Md. Ahsan Habib

Md. Ahsan Habib, M. A. H. Akhand

Mobility is a key factor in urban life and transport network plays a vital role in mobility. Worse transport network having less mobility is one of the key reasons to decline the living standard in any unplanned mega city. Transport mobility enhancement in an unplanned mega city is always challenging due to various constraints including complex design and high cost involvement. The aim of this thesis is to enhance transport mobility in a megacity introducing a bicycle lane. To design the bicycle lane natural Physarum, brainless single celled multi-nucleated protist, is studied and modified for better optimization. Recently Physarum inspired techniques are drawn significant attention to the construction of effective networks. Exiting Physarum inspired models effectively and efficiently solves different problems including transport network design and modification and implication for bicycle lane is the unique contribution of this study. Central area of Dhaka, the capital city of Bangladesh, is considered to analyze and design the bicycle lane network bypassing primary roads.

Md. Ahsan Habib, M. A. H. Akhand, Md. Abdus Samad Kamal

Microblog, an online-based broadcast medium, is a widely used forum for people to share their thoughts and opinions. Recently, Emotion Recognition (ER) from microblogs is an inspiring research topic in diverse areas. In the machine learning domain, automatic emotion recognition from microblogs is a challenging task, especially, for better outcomes considering diverse content. Emoticon becomes very common in the text of microblogs as it reinforces the meaning of content. This study proposes an emotion recognition scheme considering both the texts and emoticons from microblog data. Emoticons are considered unique expressions of the users' emotions and can be changed by the proper emotional words. The succession of emoticons appearing in the microblog data is preserved and a 1D Convolutional Neural Network (CNN) is employed for emotion classification. The experimental result shows that the proposed emotion recognition scheme outperforms the other existing methods while tested on Twitter data.

Md. Imtyaz Ahmed, Md. Delwar Hossain, Md Mostafizer Rahman et al.

Cancer exhibits diverse and complex phenotypes driven by multifaceted molecular interactions. Recent biomedical research has emphasized the comprehensive study of such diseases by integrating multi-omics datasets (genome, proteome, transcriptome, epigenome). This approach provides an efficient method for identifying genetic variants associated with cancer and offers a deeper understanding of how the disease develops and spreads. However, it is challenging to comprehend complex interactions among the features of multi-omics datasets compared to single omics. In this paper, we analyze lung cancer multi-omics datasets from The Cancer Genome Atlas (TCGA). Using four statistical methods, LIMMA, the T test, Canonical Correlation Analysis (CCA), and the Wilcoxon test, we identified differentially expressed genes across gene expression, DNA methylation, and miRNA expression data. We then integrated these multi-omics data using the Kernel Machine Regression (KMR) approach. Our findings reveal significant interactions among the three omics: gene expression, miRNA expression, and DNA methylation in lung cancer. From our data analysis, we identified 38 genes significantly associated with lung cancer. From our data analysis, we identified 38 genes significantly associated with lung cancer. Among these, eight genes of highest ranking (PDGFRB, PDGFRA, SNAI1, ID1, FGF11, TNXB, ITGB1, ZIC1) were highlighted by rigorous statistical analysis. Furthermore, in silico studies identified three top-ranked potential candidate drugs (Selinexor, Orapred, and Capmatinib) that could play a crucial role in the treatment of lung cancer. These proposed drugs are also supported by the findings of other independent studies, which underscore their potential efficacy in the fight against lung cancer.