Yi Pan

Jiaqi Wang, Hanqi Jiang, Yiheng Liu et al.

In an era defined by the explosive growth of data and rapid technological advancements, Multimodal Large Language Models (MLLMs) stand at the forefront of artificial intelligence (AI) systems. Designed to seamlessly integrate diverse data types-including text, images, videos, audio, and physiological sequences-MLLMs address the complexities of real-world applications far beyond the capabilities of single-modality systems. In this paper, we systematically sort out the applications of MLLM in multimodal tasks such as natural language, vision, and audio. We also provide a comparative analysis of the focus of different MLLMs in the tasks, and provide insights into the shortcomings of current MLLMs, and suggest potential directions for future research. Through these discussions, this paper hopes to provide valuable insights for the further development and application of MLLM.

Fangyu Zhang, Yanjie Wei, Jin Liu et al.

The development of noninvasive brain imaging such as resting-state functional magnetic resonance imaging (rs-fMRI) and its combination with AI algorithm provides a promising solution for the early diagnosis of Autism spectrum disorder (ASD). However, the performance of the current ASD classification based on rs-fMRI still needs to be improved. This paper introduces a classification framework to aid ASD diagnosis based on rs-fMRI. In the framework, we proposed a novel filter feature selection method based on the difference between step distribution curves (DSDC) to select remarkable functional connectivities (FCs) and utilized a multilayer perceptron (MLP) which was pretrained by a simplified Variational Autoencoder (VAE) for classification. We also designed a pipeline consisting of a normalization procedure and a modified hyperbolic tangent (tanh) activation function to replace the original tanh function, further improving the model accuracy. Our model was evaluated by 10 times 10-fold cross-validation and achieved an average accuracy of 78.12%, outperforming the state-of-the-art methods reported on the same dataset. Given the importance of sensitivity and specificity in disease diagnosis, two constraints were designed in our model which can improve the model's sensitivity and specificity by up to 9.32% and 10.21%, respectively. The added constraints allow our model to handle different application scenarios and can be used broadly.

Sohan Shankar, Yi Pan, Hanqi Jiang et al.

This position and survey paper identifies the emerging convergence of neuroscience, artificial general intelligence (AGI), and neuromorphic computing toward a unified research paradigm. Using a framework grounded in brain physiology, we highlight how synaptic plasticity, sparse spike-based communication, and multimodal association provide design principles for next-generation AGI systems that potentially combine both human and machine intelligences. The review traces this evolution from early connectionist models to state-of-the-art large language models, demonstrating how key innovations like transformer attention, foundation-model pre-training, and multi-agent architectures mirror neurobiological processes like cortical mechanisms, working memory, and episodic consolidation. We then discuss emerging physical substrates capable of breaking the von Neumann bottleneck to achieve brain-scale efficiency in silicon: memristive crossbars, in-memory compute arrays, and emerging quantum and photonic devices. There are four critical challenges at this intersection: 1) integrating spiking dynamics with foundation models, 2) maintaining lifelong plasticity without catastrophic forgetting, 3) unifying language with sensorimotor learning in embodied agents, and 4) enforcing ethical safeguards in advanced neuromorphic autonomous systems. This combined perspective across neuroscience, computation, and hardware offers an integrative agenda for in each of these fields.

Ruimin Ma, Yanlin Wang, Yanjie Wei et al.

Accurate diagnosis of autism spectrum disorder (ASD) based on neuroimaging data has significant implications, as extracting useful information from neuroimaging data for ASD detection is challenging. Even though machine learning techniques have been leveraged to improve the information extraction from neuroimaging data, the varying data quality caused by different meta-data conditions (i.e., data collection strategies) limits the effective information that can be extracted, thus leading to data-dependent predictive accuracies in ASD detection, which can be worse than random guess in some cases. In this work, we systematically investigate the impact of three kinds of meta-data on the predictive accuracy of classifying ASD based on structural MRI collected from 20 different sites, where meta-data conditions vary.

Xiaoqing Zhang, Qiushi Nie, Zunjie Xiao et al.

