Zhe Xu

Jiashun Chen, Donghuan Lu, Yu Zhang et al.

Recently, deep-learning-based approaches have been widely studied for deformable image registration task. However, most efforts directly map the composite image representation to spatial transformation through the convolutional neural network, ignoring its limited ability to capture spatial correspondence. On the other hand, Transformer can better characterize the spatial relationship with attention mechanism, its long-range dependency may be harmful to the registration task, where voxels with too large distances are unlikely to be corresponding pairs. In this study, we propose a novel Deformer module along with a multi-scale framework for the deformable image registration task. The Deformer module is designed to facilitate the mapping from image representation to spatial transformation by formulating the displacement vector prediction as the weighted summation of several bases. With the multi-scale framework to predict the displacement fields in a coarse-to-fine manner, superior performance can be achieved compared with traditional and learning-based approaches. Comprehensive experiments on two public datasets are conducted to demonstrate the effectiveness of the proposed Deformer module as well as the multi-scale framework.

Xingjian Zhao, Zhe Xu, Qinyuan Cheng et al.

Spoken dialogue systems often rely on cascaded pipelines that transcribe, process, and resynthesize speech. While effective, this design discards paralinguistic cues and limits expressivity. Recent end-to-end methods reduce latency and better preserve these cues, yet still rely on text intermediates, creating a fundamental bottleneck. We present MOSS-Speech, a true speech-to-speech large language model that directly understands and generates speech without relying on text guidance. Our approach combines a modality-based layer-splitting architecture with a frozen pre-training strategy, preserving the reasoning and knowledge of pretrained text LLMs while adding native speech capabilities. Experiments show that our model achieves state-of-the-art results in spoken question answering and delivers comparable speech-to-speech performance relative to existing text-guided systems, while still maintaining competitive text performance. By narrowing the gap between text-guided and direct speech generation, our work establishes a new paradigm for expressive and efficient end-to-end speech interaction.

Zhe Xu, Xiaoming Duan

Pandemics can bring a range of devastating consequences to public health and the world economy. Identifying the most effective control strategies has been the imperative task all around the world. Various public health control strategies have been proposed and tested against pandemic diseases (e.g., COVID-19). We study two specific pandemic control models: the susceptible, exposed, infectious, recovered (SEIR) model with vaccination control; and the SEIR model with shield immunity control. We express the pandemic control requirement in metric temporal logic (MTL) formulas. We then develop an iterative approach for synthesizing the optimal control strategies with MTL specifications. We provide simulation results in two different scenarios for robust control of the COVID-19 pandemic: one for vaccination control, and another for shield immunity control, with the model parameters estimated from data in Lombardy, Italy. The results show that the proposed synthesis approach can generate control inputs such that the time-varying numbers of individuals in each category (e.g., infectious, immune) satisfy the MTL specifications with robustness against initial state and parameter uncertainties.