Xinyue Han

Haowei Yang, Ziyu Shen, Junli Shao et al.

Timely identification and accurate risk stratification of cardiovascular disease (CVD) remain essential for reducing global mortality. While existing prediction models primarily leverage structured data, unstructured clinical notes contain valuable early indicators. This study introduces a novel LLM-augmented clinical NLP pipeline that employs domain-adapted large language models for symptom extraction, contextual reasoning, and correlation from free-text reports. Our approach integrates cardiovascular-specific fine-tuning, prompt-based inference, and entity-aware reasoning. Evaluations on MIMIC-III and CARDIO-NLP datasets demonstrate improved performance in precision, recall, F1-score, and AUROC, with high clinical relevance (kappa = 0.82) assessed by cardiologists. Challenges such as contextual hallucination, which occurs when plausible information contracts with provided source, and temporal ambiguity, which is related with models struggling with chronological ordering of events are addressed using prompt engineering and hybrid rule-based verification. This work underscores the potential of LLMs in clinical decision support systems (CDSS), advancing early warning systems and enhancing the translation of patient narratives into actionable risk assessments.

Yushang Zhao, Haotian Lyu, Yike Peng et al.

The incessant advent of online services demands high speed and efficient recommender systems (ReS) that can maintain real-time performance along with processing very complex user-item interactions. The present study, therefore, considers computational bottlenecks involved in hybrid Graph Neural Network (GNN) and Large Language Model (LLM)-based ReS with the aim optimizing their inference latency and training efficiency. An extensive methodology was used: hybrid GNN-LLM integrated architecture-optimization strategies(quantization, LoRA, distillation)-hardware acceleration (FPGA, DeepSpeed)-all under R 4.4.2. Experimental improvements were significant, with the optimal Hybrid + FPGA + DeepSpeed configuration reaching 13.6% more accuracy (NDCG@10: 0.75) at 40-60ms of latency, while LoRA brought down training time by 66% (3.8 hours) in comparison to the non-optimized baseline. Irrespective of domain, such as accuracy or efficiency, it can be established that hardware-software co-design and parameter-efficient tuning permit hybrid models to outperform GNN or LLM approaches implemented independently. It recommends the use of FPGA as well as LoRA for real-time deployment. Future work should involve federated learning along with advanced fusion architectures for better scalability and privacy preservation. Thus, this research marks the fundamental groundwork concerning next-generation ReS balancing low-latency response with cutting-edge personalization.