Min Wu

Fakai Wang, Kang Zheng, Le Lu et al.

Accurate vertebra localization and identification are required in many clinical applications of spine disorder diagnosis and surgery planning. However, significant challenges are posed in this task by highly varying pathologies (such as vertebral compression fracture, scoliosis, and vertebral fixation) and imaging conditions (such as limited field of view and metal streak artifacts). This paper proposes a robust and accurate method that effectively exploits the anatomical knowledge of the spine to facilitate vertebra localization and identification. A key point localization model is trained to produce activation maps of vertebra centers. They are then re-sampled along the spine centerline to produce spine-rectified activation maps, which are further aggregated into 1-D activation signals. Following this, an anatomically-constrained optimization module is introduced to jointly search for the optimal vertebra centers under a soft constraint that regulates the distance between vertebrae and a hard constraint on the consecutive vertebra indices. When being evaluated on a major public benchmark of 302 highly pathological CT images, the proposed method reports the state of the art identification (id.) rate of 97.4%, and outperforms the best competing method of 94.7% id. rate by reducing the relative id. error rate by half.

Mingliang Chen, Min Wu

Effective machine learning models can automatically learn useful information from a large quantity of data and provide decisions in a high accuracy. These models may, however, lead to unfair predictions in certain sense among the population groups of interest, where the grouping is based on such sensitive attributes as race and gender. Various fairness definitions, such as demographic parity and equalized odds, were proposed in prior art to ensure that decisions guided by the machine learning models are equitable. Unfortunately, the "fair" model trained with these fairness definitions is threshold sensitive, i.e., the condition of fairness may no longer hold true when tuning the decision threshold. This paper introduces the notion of threshold invariant fairness, which enforces equitable performances across different groups independent of the decision threshold. To achieve this goal, this paper proposes to equalize the risk distributions among the groups via two approximation methods. Experimental results demonstrate that the proposed methodology is effective to alleviate the threshold sensitivity in machine learning models designed to achieve fairness.

Abbas Kazemipour, Ji Liu, Patrick Kanold et al.

In this paper, we consider linear state-space models with compressible innovations and convergent transition matrices in order to model spatiotemporally sparse transient events. We perform parameter and state estimation using a dynamic compressed sensing framework and develop an efficient solution consisting of two nested Expectation-Maximization (EM) algorithms. Under suitable sparsity assumptions on the innovations, we prove recovery guarantees and derive confidence bounds for the state estimates. We provide simulation studies as well as application to spike deconvolution from calcium imaging data which verify our theoretical results and show significant improvement over existing algorithms.