Yi Feng

Yi Feng, Mingyang Song, Jiaqi Wang et al.

Children with Autism Spectrum Disorder (ASD) often misunderstand social situations and struggle to participate in daily routines. Social Stories are traditionally crafted by psychology experts under strict constraints to address these challenges but are costly and limited in diversity. As Large Language Models (LLMs) advance, there's an opportunity to develop more automated, affordable, and accessible methods to generate Social Stories in real-time with broad coverage. However, adapting LLMs to meet the unique and strict constraints of Social Stories is a challenging issue. To this end, we propose SS-GEN, a Social Story GENeration framework with LLMs. Firstly, we develop a constraint-driven sophisticated strategy named StarSow to hierarchically prompt LLMs to generate Social Stories at scale, followed by rigorous human filtering to build a high-quality dataset. Additionally, we introduce quality assessment criteria to evaluate the effectiveness of these generated stories. Considering that powerful closed-source large models require very complex instructions and expensive API fees, we finally fine-tune smaller language models with our curated high-quality dataset, achieving comparable results at lower costs and with simpler instruction and deployment. This work marks a significant step in leveraging AI to personalize Social Stories cost-effectively for autistic children at scale, which we hope can encourage future research on special groups.

Ronald B. Liu, Zhe Liu, Max G. A. Wolf et al.

Advancements in high-throughput biomedical applications require real-time, large field-of-view (FOV) imaging. While current 2D lens-free imaging (LFI) systems improve FOV, they are often hindered by time-consuming multi-position measurements, extensive data pre-processing, and strict optical parameterization, limiting their application to static, thin samples. To overcome these limitations, we introduce GenLFI, combining a generative unsupervised physics-informed neural network (PINN) with a large FOV LFI setup for straightforward holographic image reconstruction, without multi-measurement. GenLFI enables real-time 2D imaging for 3D samples, such as droplet-based microfluidics and 3D cell models, in dynamic complex optical fields. Unlike previous methods, our approach decouples the reconstruction algorithm from optical setup parameters, enabling a large FOV limited only by hardware. We demonstrate a real-time FOV exceeding 550 mm$^2$, over 20 times larger than current real-time LFI systems. This framework unlocks the potential of LFI systems, providing a robust tool for advancing automated high-throughput biomedical applications.