Qianyu Chen

Jinyi Hu, Yuan Yao, Chongyi Wang et al. · tencent-ai, tsinghua

Recently there has been a significant surge in multimodal learning in terms of both image-to-text and text-to-image generation. However, the success is typically limited to English, leaving other languages largely behind. Building a competitive counterpart in other languages is highly challenging due to the low-resource nature of non-English multimodal data (i.e., lack of large-scale, high-quality image-text data). In this work, we propose MPM, an effective training paradigm for training large multimodal models in non-English languages. MPM demonstrates that Multilingual language models can Pivot zero-shot Multimodal learning across languages. Specifically, based on a strong multilingual large language model, multimodal models pretrained on English-only image-text data can well generalize to other languages in a (quasi)-zero-shot manner, even surpassing models trained on image-text data in native languages. Taking Chinese as a practice of MPM, we build large multimodal models VisCPM in image-to-text and text-to-image generation, which achieve state-of-the-art (open-source) performance in Chinese. To facilitate future research, we open-source codes and model weights at https://github.com/OpenBMB/VisCPM.git.

Ao Zhang, Yuan Yao, Qianyu Chen et al.

Scene graph generation (SGG) is designed to extract (subject, predicate, object) triplets in images. Recent works have made a steady progress on SGG, and provide useful tools for high-level vision and language understanding. However, due to the data distribution problems including long-tail distribution and semantic ambiguity, the predictions of current SGG models tend to collapse to several frequent but uninformative predicates (e.g., on, at), which limits practical application of these models in downstream tasks. To deal with the problems above, we propose a novel Internal and External Data Transfer (IETrans) method, which can be applied in a plug-and-play fashion and expanded to large SGG with 1,807 predicate classes. Our IETrans tries to relieve the data distribution problem by automatically creating an enhanced dataset that provides more sufficient and coherent annotations for all predicates. By training on the enhanced dataset, a Neural Motif model doubles the macro performance while maintaining competitive micro performance. The code and data are publicly available at https://github.com/waxnkw/IETrans-SGG.pytorch.

Yuan Yao, Qianyu Chen, Ao Zhang et al.

Vision-language pre-training (VLP) has shown impressive performance on a wide range of cross-modal tasks, where VLP models without reliance on object detectors are becoming the mainstream due to their superior computation efficiency and competitive performance. However, the removal of object detectors also deprives the capability of VLP models in explicit object modeling, which is essential to various position-sensitive vision-language (VL) tasks, such as referring expression comprehension and visual commonsense reasoning. To address the challenge, we introduce PEVL that enhances the pre-training and prompt tuning of VLP models with explicit object position modeling. Specifically, PEVL reformulates discretized object positions and language in a unified language modeling framework, which facilitates explicit VL alignment during pre-training, and also enables flexible prompt tuning for various downstream tasks. We show that PEVL enables state-of-the-art performance of detector-free VLP models on position-sensitive tasks such as referring expression comprehension and phrase grounding, and also improves the performance on position-insensitive tasks with grounded inputs. We make the data and code for this paper publicly available at https://github.com/thunlp/PEVL.

Yuan Yao, Tianyu Yu, Ao Zhang et al. · tsinghua

The recent surge of Multimodal Large Language Models (MLLMs) has fundamentally reshaped the landscape of AI research and industry, shedding light on a promising path toward the next AI milestone. However, significant challenges remain preventing MLLMs from being practical in real-world applications. The most notable challenge comes from the huge cost of running an MLLM with a massive number of parameters and extensive computation. As a result, most MLLMs need to be deployed on high-performing cloud servers, which greatly limits their application scopes such as mobile, offline, energy-sensitive, and privacy-protective scenarios. In this work, we present MiniCPM-V, a series of efficient MLLMs deployable on end-side devices. By integrating the latest MLLM techniques in architecture, pretraining and alignment, the latest MiniCPM-Llama3-V 2.5 has several notable features: (1) Strong performance, outperforming GPT-4V-1106, Gemini Pro and Claude 3 on OpenCompass, a comprehensive evaluation over 11 popular benchmarks, (2) strong OCR capability and 1.8M pixel high-resolution image perception at any aspect ratio, (3) trustworthy behavior with low hallucination rates, (4) multilingual support for 30+ languages, and (5) efficient deployment on mobile phones. More importantly, MiniCPM-V can be viewed as a representative example of a promising trend: The model sizes for achieving usable (e.g., GPT-4V) level performance are rapidly decreasing, along with the fast growth of end-side computation capacity. This jointly shows that GPT-4V level MLLMs deployed on end devices are becoming increasingly possible, unlocking a wider spectrum of real-world AI applications in the near future.

