Di Huang

Yutong Wu, Di Huang, Wenxuan Shi et al.

Recent advancements in open-source code large language models (LLMs) have been driven by fine-tuning on the data generated from powerful closed-source LLMs, which are expensive to obtain. This paper explores whether it is possible to use a fine-tuned open-source model to generate additional data to augment its instruction-tuning dataset. We make two observations: (1) A code snippet can serve as the response to different instructions. (2) Instruction-tuned code LLMs perform better at translating code into instructions than the reverse. Based on these observations, we propose Inverse-Instruct, a data augmentation technique that uses a fine-tuned LLM to generate additional instructions of code responses from its own training dataset. The additional instruction-response pairs are added to the original dataset, and a stronger code LLM can be obtained by fine-tuning on the augmented dataset. We empirically validate Inverse-Instruct on a range of open-source code models (e.g. CodeLlama-Python and DeepSeek-Coder) and benchmarks (e.g., HumanEval(+), MBPP(+), DS-1000 and MultiPL-E), showing it consistently improves the base models.

Hainan Fang, Yuanbo Wen, Jun Bi et al.

Compilers, while essential, are notoriously complex systems that demand prohibitively expensive human expertise to develop and maintain. The recent advancements in Large Language Models (LLMs) offer a compelling new paradigm: Neural Compilation, which could potentially simplify compiler development for new architectures and facilitate the discovery of innovative optimization techniques. However, several critical obstacles impede its practical adoption. Firstly, a significant lack of dedicated benchmarks and robust evaluation methodologies hinders objective assessment and tracking of progress in the field. Secondly, systematically enhancing the reliability and performance of LLM-generated assembly remains a critical challenge. Addressing these challenges, this paper introduces NeuComBack, a novel benchmark dataset specifically designed for IR-to-assembly compilation. Leveraging this dataset, we first define a foundational Neural Compilation workflow and conduct a comprehensive evaluation of the capabilities of recent frontier LLMs on Neural Compilation, establishing new performance baselines. We further propose a self-evolving prompt optimization method that enables LLMs to iteratively evolve their internal prompt strategies by extracting insights from prior self-debugging traces, thereby enhancing their neural compilation capabilities. Experiments demonstrate that our method significantly improves both the functional correctness and the performance of LLM-generated assembly code. Compared to baseline prompts, the functional correctness rates improved from 44% to 64% on x86_64 and from 36% to 58% on aarch64, respectively. More significantly, among the 16 correctly generated x86_64 programs using our method, 14 (87.5%) surpassed clang-O3 performance.

Heming Zhang, Di Huang, Yixin Chen et al.

The integration of multi-omic data is pivotal for understanding complex diseases, but its high dimensionality and noise present significant challenges. Graph Neural Networks (GNNs) offer a robust framework for analyzing large-scale signaling pathways and protein-protein interaction networks, yet they face limitations in expressivity when capturing intricate biological relationships. To address this, we propose Graph Sequence Language Model (GraphSeqLM), a framework that enhances GNNs with biological sequence embeddings generated by Large Language Models (LLMs). These embeddings encode structural and biological properties of DNA, RNA, and proteins, augmenting GNNs with enriched features for analyzing sample-specific multi-omic data. By integrating topological, sequence-derived, and biological information, GraphSeqLM demonstrates superior predictive accuracy and outperforms existing methods, paving the way for more effective multi-omic data integration in precision medicine.