Yawen Wu

Yawen Wu, Dewen Zeng, Xiaowei Xu et al.

Many works have shown that deep learning-based medical image classification models can exhibit bias toward certain demographic attributes like race, gender, and age. Existing bias mitigation methods primarily focus on learning debiased models, which may not necessarily guarantee all sensitive information can be removed and usually comes with considerable accuracy degradation on both privileged and unprivileged groups. To tackle this issue, we propose a method, FairPrune, that achieves fairness by pruning. Conventionally, pruning is used to reduce the model size for efficient inference. However, we show that pruning can also be a powerful tool to achieve fairness. Our observation is that during pruning, each parameter in the model has different importance for different groups' accuracy. By pruning the parameters based on this importance difference, we can reduce the accuracy difference between the privileged group and the unprivileged group to improve fairness without a large accuracy drop. To this end, we use the second derivative of the parameters of a pre-trained model to quantify the importance of each parameter with respect to the model accuracy for each group. Experiments on two skin lesion diagnosis datasets over multiple sensitive attributes demonstrate that our method can greatly improve fairness while keeping the average accuracy of both groups as high as possible.

Yawen Wu, Dewen Zeng, Zhepeng Wang et al.

Supervised deep learning needs a large amount of labeled data to achieve high performance. However, in medical imaging analysis, each site may only have a limited amount of data and labels, which makes learning ineffective. Federated learning (FL) can learn a shared model from decentralized data. But traditional FL requires fully-labeled data for training, which is very expensive to obtain. Self-supervised contrastive learning (CL) can learn from unlabeled data for pre-training, followed by fine-tuning with limited annotations. However, when adopting CL in FL, the limited data diversity on each site makes federated contrastive learning (FCL) ineffective. In this work, we propose two federated self-supervised learning frameworks for volumetric medical image segmentation with limited annotations. The first one features high accuracy and fits high-performance servers with high-speed connections. The second one features lower communication costs, suitable for mobile devices. In the first framework, features are exchanged during FCL to provide diverse contrastive data to each site for effective local CL while keeping raw data private. Global structural matching aligns local and remote features for a unified feature space among different sites. In the second framework, to reduce the communication cost for feature exchanging, we propose an optimized method FCLOpt that does not rely on negative samples. To reduce the communications of model download, we propose the predictive target network update (PTNU) that predicts the parameters of the target network. Based on PTNU, we propose the distance prediction (DP) to remove most of the uploads of the target network. Experiments on a cardiac MRI dataset show the proposed two frameworks substantially improve the segmentation and generalization performance compared with state-of-the-art techniques.

Yawen Wu, Dewen Zeng, Zhepeng Wang et al.

In dermatological disease diagnosis, the private data collected by mobile dermatology assistants exist on distributed mobile devices of patients. Federated learning (FL) can use decentralized data to train models while keeping data local. Existing FL methods assume all the data have labels. However, medical data often comes without full labels due to high labeling costs. Self-supervised learning (SSL) methods, contrastive learning (CL) and masked autoencoders (MAE), can leverage the unlabeled data to pre-train models, followed by fine-tuning with limited labels. However, combining SSL and FL has unique challenges. For example, CL requires diverse data but each device only has limited data. For MAE, while Vision Transformer (ViT) based MAE has higher accuracy over CNNs in centralized learning, MAE's performance in FL with unlabeled data has not been investigated. Besides, the ViT synchronization between the server and clients is different from traditional CNNs. Therefore, special synchronization methods need to be designed. In this work, we propose two federated self-supervised learning frameworks for dermatological disease diagnosis with limited labels. The first one features lower computation costs, suitable for mobile devices. The second one features high accuracy and fits high-performance servers. Based on CL, we proposed federated contrastive learning with feature sharing (FedCLF). Features are shared for diverse contrastive information without sharing raw data for privacy. Based on MAE, we proposed FedMAE. Knowledge split separates the global and local knowledge learned from each client. Only global knowledge is aggregated for higher generalization performance. Experiments on dermatological disease datasets show superior accuracy of the proposed frameworks over state-of-the-arts.

Jiahe Shi, Yawen Wu, Dewen Zeng et al.

