self-supervised, and we refer to it as Self-Verification Image Denoising (SVID). SVID can be seen as a mixture of learning-based methods and traditional model-based denoising methods, in which regularization is adaptively formulated using the output of the network. We show the application of SVID to various denoising tasks using only observed corrupted data. It can achieve the denoising performance close to supervised CNNs.

Chenxin Li, Qi Qi, Xinghao Ding et al.

Medical imaging datasets usually exhibit domain shift due to the variations of scanner vendors, imaging protocols, etc. This raises the concern about the generalization capacity of machine learning models. Domain generalization (DG), which aims to learn a model from multiple source domains such that it can be directly generalized to unseen test domains, seems particularly promising to medical imaging community. To address DG, recent model-agnostic meta-learning (MAML) has been introduced, which transfers the knowledge from previous training tasks to facilitate the learning of novel testing tasks. However, in clinical practice, there are usually only a few annotated source domains available, which decreases the capacity of training task generation and thus increases the risk of overfitting to training tasks in the paradigm. In this paper, we propose a novel DG scheme of episodic training with task augmentation on medical imaging classification. Based on meta-learning, we develop the paradigm of episodic training to construct the knowledge transfer from episodic training-task simulation to the real testing task of DG. Motivated by the limited number of source domains in real-world medical deployment, we consider the unique task-level overfitting and we propose task augmentation to enhance the variety during training task generation to alleviate it. With the established learning framework, we further exploit a novel meta-objective to regularize the deep embedding of training domains. To validate the effectiveness of the proposed method, we perform experiments on histopathological images and abdominal CT images.

Chenxin Li, Wenao Ma, Liyan Sun et al.

The analysis of organ vessels is essential for computer-aided diagnosis and surgical planning. But it is not a easy task since the fine-detailed connected regions of organ vessel bring a lot of ambiguity in vessel segmentation and sub-type recognition, especially for the low-contrast capillary regions. Furthermore, recent two-staged approaches would accumulate and even amplify these inaccuracies from the first-stage whole vessel segmentation into the second-stage sub-type vessel pixel-wise classification. Moreover, the scarcity of manual annotation in organ vessels poses another challenge. In this paper, to address the above issues, we propose a hierarchical deep network where an attention mechanism localizes the low-contrast capillary regions guided by the whole vessels, and enhance the spatial activation in those areas for the sub-type vessels. In addition, we propose an uncertainty-aware semi-supervised training framework to alleviate the annotation-hungry limitation of deep models. The proposed method achieves the state-of-the-art performance in the benchmarks of both retinal artery/vein segmentation in fundus images and liver portal/hepatic vessel segmentation in CT images.

Wu Wang, Yue Huang, Xinhao Ding

Hyperspectral image fusion (HIF) is critical to a wide range of applications in remote sensing and many computer vision applications. Most traditional HIF methods assume that the observation model is predefined or known. However, in real applications, the observation model involved are often complicated and unknown, which leads to the serious performance drop of many advanced HIF methods. Also, deep learning methods can achieve outstanding performance, but they generally require a large number of image pairs for model training, which are difficult to obtain in realistic scenarios. Towards these issues, we proposed a self-regression learning method that alternatively reconstructs hyperspectral image (HSI) and estimate the observation model. In particular, we adopt an invertible neural network (INN) for restoring the HSI, and two fully-connected network (FCN) for estimating the observation model. Moreover, \emph{SoftMax} nonlinearity is applied to the FCN for satisfying the non-negative, sparsity and equality constraints. Besides, we proposed a local consistency loss function to constrain the observation model by exploring domain specific knowledge. Finally, we proposed an angular loss function to improve spectral reconstruction accuracy. Extensive experiments on both synthetic and real-world dataset show that our model can outperform the state-of-the-art methods

Chaoqi Chen, Zebiao Zheng, Yue Huang et al.