Spatial pooling (SP) and cross-channel pooling (CCP) operators have been applied to aggregate spatial features and pixel-wise features from feature maps in deep neural networks (DNNs), respectively. Their main goal is to reduce computation and memory overhead without visibly weakening the performance of DNNs. However, SP often faces the problem of losing the subtle feature representations, while CCP has a high possibility of ignoring salient feature representations, which may lead to both miscalibration of confidence issues and suboptimal medical classification results. To address these problems, we propose a novel dual-view framework, the first to systematically investigate the relative roles of SP and CCP by analyzing the difference between spatial features and pixel-wise features. Based on this framework, we propose a new pooling method, termed dual-view pyramid pooling (DVPP), to aggregate multi-scale dual-view features. DVPP aims to boost both medical image classification and confidence calibration performance by fully leveraging the merits of SP and CCP operators from a dual-axis perspective. Additionally, we discuss how to fulfill DVPP with five parameter-free implementations. Extensive experiments on six 2D/3D medical image classification tasks show that our DVPP surpasses state-of-the-art pooling methods in terms of medical image classification results and confidence calibration across different DNNs.

Peng Shu, Huaqin Zhao, Hanqi Jiang et al.

Large language models and multimodal large language models have revolutionized artificial intelligence recently. An increasing number of regions are now embracing these advanced technologies. Within this context, robot coding education is garnering increasing attention. To teach young children how to code and compete in robot challenges, large language models are being utilized for robot code explanation, generation, and modification. In this paper, we highlight an important trend in robot coding education. We test several mainstream large language models on both traditional coding tasks and the more challenging task of robot code generation, which includes block diagrams. Our results show that GPT-4V outperforms other models in all of our tests but struggles with generating block diagram images.

Huaqin Zhao, Jiaxi Li, Yi Pan et al.

Fine-tuning large language models (LLMs) poses significant memory challenges, as the back-propagation process demands extensive resources, especially with growing model sizes. Recent work, MeZO, addresses this issue using a zeroth-order (ZO) optimization method, which reduces memory consumption by matching the usage to the inference phase. However, MeZO experiences slow convergence due to varying curvatures across model parameters. To overcome this limitation, we introduce HELENE, a novel scalable and memory-efficient optimizer that integrates annealed A-GNB gradients with a diagonal Hessian estimation and layer-wise clipping, serving as a second-order pre-conditioner. This combination allows for faster and more stable convergence. Our theoretical analysis demonstrates that HELENE improves convergence rates, particularly for models with heterogeneous layer dimensions, by reducing the dependency on the total parameter space dimension. Instead, the method scales with the largest layer dimension, making it highly suitable for modern LLM architectures. Experimental results on RoBERTa-large and OPT-1.3B across multiple tasks show that HELENE achieves up to a 20x speedup compared to MeZO, with average accuracy improvements of 1.5%. Furthermore, HELENE remains compatible with both full parameter tuning and parameter-efficient fine-tuning (PEFT), outperforming several state-of-the-art optimizers. The codes will be released after reviewing.

Qingdong He, Xueqin Chen, Chaoyi Wang et al.

Instruction-based image editing (IIE) has advanced rapidly with the success of diffusion models. However, existing efforts primarily focus on simple and explicit instructions to execute editing operations such as adding, deleting, moving, or swapping objects. They struggle to handle more complex implicit hypothetical instructions that require deeper reasoning to infer plausible visual changes and user intent. Additionally, current datasets provide limited support for training and evaluating reasoning-aware editing capabilities. Architecturally, these methods also lack mechanisms for fine-grained detail extraction that support such reasoning. To address these limitations, we propose Reason50K, a large-scale dataset specifically curated for training and evaluating hypothetical instruction reasoning image editing, along with ReasonBrain, a novel framework designed to reason over and execute implicit hypothetical instructions across diverse scenarios. Reason50K includes over 50K samples spanning four key reasoning scenarios: Physical, Temporal, Causal, and Story reasoning. ReasonBrain leverages Multimodal Large Language Models (MLLMs) for editing guidance generation and a diffusion model for image synthesis, incorporating a Fine-grained Reasoning Cue Extraction (FRCE) module to capture detailed visual and textual semantics essential for supporting instruction reasoning. To mitigate the semantic loss, we further introduce a Cross-Modal Enhancer (CME) that enables rich interactions between the fine-grained cues and MLLM-derived features. Extensive experiments demonstrate that ReasonBrain consistently outperforms state-of-the-art baselines on reasoning scenarios while exhibiting strong zero-shot generalization to conventional IIE tasks. Our dataset and code will be released publicly.

