Zhaoxi Zhang

Shuxian Wang, Akshay Paruchuri, Zhaoxi Zhang et al. · stanford

Monocular depth estimation in colonoscopy video aims to overcome the unusual lighting properties of the colonoscopic environment. One of the major challenges in this area is the domain gap between annotated but unrealistic synthetic data and unannotated but realistic clinical data. Previous attempts to bridge this domain gap directly target the depth estimation task itself. We propose a general pipeline of structure-preserving synthetic-to-real (sim2real) image translation (producing a modified version of the input image) to retain depth geometry through the translation process. This allows us to generate large quantities of realistic-looking synthetic images for supervised depth estimation with improved generalization to the clinical domain. We also propose a dataset of hand-picked sequences from clinical colonoscopies to improve the image translation process. We demonstrate the simultaneous realism of the translated images and preservation of depth maps via the performance of downstream depth estimation on various datasets.

Hsiu-Yuan Huang, Yutong Yang, Zhaoxi Zhang et al.

As large language models (LLMs) continue to evolve, understanding and quantifying the uncertainty in their predictions is critical for enhancing application credibility. However, the existing literature relevant to LLM uncertainty estimation often relies on heuristic approaches, lacking systematic classification of the methods. In this survey, we clarify the definitions of uncertainty and confidence, highlighting their distinctions and implications for model predictions. On this basis, we integrate theoretical perspectives, including Bayesian inference, information theory, and ensemble strategies, to categorize various classes of uncertainty estimation methods derived from heuristic approaches. Additionally, we address challenges that arise when applying these methods to LLMs. We also explore techniques for incorporating uncertainty into diverse applications, including out-of-distribution detection, data annotation, and question clarification. Our review provides insights into uncertainty estimation from both definitional and theoretical angles, contributing to a comprehensive understanding of this critical aspect in LLMs. We aim to inspire the development of more reliable and effective uncertainty estimation approaches for LLMs in real-world scenarios.

Guankun Wang, Long Bai, Wan Jun Nah et al.

Recent advancements in Surgical Visual Question Answering (Surgical-VQA) and related region grounding have shown great promise for robotic and medical applications, addressing the critical need for automated methods in personalized surgical mentorship. However, existing models primarily provide simple structured answers and struggle with complex scenarios due to their limited capability in recognizing long-range dependencies and aligning multimodal information. In this paper, we introduce Surgical-LVLM, a novel personalized large vision-language model tailored for complex surgical scenarios. Leveraging the pre-trained large vision-language model and specialized Visual Perception LoRA (VP-LoRA) blocks, our model excels in understanding complex visual-language tasks within surgical contexts. In addressing the visual grounding task, we propose the Token-Interaction (TIT) module, which strengthens the interaction between the grounding module and the language responses of the Large Visual Language Model (LVLM) after projecting them into the latent space. We demonstrate the effectiveness of Surgical-LVLM on several benchmarks, including EndoVis-17-VQLA, EndoVis-18-VQLA, and a newly introduced EndoVis Conversations dataset, which sets new performance standards. Our work contributes to advancing the field of automated surgical mentorship by providing a context-aware solution.

Yanguang Zhao, Long Bai, Zhaoxi Zhang et al.

Glioma, a common and deadly brain tumor, requires early diagnosis for improved prognosis. However, low-quality Magnetic Resonance Imaging (MRI) technology in Sub-Saharan Africa (SSA) hinders accurate diagnosis. This paper presents our work in the BraTS Challenge on SSA Adult Glioma. We adopt the model from the BraTS-GLI 2021 winning solution and utilize it with three training strategies: (1) initially training on the BraTS-GLI 2021 dataset with fine-tuning on the BraTS-Africa dataset, (2) training solely on the BraTS-Africa dataset, and (3) training solely on the BraTS-Africa dataset with 2x super-resolution enhancement. Results show that initial training on the BraTS-GLI 2021 dataset followed by fine-tuning on the BraTS-Africa dataset has yielded the best results. This suggests the importance of high-quality datasets in providing prior knowledge during training. Our top-performing model achieves Dice scores of 0.882, 0.840, and 0.926, and Hausdorff Distance (95%) scores of 15.324, 37.518, and 13.971 for enhancing tumor, tumor core, and whole tumor, respectively, in the validation phase. In the final phase of the competition, our approach successfully secured second place overall, reflecting the strength and effectiveness of our model and training strategies. Our approach provides insights into improving glioma diagnosis in SSA, showing the potential of deep learning in resource-limited settings and the importance of transfer learning from high-quality datasets.

Zhaoxi Zhang, Yueliang Ying

Computed tomography (CT) provides highly detailed three-dimensional (3D) medical images but is costly, time-consuming, and often inaccessible in intraoperative settings (Organization et al. 2011). Recent advancements have explored reconstructing 3D chest volumes from sparse 2D X-rays, such as single-view or orthogonal double-view images. However, current models tend to process 2D images in a planar manner, prioritizing visual realism over structural accuracy. In this work, we introduce DuoLift Generative Adversarial Networks (DuoLift-GAN), a novel architecture with dual branches that independently elevate 2D images and their features into 3D representations. These 3D outputs are merged into a unified 3D feature map and decoded into a complete 3D chest volume, enabling richer 3D information capture. We also present a masked loss function that directs reconstruction towards critical anatomical regions, improving structural accuracy and visual quality. This paper demonstrates that DuoLift-GAN significantly enhances reconstruction accuracy while achieving superior visual realism compared to existing methods.