Recent works on two-stage cross-domain detection have widely explored the local feature patterns to achieve more accurate adaptation results. These methods heavily rely on the region proposal mechanisms and ROI-based instance-level features to design fine-grained feature alignment modules with respect to the foreground objects. However, for one-stage detectors, it is hard or even impossible to obtain explicit instance-level features in the detection pipelines. Motivated by this, we propose an Implicit Instance-Invariant Network (I3Net), which is tailored for adapting one-stage detectors and implicitly learns instance-invariant features via exploiting the natural characteristics of deep features in different layers. Specifically, we facilitate the adaptation from three aspects: (1) Dynamic and Class-Balanced Reweighting (DCBR) strategy, which considers the coexistence of intra-domain and intra-class variations to assign larger weights to those sample-scarce categories and easy-to-adapt samples; (2) Category-aware Object Pattern Matching (COPM) module, which boosts the cross-domain foreground objects matching guided by the categorical information and suppresses the uninformative background features; (3) Regularized Joint Category Alignment (RJCA) module, which jointly enforces the category alignment at different domain-specific layers with a consistency regularization. Experiments reveal that I3Net exceeds the state-of-the-art performance on benchmark datasets.

Chenxin Li, Yunlong Zhang, Zhehan Liang et al.

Retinal artery/vein (A/V) classification is a critical technique for diagnosing diabetes and cardiovascular diseases. Although deep learning based methods achieve impressive results in A/V classification, their performances usually degrade severely when being directly applied to another database, due to the domain shift, e.g., caused by the variations in imaging protocols. In this paper, we propose a novel vessel-mixing based consistency regularization framework, for cross-domain learning in retinal A/V classification. Specially, to alleviate the severe bias to source domain, based on the label smooth prior, the model is regularized to give consistent predictions for unlabeled target-domain inputs that are under perturbation. This consistency regularization implicitly introduces a mechanism where the model and the perturbation is opponent to each other, where the model is pushed to be robust enough to cope with the perturbation. Thus, we investigate a more difficult opponent to further inspire the robustness of model, in the scenario of retinal A/V, called vessel-mixing perturbation. Specially, it effectively disturbs the fundus images especially the vessel structures by mixing two images regionally. We conduct extensive experiments on cross-domain A/V classification using four public datasets, which are collected by diverse institutions and imaging devices. The results demonstrate that our method achieves the state-of-the-art cross-domain performance, which is also close to the upper bound obtained by fully supervised learning on target domain.

Chenxin Li, Yunlong Zhang, Jiongcheng Li et al.

The goal of unsupervised anomaly segmentation (UAS) is to detect the pixel-level anomalies unseen during training. It is a promising field in the medical imaging community, e.g, we can use the model trained with only healthy data to segment the lesions of rare diseases. Existing methods are mainly based on Information Bottleneck, whose underlying principle is modeling the distribution of normal anatomy via learning to compress and recover the healthy data with a low-dimensional manifold, and then detecting lesions as the outlier from this learned distribution. However, this dimensionality reduction inevitably damages the localization information, which is especially essential for pixel-level anomaly detection. In this paper, to alleviate this issue, we introduce the semantic space of healthy anatomy in the process of modeling healthy-data distribution. More precisely, we view the couple of segmentation and synthesis as a special Autoencoder, and propose a novel cycle translation framework with a journey of 'image->semantic->image'. Experimental results on the BraTS and ISLES databases show that the proposed approach achieves significantly superior performance compared to several prior methods and segments the anomalies more accurately.

Zhenqi Fu, Xiaopeng Lin, Wu Wang et al.