Yi Pan, Hanqi Jiang, Junhao Chen et al.

Neuromorphic computing has emerged as a promising energy-efficient alternative to traditional artificial intelligence, predominantly utilizing spiking neural networks (SNNs) implemented on neuromorphic hardware. Significant advancements have been made in SNN-based convolutional neural networks (CNNs) and Transformer architectures. However, neuromorphic computing for the medical imaging domain remains underexplored. In this study, we introduce EG-SpikeFormer, an SNN architecture tailored for clinical tasks that incorporates eye-gaze data to guide the model's attention to the diagnostically relevant regions in medical images. Our developed approach effectively addresses shortcut learning issues commonly observed in conventional models, especially in scenarios with limited clinical data and high demands for model reliability, generalizability, and transparency. Our EG-SpikeFormer not only demonstrates superior energy efficiency and performance in medical image prediction tasks but also enhances clinical relevance through multi-modal information alignment. By incorporating eye-gaze data, the model improves interpretability and generalization, opening new directions for applying neuromorphic computing in healthcare.

Yanjie Pan, Qingdong He, Lidong Wang et al.

Video virtual try-on aims to replace the clothing of a person in a video with a target garment. Current dual-branch architectures have achieved significant success in diffusion models based on the U-Net; however, adapting them to diffusion models built upon the Diffusion Transformer remains challenging. Initially, introducing latent space features from the garment reference branch requires adding or modifying the backbone network, leading to a large number of trainable parameters. Subsequently, the latent space features of garments lack inherent temporal characteristics and thus require additional learning. To address these challenges, we propose a novel approach, OIE (Once is Enough), a virtual try-on strategy based on first-frame clothing replacement: specifically, we employ an image-based clothing transfer model to replace the clothing in the initial frame, and then, under the content control of the edited first frame, utilize pose and mask information to guide the temporal prior of the video generation model in synthesizing the remaining frames sequentially. Experiments show that our method achieves superior parameter efficiency and computational efficiency while still maintaining leading performance under these constraints.

Qiankun Zuo, Baiying Lei, Ning Zhong et al.

Integrating the brain structural and functional connectivity features is of great significance in both exploring brain science and analyzing cognitive impairment clinically. However, it remains a challenge to effectively fuse structural and functional features in exploring the brain network. In this paper, a novel brain structure-function fusing-representation learning (BSFL) model is proposed to effectively learn fused representation from diffusion tensor imaging (DTI) and resting-state functional magnetic resonance imaging (fMRI) for mild cognitive impairment (MCI) analysis. Specifically, the decomposition-fusion framework is developed to first decompose the feature space into the union of the uniform and the unique spaces for each modality, and then adaptively fuse the decomposed features to learn MCI-related representation. Moreover, a knowledge-aware transformer module is designed to automatically capture local and global connectivity features throughout the brain. Also, a uniform-unique contrastive loss is further devised to make the decomposition more effective and enhance the complementarity of structural and functional features. The extensive experiments demonstrate that the proposed model achieves better performance than other competitive methods in predicting and analyzing MCI. More importantly, the proposed model could be a potential tool for reconstructing unified brain networks and predicting abnormal connections during the degenerative processes in MCI.

Zhipeng Cai, Zuobin Xiong, Honghui Xu et al.

Generative Adversarial Networks (GAN) have promoted a variety of applications in computer vision, natural language processing, etc. due to its generative model's compelling ability to generate realistic examples plausibly drawn from an existing distribution of samples. GAN not only provides impressive performance on data generation-based tasks but also stimulates fertilization for privacy and security oriented research because of its game theoretic optimization strategy. Unfortunately, there are no comprehensive surveys on GAN in privacy and security, which motivates this survey paper to summarize those state-of-the-art works systematically. The existing works are classified into proper categories based on privacy and security functions, and this survey paper conducts a comprehensive analysis of their advantages and drawbacks. Considering that GAN in privacy and security is still at a very initial stage and has imposed unique challenges that are yet to be well addressed, this paper also sheds light on some potential privacy and security applications with GAN and elaborates on some future research directions.

Thosini Bamunu Mudiyanselage, Nipuna Senanayake, Chunyan Ji et al.

