IVOct 20, 2022
Physics-informed Deep Diffusion MRI Reconstruction with Synthetic Data: Break Training Data Bottleneck in Artificial IntelligenceChen Qian, Haoyu Zhang, Yuncheng Gao et al.
Diffusion magnetic resonance imaging (MRI) is the only imaging modality for non-invasive movement detection of in vivo water molecules, with significant clinical and research applications. Diffusion weighted imaging (DWI) MRI acquired by multi-shot techniques can achieve higher resolution, better signal-to-noise ratio, and lower geometric distortion than single-shot, but suffers from inter-shot motion-induced artifacts. These artifacts cannot be removed prospectively, leading to the absence of artifact-free training labels. Thus, the potential of deep learning in multi-shot DWI reconstruction remains largely untapped. To break the training data bottleneck, here, we propose a Physics-Informed Deep DWI reconstruction method (PIDD) to synthesize high-quality paired training data by leveraging the physical diffusion model (magnitude synthesis) and inter-shot motion-induced phase model (motion phase synthesis). The network is trained only once with 100,000 synthetic samples, achieving encouraging results on multiple realistic in vivo data reconstructions. Advantages over conventional methods include: (a) Better motion artifact suppression and reconstruction stability; (b) Outstanding generalization to multi-scenario reconstructions, including multi-resolution, multi-b-value, multi-under-sampling, multi-vendor, and multi-center; (c) Excellent clinical adaptability to patients with verifications by seven experienced doctors (p<0.001). In conclusion, PIDD presents a novel deep learning framework by exploiting the power of MRI physics, providing a cost-effective and explainable way to break the data bottleneck in deep learning medical imaging.
CVJul 2, 2024
SUPER: Seated Upper Body Pose Estimation using mmWave RadarsBo Zhang, Zimeng Zhou, Boyu Jiang et al.
In industrial countries, adults spend a considerable amount of time sedentary each day at work, driving and during activities of daily living. Characterizing the seated upper body human poses using mmWave radars is an important, yet under-studied topic with many applications in human-machine interaction, transportation and road safety. In this work, we devise SUPER, a framework for seated upper body human pose estimation that utilizes dual-mmWave radars in close proximity. A novel masking algorithm is proposed to coherently fuse data from the radars to generate intensity and Doppler point clouds with complementary information for high-motion but small radar cross section areas (e.g., upper extremities) and low-motion but large RCS areas (e.g. torso). A lightweight neural network extracts both global and local features of upper body and output pose parameters for the Skinned Multi-Person Linear (SMPL) model. Extensive leave-one-subject-out experiments on various motion sequences from multiple subjects show that SUPER outperforms a state-of-the-art baseline method by 30 -- 184%. We also demonstrate its utility in a simple downstream task for hand-object interaction.
21.2MLMay 14
RoSHAP: A Distributional Framework and Robust Metric for Stable Feature AttributionLanxin Xiang, Liang Shi, Youhui Ye et al.
Feature attribution analysis is critical for interpreting machine learning models and supporting reliable data-driven decisions. However, feature attribution measures often exhibit stochastic variation: different train--test splits, random seeds, or model-fitting procedures can produce substantially different attribution values and feature rankings. This paper proposes a framework for incorporating stochastic nature of feature attribution and a robust attribution metric, RoSHAP, for stable feature ranking based on the SHAP metric. The proposed framework models the distribution of feature attribution scores and estimates it through bootstrap resampling and kernel density estimation. We show that, under mild regularity conditions, the aggregated feature attribution score is asymptotically Gaussian, which greatly reduces the computational cost of distribution estimation. The RoSHAP summarizes the distribution of SHAP into a robust feature-ranking criterion that simultaneously rewards features that are active, strong, and stable. Through simulations and real-data experiments, the proposed framework and RoSHAP outperform standard single-run attribution measures in identifying signal features. In addition, models built using RoSHAP-selected features achieve predictive performance comparable to full-feature models while using substantially fewer predictors. The proposed RoSHAP approach improves the stability and interpretability of machine learning models, enabling reliable and consistent insights for analysis.
ROJun 10, 2025Code
Perception Characteristics Distance: Measuring Stability and Robustness of Perception System in Dynamic Conditions under a Certain Decision RuleBoyu Jiang, Liang Shi, Zhengzhi Lin et al.
The performance of perception systems in autonomous driving systems (ADS) is strongly influenced by object distance, scene dynamics, and environmental conditions such as weather. AI-based perception outputs are inherently stochastic, with variability driven by these external factors, while traditional evaluation metrics remain static and event-independent, failing to capture fluctuations in confidence over time. In this work, we introduce the Perception Characteristics Distance (PCD) -- a novel evaluation metric that quantifies the farthest distance at which an object can be reliably detected, incorporating uncertainty in model outputs. To support this, we present the SensorRainFall dataset, collected on the Virginia Smart Road using a sensor-equipped vehicle (cameras, radar, LiDAR) under controlled daylight-clear and daylight-rain scenarios, with precise ground-truth distances to the target objects. Statistical analysis reveals the presence of change points in the variance of detection confidence score with distance. By averaging the PCD values across a range of detection quality thresholds and probabilistic thresholds, we compute the mean PCD (mPCD), which captures the overall perception characteristics of a system with respect to detection distance. Applying state-of-the-art perception models shows that mPCD captures meaningful reliability differences under varying weather conditions -- differences that static metrics overlook. PCD provides a principled, distribution-aware measure of perception performance, supporting safer and more robust ADS operation, while the SensorRainFall dataset offers a valuable benchmark for evaluation. The SensorRainFall dataset is publicly available at https://www.kaggle.com/datasets/datadrivenwheels/sensorrainfall, and the evaluation code is open-sourced at https://github.com/datadrivenwheels/PCD_Python.
CVOct 17, 2025
Robust High-Resolution Multi-Organ Diffusion MRI Using Synthetic-Data-Tuned Prompt LearningChen Qian, Haoyu Zhang, Junnan Ma et al.
Clinical adoption of multi-shot diffusion-weighted magnetic resonance imaging (multi-shot DWI) for body-wide tumor diagnostics is limited by severe motion-induced phase artifacts from respiration, peristalsis, and so on, compounded by multi-organ, multi-slice, multi-direction and multi-b-value complexities. Here, we introduce a reconstruction framework, LoSP-Prompt, that overcomes these challenges through physics-informed modeling and synthetic-data-driven prompt learning. We model inter-shot phase variations as a high-order Locally Smooth Phase (LoSP), integrated into a low-rank Hankel matrix reconstruction. Crucially, the algorithm's rank parameter is automatically set via prompt learning trained exclusively on synthetic abdominal DWI data emulating physiological motion. Validated across 10,000+ clinical images (43 subjects, 4 scanner models, 5 centers), LoSP-Prompt: (1) Achieved twice the spatial resolution of clinical single-shot DWI, enhancing liver lesion conspicuity; (2) Generalized to seven diverse anatomical regions (liver, kidney, sacroiliac, pelvis, knee, spinal cord, brain) with a single model; (3) Outperformed state-of-the-art methods in image quality, artifact suppression, and noise reduction (11 radiologists' evaluations on a 5-point scale, $p<0.05$), achieving 4-5 points (excellent) on kidney DWI, 4 points (good to excellent) on liver, sacroiliac and spinal cord DWI, and 3-4 points (good) on knee and tumor brain. The approach eliminates navigator signals and realistic data supervision, providing an interpretable, robust solution for high-resolution multi-organ multi-shot DWI. Its scanner-agnostic performance signifies transformative potential for precision oncology.