We present a novel underwater image enhancement method termed SCNet to improve the image quality meanwhile cope with the degradation diversity caused by the water. SCNet is based on normalization schemes across both spatial and channel dimensions with the key idea of learning water type desensitized features. Specifically, we apply whitening to de-correlate activations across spatial dimensions for each instance in a mini-batch. We also eliminate channel-wise correlation by standardizing and re-injecting the first two moments of the activations across channels. The normalization schemes of spatial and channel dimensions are performed at each scale of the U-Net to obtain multi-scale representations. With such water type irrelevant encodings, the decoder can easily reconstruct the clean signal and be unaffected by the distortion types. Experimental results on two real-world underwater image datasets show that our approach can successfully enhance images with diverse water types, and achieves competitive performance in visual quality improvement.

Zhenqi Fu, Xueyang Fu, Yue Huang et al.

To improve the quality of underwater images, various kinds of underwater image enhancement (UIE) operators have been proposed during the past few years. However, the lack of effective objective evaluation methods limits the further development of UIE techniques. In this paper, we propose a novel rank learning guided no-reference quality assessment method for UIE. Our approach, termed Twice Mixing, is motivated by the observation that a mid-quality image can be generated by mixing a high-quality image with its low-quality version. Typical mixup algorithms linearly interpolate a given pair of input data. However, the human visual system is non-uniformity and non-linear in processing images. Therefore, instead of directly training a deep neural network based on the mixed images and their absolute scores calculated by linear combinations, we propose to train a Siamese Network to learn their quality rankings. Twice Mixing is trained based on an elaborately formulated self-supervision mechanism. Specifically, before each iteration, we randomly generate two mixing ratios which will be employed for both generating virtual images and guiding the network training. In the test phase, a single branch of the network is extracted to predict the quality rankings of different UIE outputs. We conduct extensive experiments on both synthetic and real-world datasets. Experimental results demonstrate that our approach outperforms the previous methods significantly.

Liyan Sun, Chenxin Li, Xinghao Ding et al.

Despite deep convolutional neural networks achieved impressive progress in medical image computing and analysis, its paradigm of supervised learning demands a large number of annotations for training to avoid overfitting and achieving promising results. In clinical practices, massive semantic annotations are difficult to acquire in some conditions where specialized biomedical expert knowledge is required, and it is also a common condition where only few annotated classes are available. In this work, we proposed a novel method for few-shot medical image segmentation, which enables a segmentation model to fast generalize to an unseen class with few training images. We construct our few-shot image segmentor using a deep convolutional network trained episodically. Motivated by the spatial consistency and regularity in medical images, we developed an efficient global correlation module to capture the correlation between a support and query image and incorporate it into the deep network called global correlation network. Moreover, we enhance discriminability of deep embedding to encourage clustering of the feature domains of the same class while keep the feature domains of different organs far apart. Ablation Study proved the effectiveness of the proposed global correlation module and discriminative embedding loss. Extensive experiments on anatomical abdomen images on both CT and MRI modalities are performed to demonstrate the state-of-the-art performance of our proposed model.

Huangxing Lin, Yihong Zhuang, Yue Huang et al.

The effectiveness of existing denoising algorithms typically relies on accurate pre-defined noise statistics or plenty of paired data, which limits their practicality. In this work, we focus on denoising in the more common case where noise statistics and paired data are unavailable. Considering that denoising CNNs require supervision, we develop a new \textbf{adaptive noise imitation (ADANI)} algorithm that can synthesize noisy data from naturally noisy images. To produce realistic noise, a noise generator takes unpaired noisy/clean images as input, where the noisy image is a guide for noise generation. By imposing explicit constraints on the type, level and gradient of noise, the output noise of ADANI will be similar to the guided noise, while keeping the original clean background of the image. Coupling the noisy data output from ADANI with the corresponding ground-truth, a denoising CNN is then trained in a fully-supervised manner. Experiments show that the noisy data produced by ADANI are visually and statistically similar to real ones so that the denoising CNN in our method is competitive to other networks trained with external paired data.

Liyan Sun, Jianxiong Wu, Xinghao Ding et al.