Qiyan Zhao, Xiaofeng Zhang, Shuochen Chang et al.

Recent diffusion-based Multimodal Large Language Models (dMLLMs) suffer from high inference latency and therefore rely on caching techniques to accelerate decoding. However, the application of cache mechanisms often introduces undesirable repetitive text generation, a phenomenon we term the \textbf{Repeat Curse}. To better investigate underlying mechanism behind this issue, we analyze repetition generation through the lens of information flow. Our work reveals three key findings: (1) context tokens aggregate semantic information as anchors and guide the final predictions; (2) as information propagates across layers, the entropy of context tokens converges in deeper layers, reflecting the model's growing prediction certainty; (3) Repetition is typically linked to disruptions in the information flow of context tokens and to the inability of their entropy to converge in deeper layers. Based on these insights, we present \textbf{CoTA}, a plug-and-play method for mitigating repetition. CoTA enhances the attention of context tokens to preserve intrinsic information flow patterns, while introducing a penalty term to the confidence score during decoding to avoid outputs driven by uncertain context tokens. With extensive experiments, CoTA demonstrates significant effectiveness in alleviating repetition and achieves consistent performance improvements on general tasks. Code is available at https://github.com/ErikZ719/CoTA

Qianyu Chen, Shujian Yu

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing diagnostic models are trained either on a single site or under full multi-site access, making them unsuitable for real-world scenarios where clinical data arrive sequentially from different institutions. This results in limited generalization and severe catastrophic forgetting. This paper presents the first continual learning framework specifically designed for fMRI-based diagnosis across heterogeneous clinical sites. Our framework introduces a structure-aware variational autoencoder that synthesizes realistic FC matrices for both patient and control groups. Built on this generative backbone, we develop a multi-level knowledge distillation strategy that aligns predictions and graph representations between new-site data and replayed samples. To further enhance efficiency, we incorporate a hierarchical contextual bandit scheme for adaptive replay sampling. Experiments on multi-site datasets for major depressive disorder (MDD), schizophrenia (SZ), and autism spectrum disorder (ASD) show that the proposed generative model enhances data augmentation quality, and the overall continual learning framework substantially outperforms existing methods in mitigating catastrophic forgetting. Our code is available at https://github.com/4me808/FORGE.

Hang Lu, Guochang Li, Qianyu Chen et al.

Automating radio frequency (RF) amplifier design remains challenging because existing methods suffer from the curse of dimensionality, weak use of domain knowledge, and poor transferability, leading to low data efficiency. Meanwhile, although large language models (LLMs) have shown promise in many scientific domains, applying them directly to RF sizing is nontrivial due to the numerical nature of circuit optimization and the reliance on domain-specific design flows. To address this, this paper proposes RFAmpDesigner, a multi-agent framework that automates RF amplifier sizing. It introduces a resource-allocation middleware that reframes high-dimensional parameter tuning as a low-dimensional resource distribution problem, making it easier to inject sizing knowledge into general-purpose LLMs. The framework also follows standard design practice, enabling LLMs to distinguish between high- and low-cost actions and search in parallel. To realize a self-evolving optimization process, the framework employs retrieval-augmented generation (RAG) to reuse past knowledge and experience from memory base. As a proof of concept, we apply RFAmpDesigner to low noise amplifiers of varying complexity. The experimental results show that it can automatically synthesize designs with fractional bandwidths ranging from 10\% to 80\% and center frequencies from 10 GHz to 50 GHz. To the best of our knowledge, this work develops the first LLM-driven approach for RF amplifier sizing that operates on design concepts instead of treating netlists as text, offering a novel solution to mitigate data scarcity in RF design.

Kerem Delikoyun, Qianyu Chen, Win Sen Kuan et al.

Emergency departments worldwide face rising patient volumes, workforce shortages, and variability in triage decisions that threaten the delivery of timely and accurate care. Current triage methods rely primarily on vital signs, routine laboratory values, and clinicians' judgment, which, while effective, often miss emerging biological signals that could improve risk prediction for infection typing or antibiotic administration in acute conditions. To address this challenge, we introduce TriAgent, a large language model (LLM)-based multi-agent framework that couples automated biomarker discovery with deep research for literature-grounded validation and novelty assessment. TriAgent employs a supervisor research agent to generate research topics and delegate targeted queries to specialized sub-agents for evidence retrieval from various data sources. Findings are synthesized to classify biomarkers as either grounded in existing knowledge or flagged as novel candidates, offering transparent justification and highlighting unexplored pathways in acute care risk stratification. Unlike prior frameworks limited to existing routine clinical biomarkers, TriAgent aims to deliver an end-to-end framework from data analysis to literature grounding to improve transparency, explainability and expand the frontier of potentially actionable clinical biomarkers. Given a user's clinical query and quantitative triage data, TriAgent achieved a topic adherence F1 score of 55.7 +/- 5.0%, surpassing the CoT-ReAct agent by over 10%, and a faithfulness score of 0.42 +/- 0.39, exceeding all baselines by more than 50%. Across experiments, TriAgent consistently outperformed state-of-the-art LLM-based agentic frameworks in biomarker justification and literature-grounded novelty assessment. We share our repo: https://github.com/CellFace/TriAgent.