The ubiquity of edge devices has led to a growing amount of unlabeled data produced at the edge. Deep learning models deployed on edge devices are required to learn from these unlabeled data to continuously improve accuracy. Self-supervised representation learning has achieved promising performances using centralized unlabeled data. However, the increasing awareness of privacy protection limits centralizing the distributed unlabeled image data on edge devices. While federated learning has been widely adopted to enable distributed machine learning with privacy preservation, without a data selection method to efficiently select streaming data, the traditional federated learning framework fails to handle these huge amounts of decentralized unlabeled data with limited storage resources on edge. To address these challenges, we propose a Self-supervised On-device Federated learning framework with coreset selection, which we call SOFed, to automatically select a coreset that consists of the most representative samples into the replay buffer on each device. It preserves data privacy as each client does not share raw data while learning good visual representations. Experiments demonstrate the effectiveness and significance of the proposed method in visual representation learning.

Gelei Xu, Yawen Wu, Jingtong Hu et al.

Dermatological diseases pose a major threat to the global health, affecting almost one-third of the world's population. Various studies have demonstrated that early diagnosis and intervention are often critical to prognosis and outcome. To this end, the past decade has witnessed the rapid evolvement of deep learning based smartphone apps, which allow users to conveniently and timely identify issues that have emerged around their skins. In order to collect sufficient data needed by deep learning and at the same time protect patient privacy, federated learning is often used, where individual clients aggregate a global model while keeping datasets local. However, existing federated learning frameworks are mostly designed to optimize the overall performance, while common dermatological datasets are heavily imbalanced. When applying federated learning to such datasets, significant disparities in diagnosis accuracy may occur. To address such a fairness issue, this paper proposes a fairness-aware federated learning framework for dermatological disease diagnosis. The framework is divided into two stages: In the first in-FL stage, clients with different skin types are trained in a federated learning process to construct a global model for all skin types. An automatic weight aggregator is used in this process to assign higher weights to the client with higher loss, and the intensity of the aggregator is determined by the level of difference between losses. In the latter post-FL stage, each client fine-tune its personalized model based on the global model in the in-FL stage. To achieve better fairness, models from different epochs are selected for each client to keep the accuracy difference of different skin types within 0.05. Experiments indicate that our proposed framework effectively improves both fairness and accuracy compared with the state-of-the-art.

Zhepeng Wang, Runxue Bao, Yawen Wu et al.

Pretrained large language models (LLMs) have revolutionized natural language processing (NLP) tasks such as summarization, question answering, and translation. However, LLMs pose significant security risks due to their tendency to memorize training data, leading to potential privacy breaches and copyright infringement. Accurate measurement of this memorization is essential to evaluate and mitigate these potential risks. However, previous attempts to characterize memorization are constrained by either using prefixes only or by prepending a constant soft prompt to the prefixes, which cannot react to changes in input. To address this challenge, we propose a novel method for estimating LLM memorization using dynamic, prefix-dependent soft prompts. Our approach involves training a transformer-based generator to produce soft prompts that adapt to changes in input, thereby enabling more accurate extraction of memorized data. Our method not only addresses the limitations of previous methods but also demonstrates superior performance in diverse experimental settings compared to state-of-the-art techniques. In particular, our method can achieve the maximum relative improvement of 112.75% and 32.26% over the vanilla baseline in terms of discoverable memorization rate for the text generation task and code generation task respectively.

Yue Tang, Yawen Wu, Peipei Zhou et al.

Detecting actions in videos have been widely applied in on-device applications. Practical on-device videos are always untrimmed with both action and background. It is desirable for a model to both recognize the class of action and localize the temporal position where the action happens. Such a task is called temporal action location (TAL), which is always trained on the cloud where multiple untrimmed videos are collected and labeled. It is desirable for a TAL model to continuously and locally learn from new data, which can directly improve the action detection precision while protecting customers' privacy. However, it is non-trivial to train a TAL model, since tremendous video samples with temporal annotations are required. However, annotating videos frame by frame is exorbitantly time-consuming and expensive. Although weakly-supervised TAL (W-TAL) has been proposed to learn from untrimmed videos with only video-level labels, such an approach is also not suitable for on-device learning scenarios. In practical on-device learning applications, data are collected in streaming. Dividing such a long video stream into multiple video segments requires lots of human effort, which hinders the exploration of applying the TAL tasks to realistic on-device learning applications. To enable W-TAL models to learn from a long, untrimmed streaming video, we propose an efficient video learning approach that can directly adapt to new environments. We first propose a self-adaptive video dividing approach with a contrast score-based segment merging approach to convert the video stream into multiple segments. Then, we explore different sampling strategies on the TAL tasks to request as few labels as possible. To the best of our knowledge, we are the first attempt to directly learn from the on-device, long video stream.