Standard segmentation of medical images based on full-supervised convolutional networks demands accurate dense annotations. Such learning framework is built on laborious manual annotation with restrict demands for expertise, leading to insufficient high-quality labels. To overcome such limitation and exploit massive weakly labeled data, we relaxed the rigid labeling requirement and developed a semi-supervised learning framework based on a teacher-student fashion for organ and lesion segmentation with partial dense-labeled supervision and supplementary loose bounding-box supervision which are easier to acquire. Observing the geometrical relation of an organ and its inner lesions in most cases, we propose a hierarchical organ-to-lesion (O2L) attention module in a teacher segmentor to produce pseudo-labels. Then a student segmentor is trained with combinations of manual-labeled and pseudo-labeled annotations. We further proposed a localization branch realized via an aggregation of high-level features in a deep decoder to predict locations of organ and lesion, which enriches student segmentor with precise localization information. We validated each design in our model on LiTS challenge datasets by ablation study and showed its state-of-the-art performance compared with recent methods. We show our model is robust to the quality of bounding box and achieves comparable performance compared with full-supervised learning methods.

Yunlong Zhang, Changxing Jing, Huangxing Lin et al.

Domain adaptation (DA) aims to transfer knowledge from a label-rich and related domain (source domain) to a label-scare domain (target domain). Pseudo-labeling has recently been widely explored and used in DA. However, this line of research is still confined to the inaccuracy of pseudo-labels. In this paper, we reveal an interesting observation that the target samples belonging to the classes with larger domain shift are easier to be misclassified compared with the other classes. These classes are called hard class, which deteriorates the performance of DA and restricts the applications of DA. We propose a novel framework, called Hard Class Rectification Pseudo-labeling (HCRPL), to alleviate the hard class problem from two aspects. First, as is difficult to identify the target samples as hard class, we propose a simple yet effective scheme, named Adaptive Prediction Calibration (APC), to calibrate the predictions of the target samples according to the difficulty degree for each class. Second, we further consider that the predictions of target samples belonging to the hard class are vulnerable to perturbations. To prevent these samples to be misclassified easily, we introduce Temporal-Ensembling (TE) and Self-Ensembling (SE) to obtain consistent predictions. The proposed method is evaluated in both unsupervised domain adaptation (UDA) and semi-supervised domain adaptation (SSDA). The experimental results on several real-world cross-domain benchmarks, including ImageCLEF, Office-31 and Office-Home, substantiates the superiority of the proposed method.

Chaoqi Chen, Zebiao Zheng, Xinghao Ding et al.

Recent advances in adaptive object detection have achieved compelling results in virtue of adversarial feature adaptation to mitigate the distributional shifts along the detection pipeline. Whilst adversarial adaptation significantly enhances the transferability of feature representations, the feature discriminability of object detectors remains less investigated. Moreover, transferability and discriminability may come at a contradiction in adversarial adaptation given the complex combinations of objects and the differentiated scene layouts between domains. In this paper, we propose a Hierarchical Transferability Calibration Network (HTCN) that hierarchically (local-region/image/instance) calibrates the transferability of feature representations for harmonizing transferability and discriminability. The proposed model consists of three components: (1) Importance Weighted Adversarial Training with input Interpolation (IWAT-I), which strengthens the global discriminability by re-weighting the interpolated image-level features; (2) Context-aware Instance-Level Alignment (CILA) module, which enhances the local discriminability by capturing the underlying complementary effect between the instance-level feature and the global context information for the instance-level feature alignment; (3) local feature masks that calibrate the local transferability to provide semantic guidance for the following discriminative pattern alignment. Experimental results show that HTCN significantly outperforms the state-of-the-art methods on benchmark datasets.

Huangxing Lin, Weihong Zeng, Xinghao Ding et al.