Bojia Zi, Shihao Zhao, Xianbiao Qi et al.

Recent advancements in video generation have been remarkable, yet many existing methods struggle with issues of consistency and poor text-video alignment. Moreover, the field lacks effective techniques for text-guided video inpainting, a stark contrast to the well-explored domain of text-guided image inpainting. To this end, this paper proposes a novel text-guided video inpainting model that achieves better consistency, controllability and compatibility. Specifically, we introduce a simple but efficient motion capture module to preserve motion consistency, and design an instance-aware region selection instead of a random region selection to obtain better textual controllability, and utilize a novel strategy to inject some personalized models into our CoCoCo model and thus obtain better model compatibility. Extensive experiments show that our model can generate high-quality video clips. Meanwhile, our model shows better motion consistency, textual controllability and model compatibility. More details are shown in [cococozibojia.github.io](cococozibojia.github.io).

Mengzhu Xu, Hanzhi Liu, Ningkang Peng et al.

Continual learning for video--language understanding is increasingly important as models face non-stationary data, domains, and query styles, yet prevailing solutions blur what should stay stable versus what should adapt, rely on static routing/capacity, or require replaying past videos. We aim to explicitly specify where stability lives and where plasticity should be focused under realistic memory and privacy constraints. We introduce Affordance-First Decomposition (AFD): videos are mapped to slowly varying affordance tokens that form a shared, time-aligned substrate, while a lightweight, query-routed, conflict-aware scheduler concentrates adaptation and grows capacity only when needed. The substrate is stabilized via weak alignment and teacher consistency, and training uses question-only replay. AFD achieves state-of-the-art across protocols: 51.6% average accuracy with -1.8% forgetting on domain-incremental VideoQA, ViLCo R@1@0.5 of 29.6% (MQ) and 20.7% (NLQ) with 18.4% stAP@0.25 (VQ), and 39.5% accuracy with -1.6% forgetting on time-incremental iVQA. Overall, AFD offers an explicit, interpretable split between a stable interaction-centered substrate and targeted adaptation.

Wei Liu, Kerem Delikoyun, Qianyu Chen et al.

Off-axis digital holographic microscopy is a high-throughput, label-free imaging technology that provides three-dimensional, high-resolution information about samples, particularly useful in large-scale cellular imaging. However, the hologram reconstruction process poses a significant bottleneck for timely data analysis. To address this challenge, we propose a novel reconstruction approach that integrates deep learning with the physical principles of off-axis holography. We initialized part of the network weights based on the physical principle and then fine-tuned them via weakly supersized learning. Our off-axis hologram network (OAH-Net) retrieves phase and amplitude images with errors that fall within the measurement error range attributable to hardware, and its reconstruction speed significantly surpasses the microscope's acquisition rate. Crucially, OAH-Net demonstrates remarkable external generalization capabilities on unseen samples with distinct patterns and can be seamlessly integrated with other models for downstream tasks to achieve end-to-end real-time hologram analysis. This capability further expands off-axis holography's applications in both biological and medical studies.

Kerem Delikoyun, Qianyu Chen, Liu Wei et al.

While analysing rare blood cell aggregates remains challenging in automated haematology, they could markedly advance label-free functional diagnostics. Conventional flow cytometers efficiently perform cell counting with leukocyte differentials but fail to identify aggregates with flagged results, requiring manual reviews. Quantitative phase imaging flow cytometry captures detailed aggregate morphologies, but clinical use is hampered by massive data storage and offline processing. Incorporating hidden biomarkers into routine haematology panels would significantly improve diagnostics without flagged results. We present RT-HAD, an end-to-end deep learning-based image and data processing framework for off-axis digital holographic microscopy (DHM), which combines physics-consistent holographic reconstruction and detection, representing each blood cell in a graph to recognize aggregates. RT-HAD processes >30 GB of image data on-the-fly with turnaround time of <1.5 min and error rate of 8.9% in platelet aggregate detection, which matches acceptable laboratory error rates of haematology biomarkers and solves the big data challenge for point-of-care diagnostics.