Sanyam Jain

Soren Pedersen, Sanyam Jain, Mikkel Chavez et al.

This paper presents the development of a generative adversarial network (GAN) for synthesizing dental panoramic radiographs. Although exploratory in nature, the study aims to address the scarcity of data in dental research and education. We trained a deep convolutional GAN (DCGAN) using a Wasserstein loss with gradient penalty (WGANGP) on a dataset of 2322 radiographs of varying quality. The focus was on the dentoalveolar regions, other anatomical structures were cropped out. Extensive preprocessing and data cleaning were performed to standardize the inputs while preserving anatomical variability. We explored four candidate models by varying critic iterations, feature depth, and the use of denoising prior to training. A clinical expert evaluated the generated radiographs based on anatomical visibility and realism, using a 5-point scale (1 very poor 5 excellent). Most images showed moderate anatomical depiction, although some were degraded by artifacts. A trade-off was observed the model trained on non-denoised data yielded finer details especially in structures like the mandibular canal and trabecular bone, while a model trained on denoised data offered superior overall image clarity and sharpness. These findings provide a foundation for future work on GAN-based methods in dental imaging.

Sanyam Jain, Khuram Naveed, Illia Oleksiienko et al.

This work introduces InJecteD, a framework for interpreting Denoising Diffusion Probabilistic Models (DDPMs) by analyzing sample trajectories during the denoising process of 2D point cloud generation. We apply this framework to three datasets from the Datasaurus Dozen bullseye, dino, and circle using a simplified DDPM architecture with customizable input and time embeddings. Our approach quantifies trajectory properties, including displacement, velocity, clustering, and drift field dynamics, using statistical metrics such as Wasserstein distance and cosine similarity. By enhancing model transparency, InJecteD supports human AI collaboration by enabling practitioners to debug and refine generative models. Experiments reveal distinct denoising phases: initial noise exploration, rapid shape formation, and final refinement, with dataset-specific behaviors example, bullseyes concentric convergence vs. dinos complex contour formation. We evaluate four model configurations, varying embeddings and noise schedules, demonstrating that Fourier based embeddings improve trajectory stability and reconstruction quality

Sanyam Jain, Bruna Neves de Freitas, Andreas Basse-OConnor et al.

There has been increasing interest in the generation of high-quality, realistic synthetic medical images in recent years. Such synthetic datasets can mitigate the scarcity of public datasets for artificial intelligence research, and can also be used for educational purposes. In this paper, we propose a combination of diffusion-based generation (PanoDiff) and Super-Resolution (SR) for generating synthetic dental panoramic radiographs (PRs). The former generates a low-resolution (LR) seed of a PR (256 X 128) which is then processed by the SR model to yield a high-resolution (HR) PR of size 1024 X 512. For SR, we propose a state-of-the-art transformer that learns local-global relationships, resulting in sharper edges and textures. Experimental results demonstrate a Frechet inception distance score of 40.69 between 7243 real and synthetic images (in HR). Inception scores were 2.55, 2.30, 2.90 and 2.98 for real HR, synthetic HR, real LR and synthetic LR images, respectively. Among a diverse group of six clinical experts, all evaluating a mixture of 100 synthetic and 100 real PRs in a time-limited observation, the average accuracy in distinguishing real from synthetic images was 68.5% (with 50% corresponding to random guessing).