We propose a new framework called Noise2Blur (N2B) for training robust image denoising models without pre-collected paired noisy/clean images. The training of the model requires only some (or even one) noisy images, some random unpaired clean images, and noise-free but blurred labels obtained by predefined filtering of the noisy images. The N2B model consists of two parts: a denoising network and a noise extraction network. First, the noise extraction network learns to output a noise map using the noise information from the denoising network under the guidence of the blurred labels. Then, the noise map is added to a clean image to generate a new "noisy/clean" image pair. Using the new image pair, the denoising network learns to generate clean and high-quality images from noisy observations. These two networks are trained simultaneously and mutually aid each other to learn the mappings of noise to clean/blur. Experiments on several denoising tasks show that the denoising performance of N2B is close to that of other denoising CNNs trained with pre-collected paired data.

Huangxing Lin, Weihong Zeng, Xinghao Ding et al.

The performance of a deep neural network is highly dependent on its training, and finding better local optimal solutions is the goal of many optimization algorithms. However, existing optimization algorithms show a preference for descent paths that converge slowly and do not seek to avoid bad local optima. In this work, we propose Learning Rate Dropout (LRD), a simple gradient descent technique for training related to coordinate descent. LRD empirically aids the optimizer to actively explore in the parameter space by randomly setting some learning rates to zero; at each iteration, only parameters whose learning rate is not 0 are updated. As the learning rate of different parameters is dropped, the optimizer will sample a new loss descent path for the current update. The uncertainty of the descent path helps the model avoid saddle points and bad local minima. Experiments show that LRD is surprisingly effective in accelerating training while preventing overfitting.

Jiexiang Wang, Hongyu Huang, Chaoqi Chen et al.

Automatic and accurate segmentation of the ventricles and myocardium from multi-sequence cardiac MRI (CMR) is crucial for the diagnosis and treatment management for patients suffering from myocardial infarction (MI). However, due to the existence of domain shift among different modalities of datasets, the performance of deep neural networks drops significantly when the training and testing datasets are distinct. In this paper, we propose an unsupervised domain alignment method to explicitly alleviate the domain shifts among different modalities of CMR sequences, \emph{e.g.,} bSSFP, LGE, and T2-weighted. Our segmentation network is attention U-Net with pyramid pooling module, where multi-level feature space and output space adversarial learning are proposed to transfer discriminative domain knowledge across different datasets. Moreover, we further introduce a group-wise feature recalibration module to enforce the fine-grained semantic-level feature alignment that matching features from different networks but with the same class label. We evaluate our method on the multi-sequence cardiac MR Segmentation Challenge 2019 datasets, which contain three different modalities of MRI sequences. Extensive experimental results show that the proposed methods can obtain significant segmentation improvements compared with the baseline models.

Chaoqi Chen, Weiping Xie, Tingyang Xu et al.

Graph alignment, also known as network alignment, is a fundamental task in social network analysis. Many recent works have relied on partially labeled cross-graph node correspondences, i.e., anchor links. However, due to the privacy and security issue, the manual labeling of anchor links for diverse scenarios may be prohibitive. Aligning two graphs without any anchor links is a crucial and challenging task. In this paper, we propose an Unsupervised Adversarial Graph Alignment (UAGA) framework to learn a cross-graph alignment between two embedding spaces of different graphs in a fully unsupervised fashion (\emph{i.e.,} no existing anchor links and no users' personal profile or attribute information is available). The proposed framework learns the embedding spaces of each graph, and then attempts to align the two spaces via adversarial training, followed by a refinement procedure. We further extend our UAGA method to incremental UAGA (iUAGA) that iteratively reveals the unobserved user links based on the pseudo anchor links. This can be used to further improve both the embedding quality and the alignment accuracy. Moreover, the proposed methods will benefit some real-world applications, \emph{e.g.,} link prediction in social networks. Comprehensive experiments on real-world data demonstrate the effectiveness of our proposed approaches UAGA and iUAGA for unsupervised graph alignment.

Huangxing Lin, Yanlong Li, Xinghao Ding et al.

