Mengjia Chen

Mengjia Chen, Changxin Qiu, Zhiping Mao et al.

The numerical simulation of interaction between free flow and porous media, governed by coupled Stokes/Navier--Stokes--Darcy flows, is critical for understanding fluid filtration and physiological transport, yet it is hindered by the high computational cost of resolving interface heterogeneities and the instability of long-term predictions. While deep learning offers surrogate modeling potential, existing frameworks often suffer from exponential error accumulation and poor convergence in multi-physics regimes. To address these limitations, we propose ViT-K, a novel few-shot learning model designed to learn the spatiotemporal evolution of coupled flows from sparse datasets. The ViT-K framework effectively reconstructs the global flow physics on a low-dimensional manifold by combining Vision Transformers (ViT) to capture heterogeneous interfacial features with the Koopman operator to linearize temporal dynamics. By lifting nonlinear dynamics into a globally linear observable space, the ViT-K model provides stability by design, ensuring that prediction errors grow linearly rather than exponentially over time. This theoretical property enables reliable long-term extrapolation even in small-sample regimes. Numerical experiments on benchmark coupled systems demonstrate that ViT-K not only captures complex interface physics with high fidelity but also exhibits exceptional robustness against measurement noise by acting as an implicit spectral filter. The proposed method significantly outperforms traditional solvers in inference speed while maintaining physical consistency, offering a robust paradigm for real-time multiphysics forecasting.

Zhengyao Ding, Ziyu Li, Yujian Hu et al.

Cardiovascular diseases (CVDs) are the leading cause of global mortality, necessitating accessible and accurate diagnostic tools. While cardiac magnetic resonance imaging (CMR) provides gold-standard insights into cardiac structure and function, its clinical utility is limited by high cost and complexity. In contrast, electrocardiography (ECG) is inexpensive and widely available but lacks the granularity of CMR. We propose CardioNets, a deep learning framework that translates 12-lead ECG signals into CMR-level functional parameters and synthetic images, enabling scalable cardiac assessment. CardioNets integrates cross-modal contrastive learning and generative pretraining, aligning ECG with CMR-derived cardiac phenotypes and synthesizing high-resolution CMR images via a masked autoregressive model. Trained on 159,819 samples from five cohorts, including the UK Biobank (n=42,483) and MIMIC-IV-ECG (n=164,550), and externally validated on independent clinical datasets (n=3,767), CardioNets achieved strong performance across disease screening and phenotype estimation tasks. In the UK Biobank, it improved cardiac phenotype regression R2 by 24.8% and cardiomyopathy AUC by up to 39.3% over baseline models. In MIMIC, it increased AUC for pulmonary hypertension detection by 5.6%. Generated CMR images showed 36.6% higher SSIM and 8.7% higher PSNR than prior approaches. In a reader study, ECG-only CardioNets achieved 13.9% higher accuracy than human physicians using both ECG and real CMR. These results suggest that CardioNets offers a promising, low-cost alternative to CMR for large-scale CVD screening, particularly in resource-limited settings. Future efforts will focus on clinical deployment and regulatory validation of ECG-based synthetic imaging.