The novel corona virus (Covid-19) has introduced significant challenges due to its rapid spreading nature through respiratory transmission. As a result, there is a huge demand for Artificial Intelligence (AI) based quick disease diagnosis methods as an alternative to high demand tests such as Polymerase Chain Reaction (PCR). Chest X-ray (CXR) Image analysis is such cost-effective radiography technique due to resource availability and quick screening. But, a sufficient and systematic data collection that is required by complex deep leaning (DL) models is more difficult and hence there are recent efforts that utilize transfer learning to address this issue. Still these transfer learnt models suffer from lack of generalization and increased bias to the training dataset resulting poor performance for unseen data. Limited correlation of the transferred features from the pre-trained model to a specific medical imaging domain like X-ray and overfitting on fewer data can be reasons for this circumstance. In this work, we propose a novel Graph Convolution Neural Network (GCN) that is capable of identifying bio-markers of Covid-19 pneumonia from CXR images and meta information about patients. The proposed method exploits important relational knowledge between data instances and their features using graph representation and applies convolution to learn the graph data which is not possible with conventional convolution on Euclidean domain. The results of extensive experiments of proposed model on binary (Covid vs normal) and three class (Covid, normal, other pneumonia) classification problems outperform different benchmark transfer learnt models, hence overcoming the aforementioned drawbacks.

Chunyan Ji, Yi Pan

From crying to babbling and then to speech, infant's vocal tract goes through anatomic restructuring. In this paper, we propose a non-invasive fast method of using infant cry signals with convolutional neural network (CNN) based age classification to diagnose the abnormality of the vocal tract development as early as 4-month age. We study F0, F1, F2, and spectrograms and relate them to the postnatal development of infant vocalization. A novel CNN based age classification is performed with binary age pairs to discover the pattern and tendency of the vocal tract changes. The effectiveness of this approach is evaluated on Baby2020 with healthy infant cries and Baby Chillanto database with pathological infant cries. The results show that our approach yields 79.20% accuracy for healthy cries, 84.80% for asphyxiated cries, and 91.20% for deaf cries. Our method first reveals that infants' vocal tract develops to a certain level at 4-month age and infants can start controlling the vocal folds to produce discontinuous cry sounds leading to babbling. Early diagnosis of growth abnormality of the vocal tract can help parents keep vigilant and adopt medical treatment or training therapy for their infants as early as possible.

Chunyan Ji, Ming Chen, Bin Li et al.

We propose an approach of graph convolutional networks for robust infant cry classification. We construct non-fully connected graphs based on the similarities among the relevant nodes in both supervised and semi-supervised node classification with convolutional neural networks to consider the short-term and long-term effects of infant cry signals related to inner-class and inter-class messages. The approach captures the diversity of variations within infant cries, especially for limited training samples. The effectiveness of this approach is evaluated on Baby Chillanto Database and Baby2020 database. With as limited as 20% of labeled training data, our model outperforms that of CNN model with 80% labeled training data and the accuracy stably improves as the number of labeled training samples increases. The best results give significant improvements of 7.36% and 3.59% compared with the results of the CNN models on Baby Chillanto database and Baby2020 database respectively.

Xueli Xiao, Chunyan Ji, Thosini Bamunu Mudiyanselage et al.

Deep learning has gained great success in various classification tasks. Typically, deep learning models learn underlying features directly from data, and no underlying relationship between classes are included. Similarity between classes can influence the performance of classification. In this article, we propose a method that incorporates class similarity knowledge into convolutional neural networks models using a graph convolution layer. We evaluate our method on two benchmark image datasets: MNIST and CIFAR10, and analyze the results on different data and model sizes. Experimental results show that our model can improve classification accuracy, especially when the amount of available data is small.

Ming Yan, Xueli Xiao, Joey Tianyi Zhou et al.

Deep neural networks have achieved great success both in computer vision and natural language processing tasks. However, mostly state-of-art methods highly rely on external training or computing to improve the performance. To alleviate the external reliance, we proposed a gradient enhancement approach, conducted by the short circuit neural connections, to improve the gradient learning of deep neural networks. The proposed short circuit is a unidirectional connection that single back propagates the sensitive from the deep layer to the shallows. Moreover, the short circuit formulates to be a gradient truncation of its crossing layers which can plug into the backbone deep neural networks without introducing external training parameters. Extensive experiments demonstrate deep neural networks with our short circuit gain a large margin over the baselines on both computer vision and natural language processing tasks.