We present a supervised technique for learning to remove rain from images without using synthetic rain software. The method is based on a two-stage data distillation approach: 1) A rainy image is first paired with a coarsely derained version using on a simple filtering technique ("rain-to-clean"). 2) Then a clean image is randomly matched with the rainy soft-labeled pair. Through a shared deep neural network, the rain that is removed from the first image is then added to the clean image to generate a second pair ("clean-to-rain"). The neural network simultaneously learns to map both images such that high resolution structure in the clean images can inform the deraining of the rainy images. Demonstrations show that this approach can address those visual characteristics of rain not easily synthesized by software in the usual way.

Huangxing Lin, Xueyang Fu, Changxing Jing et al.

Existing methods for single images raindrop removal either have poor robustness or suffer from parameter burdens. In this paper, we propose a new Adjacent Aggregation Network (A^2Net) with lightweight architectures to remove raindrops from single images. Instead of directly cascading convolutional layers, we design an adjacent aggregation architecture to better fuse features for rich representations generation, which can lead to high quality images reconstruction. To further simplify the learning process, we utilize a problem-specific knowledge to force the network focus on the luminance channel in the YUV color space instead of all RGB channels. By combining adjacent aggregating operation with color space transformation, the proposed A^2Net can achieve state-of-the-art performances on raindrop removal with significant parameters reduction.

Xueyang Fu, Qi Qi, Yue Huang et al.

We propose a simple yet effective deep tree-structured fusion model based on feature aggregation for the deraining problem. We argue that by effectively aggregating features, a relatively simple network can still handle tough image deraining problems well. First, to capture the spatial structure of rain we use dilated convolutions as our basic network block. We then design a tree-structured fusion architecture which is deployed within each block (spatial information) and across all blocks (content information). Our method is based on the assumption that adjacent features contain redundant information. This redundancy obstructs generation of new representations and can be reduced by hierarchically fusing adjacent features. Thus, the proposed model is more compact and can effectively use spatial and content information. Experiments on synthetic and real-world datasets show that our network achieves better deraining results with fewer parameters.

Chaoqi Chen, Weiping Xie, Wenbing Huang et al.

Unsupervised domain adaptation (UDA) transfers knowledge from a label-rich source domain to a fully-unlabeled target domain. To tackle this task, recent approaches resort to discriminative domain transfer in virtue of pseudo-labels to enforce the class-level distribution alignment across the source and target domains. These methods, however, are vulnerable to the error accumulation and thus incapable of preserving cross-domain category consistency, as the pseudo-labeling accuracy is not guaranteed explicitly. In this paper, we propose the Progressive Feature Alignment Network (PFAN) to align the discriminative features across domains progressively and effectively, via exploiting the intra-class variation in the target domain. To be specific, we first develop an Easy-to-Hard Transfer Strategy (EHTS) and an Adaptive Prototype Alignment (APA) step to train our model iteratively and alternatively. Moreover, upon observing that a good domain adaptation usually requires a non-saturated source classifier, we consider a simple yet efficient way to retard the convergence speed of the source classification loss by further involving a temperature variate into the soft-max function. The extensive experimental results reveal that the proposed PFAN exceeds the state-of-the-art performance on three UDA datasets.

Liyan Sun, Jiexiang Wang, Yue Huang et al.

The identification of lesion within medical image data is necessary for diagnosis, treatment and prognosis. Segmentation and classification approaches are mainly based on supervised learning with well-paired image-level or voxel-level labels. However, labeling the lesion in medical images is laborious requiring highly specialized knowledge. We propose a medical image synthesis model named abnormal-to-normal translation generative adversarial network (ANT-GAN) to generate a normal-looking medical image based on its abnormal-looking counterpart without the need for paired training data. Unlike typical GANs, whose aim is to generate realistic samples with variations, our more restrictive model aims at producing a normal-looking image corresponding to one containing lesions, and thus requires a special design. Being able to provide a "normal" counterpart to a medical image can provide useful side information for medical imaging tasks like lesion segmentation or classification validated by our experiments. In the other aspect, the ANT-GAN model is also capable of producing highly realistic lesion-containing image corresponding to the healthy one, which shows the potential in data augmentation verified in our experiments.

