Amr AbdelFatah Ahmed

Aasim Bin Saleem, Amr Ahmed, Ardhendu Behera et al.

Immunohistochemistry (IHC) is essential for assessing specific immune biomarkers like Human Epidermal growth-factor Receptor 2 (HER2) in breast cancer. However, the traditional protocols of obtaining IHC stains are resource-intensive, time-consuming, and prone to structural damages. Virtual staining has emerged as a scalable alternative, but it faces significant challenges in preserving fine-grained cellular structures while accurately translating biochemical expressions. Current state-of-the-art methods still rely on Generative Adversarial Networks (GANs) or standard convolutional U-Net diffusion models that often struggle with "structure and staining trade-offs". The generated samples are either structurally relevant but blurry, or texturally realistic but have artifacts that compromise their diagnostic use. In this paper, we introduce HistDiT, a novel latent conditional Diffusion Transformer (DiT) architecture that establishes a new benchmark for visual fidelity in virtual histological staining. The novelty introduced in this work is, a) the Dual-Stream Conditioning strategy that explicitly maintains a balance between spatial constraints via VAE-encoded latents and semantic phenotype guidance via UNI embeddings; b) the multi-objective loss function that contributes to sharper images with clear morphological structure; and c) the use of the Structural Correlation Metric (SCM) to focus on the core morphological structure for precise assessment of sample quality. Consequently, our model outperforms existing baselines, as demonstrated through rigorous quantitative and qualitative evaluations.

Somnath Basu Roy Chowdhury, Rahul Kidambi, Avinava Dubey et al.

Machine unlearning is the process of efficiently removing specific information from a trained machine learning model without retraining from scratch. Existing unlearning methods, which often provide provable guarantees, typically involve retraining a subset of model parameters based on a forget set. While these approaches show promise in certain scenarios, their underlying assumptions are often challenged in real-world applications -- particularly when applied to generative models. Furthermore, updating parameters using these unlearning procedures often degrades the general-purpose capabilities the model acquired during pre-training. Motivated by these shortcomings, this paper considers the paradigm of inference time unlearning -- wherein, the generative model is equipped with an (approximately correct) verifier that judges whether the model's response satisfies appropriate unlearning guarantees. This paper introduces a framework that iteratively refines the quality of the generated responses using feedback from the verifier without updating the model parameters. The proposed framework leverages conformal prediction to reduce computational overhead and provide distribution-free unlearning guarantees. This paper's approach significantly outperforms existing state-of-the-art methods, reducing unlearning error by up to 93% across challenging unlearning benchmarks.

Mohammed Rahman Sherif Khan Mohammad, Ardhendu Behera, Sandip Pradhan et al.

Recent adapter-based CLIP tuning (e.g., Tip-Adapter) is a strong few-shot learner, achieving efficiency by caching support features for fast prototype matching. However, these methods rely on global uni-modal feature vectors, overlooking fine-grained patch relations and their structural alignment with class text. To bridge this gap without incurring inference costs, we introduce a novel asymmetric training-only framework. Instead of altering the lightweight adapter, we construct a high-capacity auxiliary Heterogeneous Graph Teacher that operates solely during training. This teacher (i) integrates multi-scale visual patches and text prompts into a unified graph, (ii) performs deep cross-modal reasoning via a Modality-aware Graph Transformer (MGT), and (iii) applies discriminative node filtering to extract high-fidelity class features. Crucially, we employ a cache-aware dual-objective strategy to supervise this relational knowledge directly into the Tip-Adapter's key-value cache, effectively upgrading the prototypes while the graph teacher is discarded at test time. Thus, inference remains identical to Tip-Adapter with zero extra latency or memory. Across standard 1-16-shot benchmarks, our method consistently establishes a new state-of-the-art. Ablations confirm that the auxiliary graph supervision, text-guided reasoning, and node filtering are the essential ingredients for robust few-shot adaptation. Code is available at https://github.com/MR-Sherif/TOGA.git.