Pan Wang, Qiang Zhou, Yawen Wu et al.

Multimodal Sentiment Analysis (MSA) leverages heterogeneous modalities, such as language, vision, and audio, to enhance the understanding of human sentiment. While existing models often focus on extracting shared information across modalities or directly fusing heterogeneous modalities, such approaches can introduce redundancy and conflicts due to equal treatment of all modalities and the mutual transfer of information between modality pairs. To address these issues, we propose a Disentangled-Language-Focused (DLF) multimodal representation learning framework, which incorporates a feature disentanglement module to separate modality-shared and modality-specific information. To further reduce redundancy and enhance language-targeted features, four geometric measures are introduced to refine the disentanglement process. A Language-Focused Attractor (LFA) is further developed to strengthen language representation by leveraging complementary modality-specific information through a language-guided cross-attention mechanism. The framework also employs hierarchical predictions to improve overall accuracy. Extensive experiments on two popular MSA datasets, CMU-MOSI and CMU-MOSEI, demonstrate the significant performance gains achieved by the proposed DLF framework. Comprehensive ablation studies further validate the effectiveness of the feature disentanglement module, language-focused attractor, and hierarchical predictions. Our code is available at https://github.com/pwang322/DLF.

Zixuan Pan, Jun Xia, Zheyu Yan et al.

Reconstruction-based methods, particularly those leveraging autoencoders, have been widely adopted for anomaly detection task in brain MRI. Unlike most existing works try to improve the task accuracy through architectural or algorithmic innovations, we tackle this task from image quality assessment (IQA) perspective, an under-explored direction in the field. Due to the limitations of conventional metrics such as l1 in capturing the nuanced differences in reconstructed images for medical anomaly detection, we propose fusion quality, a novel metric that wisely integrates the structure-level sensitivity of Structural Similarity Index Measure (SSIM) with the pixel-level precision of l1. The metric offers a more comprehensive assessment of reconstruction quality, considering intensity (subtractive property of l1 and divisive property of SSIM), contrast, and structural similarity. Furthermore, the proposed metric makes subtle regional variations more impactful in the final assessment. Thus, considering the inherent divisive properties of SSIM, we design an average intensity ratio (AIR)-based data transformation that amplifies the divisive discrepancies between normal and abnormal regions, thereby enhancing anomaly detection. By fusing the aforementioned two components, we devise the IQA approach. Experimental results on two distinct brain MRI datasets show that our IQA approach significantly enhances medical anomaly detection performance when integrated with state-of-the-art baselines.

Zhepeng Wang, Runxue Bao, Yawen Wu et al.

Graph neural networks (GNNs) are powerful machine learning models designed to handle irregularly structured data. However, their generic design often proves inadequate for analyzing brain connectomes in Alzheimer's Disease (AD), highlighting the need to incorporate domain knowledge for optimal performance. Infusing AD-related knowledge into GNNs is a complicated task. Existing methods typically rely on collaboration between computer scientists and domain experts, which can be both time-intensive and resource-demanding. To address these limitations, this paper presents a novel self-guided, knowledge-infused multimodal GNN that autonomously incorporates domain knowledge into the model development process. Our approach conceptualizes domain knowledge as natural language and introduces a specialized multimodal GNN capable of leveraging this uncurated knowledge to guide the learning process of the GNN, such that it can improve the model performance and strengthen the interpretability of the predictions. To evaluate our framework, we curated a comprehensive dataset of recent peer-reviewed papers on AD and integrated it with multiple real-world AD datasets. Experimental results demonstrate the ability of our method to extract relevant domain knowledge, provide graph-based explanations for AD diagnosis, and improve the overall performance of the GNN. This approach provides a more scalable and efficient alternative to inject domain knowledge for AD compared with the manual design from the domain expert, advancing both prediction accuracy and interpretability in AD diagnosis.

George Ma, Anurag Koul, Qi Chen et al. · amazon-science

Large Language Models (LLMs) excel at code-related tasks but often struggle in realistic software repositories, where project-specific APIs and cross-file dependencies are crucial. Retrieval-augmented methods mitigate this by injecting repository context at inference time. The low inference-time latency budget affects either retrieval quality or the added latency adversely impacts user experience. We address this limitation with SpecAgent, an agent that improves both latency and code-generation quality by proactively exploring repository files during indexing and constructing speculative context that anticipates future edits in each file. This indexing-time asynchrony allows thorough context computation, masking latency, and the speculative nature of the context improves code-generation quality. Additionally, we identify the problem of future context leakage in existing benchmarks, which can inflate reported performance. To address this, we construct a synthetic, leakage-free benchmark that enables a more realistic evaluation of our agent against baselines. Experiments show that SpecAgent consistently achieves absolute gains of 9-11% (48-58% relative) compared to the best-performing baselines, while significantly reducing inference latency.