Xueyang Fu, Borong Liang, Yue Huang et al.

Existing deep convolutional neural networks have found major success in image deraining, but at the expense of an enormous number of parameters. This limits their potential application, for example in mobile devices. In this paper, we propose a lightweight pyramid of networks (LPNet) for single image deraining. Instead of designing a complex network structures, we use domain-specific knowledge to simplify the learning process. Specifically, we find that by introducing the mature Gaussian-Laplacian image pyramid decomposition technology to the neural network, the learning problem at each pyramid level is greatly simplified and can be handled by a relatively shallow network with few parameters. We adopt recursive and residual network structures to build the proposed LPNet, which has less than 8K parameters while still achieving state-of-the-art performance on rain removal. We also discuss the potential value of LPNet for other low- and high-level vision tasks.

Xinghao Ding, Zhirui Lin, Fujin He et al.

The estimation of crowd count in images has a wide range of applications such as video surveillance, traffic monitoring, public safety and urban planning. Recently, the convolutional neural network (CNN) based approaches have been shown to be more effective in crowd counting than traditional methods that use handcrafted features. However, the existing CNN-based methods still suffer from large number of parameters and large storage space, which require high storage and computing resources and thus limit the real-world application. Consequently, we propose a deeply-recursive network (DR-ResNet) based on ResNet blocks for crowd counting. The recursive structure makes the network deeper while keeping the number of parameters unchanged, which enhances network capability to capture statistical regularities in the context of the crowd. Besides, we generate a new dataset from the video-monitoring data of Beijing bus station. Experimental results have demonstrated that proposed method outperforms most state-of-the-art methods with far less number of parameters.

Liyan Sun, Zhiwen Fan, Yue Huang et al.

The need for fast acquisition and automatic analysis of MRI data is growing in the age of big data. Although compressed sensing magnetic resonance imaging (CS-MRI) has been studied to accelerate MRI by reducing k-space measurements, in current CS-MRI techniques MRI applications such as segmentation are overlooked when doing image reconstruction. In this paper, we test the utility of CS-MRI methods in automatic segmentation models and propose a unified deep neural network architecture called SegNetMRI which we apply to the combined CS-MRI reconstruction and segmentation problem. SegNetMRI is built upon a MRI reconstruction network with multiple cascaded blocks each containing an encoder-decoder unit and a data fidelity unit, and MRI segmentation networks having the same encoder-decoder structure. The two subnetworks are pre-trained and fine-tuned with shared reconstruction encoders. The outputs are merged into the final segmentation. Our experiments show that SegNetMRI can improve both the reconstruction and segmentation performance when using compressive measurements.

Zhiwen Fan, Liyan Sun, Xinghao Ding et al.

Compressed sensing MRI is a classic inverse problem in the field of computational imaging, accelerating the MR imaging by measuring less k-space data. The deep neural network models provide the stronger representation ability and faster reconstruction compared with "shallow" optimization-based methods. However, in the existing deep-based CS-MRI models, the high-level semantic supervision information from massive segmentation-labels in MRI dataset is overlooked. In this paper, we proposed a segmentation-aware deep fusion network called SADFN for compressed sensing MRI. The multilayer feature aggregation (MLFA) method is introduced here to fuse all the features from different layers in the segmentation network. Then, the aggregated feature maps containing semantic information are provided to each layer in the reconstruction network with a feature fusion strategy. This guarantees the reconstruction network is aware of the different regions in the image it reconstructs, simplifying the function mapping. We prove the utility of the cross-layer and cross-task information fusion strategy by comparative study. Extensive experiments on brain segmentation benchmark MRBrainS validated that the proposed SADFN model achieves state-of-the-art accuracy in compressed sensing MRI. This paper provides a novel approach to guide the low-level visual task using the information from mid- or high-level task.