Dewen Zeng, Xinrong Hu, Yu-Jen Chen et al.

Weakly supervised semantic segmentation (WSSS) methods using class labels often rely on class activation maps (CAMs) to localize objects. However, traditional CAM-based methods struggle with partial activations and imprecise object boundaries due to optimization discrepancies between classification and segmentation. Recently, the conditional diffusion model (CDM) has been used as an alternative for generating segmentation masks in WSSS, leveraging its strong image generation capabilities tailored to specific class distributions. By modifying or perturbing the condition during diffusion sampling, the related objects can be highlighted in the generated images. Yet, the saliency maps generated by CDMs are prone to noise from background alterations during reverse diffusion. To alleviate the problem, we introduce Contrastive Learning with Diffusion Features (CLDF), a novel method that uses contrastive learning to train a pixel decoder to map the diffusion features from a frozen CDM to a low-dimensional embedding space for segmentation. Specifically, we integrate gradient maps generated from CDM external classifier with CAMs to identify foreground and background pixels with fewer false positives/negatives for contrastive learning, enabling robust pixel embedding learning. Experimental results on four segmentation tasks from two public medical datasets demonstrate that our method significantly outperforms existing baselines.

Ching-Hao Chiu, Yu-Jen Chen, Yawen Wu et al.

In medical image diagnosis, fairness has become increasingly crucial. Without bias mitigation, deploying unfair AI would harm the interests of the underprivileged population and potentially tear society apart. Recent research addresses prediction biases in deep learning models concerning demographic groups (e.g., gender, age, and race) by utilizing demographic (sensitive attribute) information during training. However, many sensitive attributes naturally exist in dermatological disease images. If the trained model only targets fairness for a specific attribute, it remains unfair for other attributes. Moreover, training a model that can accommodate multiple sensitive attributes is impractical due to privacy concerns. To overcome this, we propose a method enabling fair predictions for sensitive attributes during the testing phase without using such information during training. Inspired by prior work highlighting the impact of feature entanglement on fairness, we enhance the model features by capturing the features related to the sensitive and target attributes and regularizing the feature entanglement between corresponding classes. This ensures that the model can only classify based on the features related to the target attribute without relying on features associated with sensitive attributes, thereby improving fairness and accuracy. Additionally, we use disease masks from the Segment Anything Model (SAM) to enhance the quality of the learned feature. Experimental results demonstrate that the proposed method can improve fairness in classification compared to state-of-the-art methods in two dermatological disease datasets.

Dewen Zeng, Yawen Wu, Xinrong Hu et al.

This paper presents a new way to identify additional positive pairs for BYOL, a state-of-the-art (SOTA) self-supervised learning framework, to improve its representation learning ability. Unlike conventional BYOL which relies on only one positive pair generated by two augmented views of the same image, we argue that information from different images with the same label can bring more diversity and variations to the target features, thus benefiting representation learning. To identify such pairs without any label, we investigate TracIn, an instance-based and computationally efficient influence function, for BYOL training. Specifically, TracIn is a gradient-based method that reveals the impact of a training sample on a test sample in supervised learning. We extend it to the self-supervised learning setting and propose an efficient batch-wise per-sample gradient computation method to estimate the pairwise TracIn to represent the similarity of samples in the mini-batch during training. For each image, we select the most similar sample from other images as the additional positive and pull their features together with BYOL loss. Experimental results on two public medical datasets (i.e., ISIC 2019 and ChestX-ray) demonstrate that the proposed method can improve the classification performance compared to other competitive baselines in both semi-supervised and transfer learning settings.

Yi Sheng, Junhuan Yang, Yawen Wu et al.

Along with the progress of AI democratization, neural networks are being deployed more frequently in edge devices for a wide range of applications. Fairness concerns gradually emerge in many applications, such as face recognition and mobile medical. One fundamental question arises: what will be the fairest neural architecture for edge devices? By examining the existing neural networks, we observe that larger networks typically are fairer. But, edge devices call for smaller neural architectures to meet hardware specifications. To address this challenge, this work proposes a novel Fairness- and Hardware-aware Neural architecture search framework, namely FaHaNa. Coupled with a model freezing approach, FaHaNa can efficiently search for neural networks with balanced fairness and accuracy, while guaranteed to meet hardware specifications. Results show that FaHaNa can identify a series of neural networks with higher fairness and accuracy on a dermatology dataset. Target edge devices, FaHaNa finds a neural architecture with slightly higher accuracy, 5.28x smaller size, 15.14% higher fairness score, compared with MobileNetV2; meanwhile, on Raspberry PI and Odroid XU-4, it achieves 5.75x and 5.79x speedup.

Yawen Wu, Zhepeng Wang, Dewen Zeng et al.

Contrastive learning (CL), a self-supervised learning approach, can effectively learn visual representations from unlabeled data. Given the CL training data, generative models can be trained to generate synthetic data to supplement the real data. Using both synthetic and real data for CL training has the potential to improve the quality of learned representations. However, synthetic data usually has lower quality than real data, and using synthetic data may not improve CL compared with using real data. To tackle this problem, we propose a data generation framework with two methods to improve CL training by joint sample generation and contrastive learning. The first approach generates hard samples for the main model. The generator is jointly learned with the main model to dynamically customize hard samples based on the training state of the main model. Besides, a pair of data generators are proposed to generate similar but distinct samples as positive pairs. In joint learning, the hardness of a positive pair is progressively increased by decreasing their similarity. Experimental results on multiple datasets show superior accuracy and data efficiency of the proposed data generation methods applied to CL. For example, about 4.0%, 3.5%, and 2.6% accuracy improvements for linear classification are observed on ImageNet-100, CIFAR-100, and CIFAR-10, respectively. Besides, up to 2x data efficiency for linear classification and up to 5x data efficiency for transfer learning are achieved.

Yawen Wu, Dewen Zeng, Zhepeng Wang et al.

Deep learning models have been deployed in an increasing number of edge and mobile devices to provide healthcare. These models rely on training with a tremendous amount of labeled data to achieve high accuracy. However, for medical applications such as dermatological disease diagnosis, the private data collected by mobile dermatology assistants exist on distributed mobile devices of patients, and each device only has a limited amount of data. Directly learning from limited data greatly deteriorates the performance of learned models. Federated learning (FL) can train models by using data distributed on devices while keeping the data local for privacy. Existing works on FL assume all the data have ground-truth labels. However, medical data often comes without any accompanying labels since labeling requires expertise and results in prohibitively high labor costs. The recently developed self-supervised learning approach, contrastive learning (CL), can leverage the unlabeled data to pre-train a model, after which the model is fine-tuned on limited labeled data for dermatological disease diagnosis. However, simply combining CL with FL as federated contrastive learning (FCL) will result in ineffective learning since CL requires diverse data for learning but each device only has limited data. In this work, we propose an on-device FCL framework for dermatological disease diagnosis with limited labels. Features are shared in the FCL pre-training process to provide diverse and accurate contrastive information. After that, the pre-trained model is fine-tuned with local labeled data independently on each device or collaboratively with supervised federated learning on all devices. Experiments on dermatological disease datasets show that the proposed framework effectively improves the recall and precision of dermatological disease diagnosis compared with state-of-the-art methods.

Yawen Wu, Zhepeng Wang, Dewen Zeng et al.

Collaborative learning enables distributed clients to learn a shared model for prediction while keeping the training data local on each client. However, existing collaborative learning methods require fully-labeled data for training, which is inconvenient or sometimes infeasible to obtain due to the high labeling cost and the requirement of expertise. The lack of labels makes collaborative learning impractical in many realistic settings. Self-supervised learning can address this challenge by learning from unlabeled data. Contrastive learning (CL), a self-supervised learning approach, can effectively learn visual representations from unlabeled image data. However, the distributed data collected on clients are usually not independent and identically distributed (non-IID) among clients, and each client may only have few classes of data, which degrades the performance of CL and learned representations. To tackle this problem, we propose a collaborative contrastive learning framework consisting of two approaches: feature fusion and neighborhood matching, by which a unified feature space among clients is learned for better data representations. Feature fusion provides remote features as accurate contrastive information to each client for better local learning. Neighborhood matching further aligns each client's local features to the remote features such that well-clustered features among clients can be learned. Extensive experiments show the effectiveness of the proposed framework. It outperforms other methods by 11% on IID data and matches the performance of centralized learning.