Liyan Sun, Zhiwen Fan, Xinghao Ding et al.

Compressed sensing (CS) theory assures us that we can accurately reconstruct magnetic resonance images using fewer k-space measurements than the Nyquist sampling rate requires. In traditional CS-MRI inversion methods, the fact that the energy within the Fourier measurement domain is distributed non-uniformly is often neglected during reconstruction. As a result, more densely sampled low-frequency information tends to dominate penalization schemes for reconstructing MRI at the expense of high-frequency details. In this paper, we propose a new framework for CS-MRI inversion in which we decompose the observed k-space data into "subspaces" via sets of filters in a lossless way, and reconstruct the images in these various spaces individually using off-the-shelf algorithms. We then fuse the results to obtain the final reconstruction. In this way we are able to focus reconstruction on frequency information within the entire k-space more equally, preserving both high and low frequency details. We demonstrate that the proposed framework is competitive with state-of-the-art methods in CS-MRI in terms of quantitative performance, and often improves an algorithm's results qualitatively compared with it's direct application to k-space.

Liyan Sun, Zhiwen Fan, Yue Huang et al.

Compressed sensing for magnetic resonance imaging (CS-MRI) exploits image sparsity properties to reconstruct MRI from very few Fourier k-space measurements. The goal is to minimize any structural errors in the reconstruction that could have a negative impact on its diagnostic quality. To this end, we propose a deep error correction network (DECN) for CS-MRI. The DECN model consists of three parts, which we refer to as modules: a guide, or template, module, an error correction module, and a data fidelity module. Existing CS-MRI algorithms can serve as the template module for guiding the reconstruction. Using this template as a guide, the error correction module learns a convolutional neural network (CNN) to map the k-space data in a way that adjusts for the reconstruction error of the template image. Our experimental results show the proposed DECN CS-MRI reconstruction framework can considerably improve upon existing inversion algorithms by supplementing with an error-correcting CNN.

Tong Zhao, Lin Li, Xinghao Ding et al.

In this letter, an effective image saliency detection method is proposed by constructing some novel spaces to model the background and redefine the distance of the salient patches away from the background. Concretely, given the backgroundness prior, eigendecomposition is utilized to create four spaces of background-based distribution (SBD) to model the background, in which a more appropriate metric (Mahalanobis distance) is quoted to delicately measure the saliency of every image patch away from the background. After that, a coarse saliency map is obtained by integrating the four adjusted Mahalanobis distance maps, each of which is formed by the distances between all the patches and background in the corresponding SBD. To be more discriminative, the coarse saliency map is further enhanced into the posterior probability map within Bayesian perspective. Finally, the final saliency map is generated by properly refining the posterior probability map with geodesic distance. Experimental results on two usual datasets show that the proposed method is effective compared with the state-of-the-art algorithms.

Yue Huang, John Paisley, Qin Lin et al.

We develop a Bayesian nonparametric model for reconstructing magnetic resonance images (MRI) from highly undersampled k-space data. We perform dictionary learning as part of the image reconstruction process. To this end, we use the beta process as a nonparametric dictionary learning prior for representing an image patch as a sparse combination of dictionary elements. The size of the dictionary and the patch-specific sparsity pattern are inferred from the data, in addition to other dictionary learning variables. Dictionary learning is performed directly on the compressed image, and so is tailored to the MRI being considered. In addition, we investigate a total variation penalty term in combination with the dictionary learning model, and show how the denoising property of dictionary learning removes dependence on regularization parameters in the noisy setting. We derive a stochastic optimization algorithm based on Markov Chain Monte Carlo (MCMC) for the Bayesian model, and use the alternating direction method of multipliers (ADMM) for efficiently performing total variation minimization. We present empirical results on several MRI, which show that the proposed regularization framework can improve reconstruction accuracy over other methods.