Thosini Bamunu Mudiyanselage, Xiujuan Lei, Nipuna Senanayake et al.

Graphs can be used to effectively represent complex data structures. Learning these irregular data in graphs is challenging and still suffers from shallow learning. Applying deep learning on graphs has recently showed good performance in many applications in social analysis, bioinformatics etc. A message passing graph convolution network is such a powerful method which has expressive power to learn graph structures. Meanwhile, circRNA is a type of non-coding RNA which plays a critical role in human diseases. Identifying the associations between circRNAs and diseases is important to diagnosis and treatment of complex diseases. However, there are limited number of known associations between them and conducting biological experiments to identify new associations is time consuming and expensive. As a result, there is a need of building efficient and feasible computation methods to predict potential circRNA-disease associations. In this paper, we propose a novel graph convolution network framework to learn features from a graph built with multi-source similarity information to predict circRNA-disease associations. First we use multi-source information of circRNA similarity, disease and circRNA Gaussian Interaction Profile (GIP) kernel similarity to extract the features using first graph convolution. Then we predict disease associations for each circRNA with second graph convolution. Proposed framework with five-fold cross validation on various experiments shows promising results in predicting circRNA-disease association and outperforms other existing methods.

Yang Li, Yi Pan

In recent years, machine learning and deep learning have become popular methods for financial data analysis, including financial textual data, numerical data, and graphical data. This paper proposes to use sentiment analysis to extract useful information from multiple textual data sources and a blending ensemble deep learning model to predict future stock movement. The blending ensemble model contains two levels. The first level contains two Recurrent Neural Networks (RNNs), one Long-Short Term Memory network (LSTM) and one Gated Recurrent Units network (GRU), followed by a fully connected neural network as the second level model. The RNNs, LSTM, and GRU models can effectively capture the time-series events in the input data, and the fully connected neural network is used to ensemble several individual prediction results to further improve the prediction accuracy. The purpose of this work is to explain our design philosophy and show that ensemble deep learning technologies can truly predict future stock price trends more effectively and can better assist investors in making the right investment decision than other traditional methods.

Yutong Gao, Yi Pan

Machine learning techniques are immensely deployed in both industry and academy. Recent studies indicate that machine learning models used for classification tasks are vulnerable to adversarial examples, which limits the usage of applications in the fields with high precision requirements. We propose a new approach called Feature Map Denoising to detect the adversarial inputs and show the performance of detection on the mixed dataset consisting of adversarial examples generated by different attack algorithms, which can be used to associate with any pre-trained DNNs at a low cost. Wiener filter is also introduced as the denoise algorithm to the defense model, which can further improve performance. Experimental results indicate that good accuracy of detecting the adversarial examples can be achieved through our Feature Map Denoising algorithm.

Xueli Xiao, Ming Yan, Sunitha Basodi et al.

Convolutional Neural Networks (CNN) have gained great success in many artificial intelligence tasks. However, finding a good set of hyperparameters for a CNN remains a challenging task. It usually takes an expert with deep knowledge, and trials and errors. Genetic algorithms have been used in hyperparameter optimizations. However, traditional genetic algorithms with fixed-length chromosomes may not be a good fit for optimizing deep learning hyperparameters, because deep learning models have variable number of hyperparameters depending on the model depth. As the depth increases, the number of hyperparameters grows exponentially, and searching becomes exponentially harder. It is important to have an efficient algorithm that can find a good model in reasonable time. In this article, we propose to use a variable length genetic algorithm (GA) to systematically and automatically tune the hyperparameters of a CNN to improve its performance. Experimental results show that our algorithm can find good CNN hyperparameters efficiently. It is clear from our experiments that if more time is spent on optimizing the hyperparameters, better results could be achieved. Theoretically, if we had unlimited time and CPU power, we could find the optimized hyperparameters and achieve the best results in the future.

Sunitha Basodi, Chunyan Ji, Haiping Zhang et al.

Improving performance of deep learning models and reducing their training times are ongoing challenges in deep neural networks. There are several approaches proposed to address these challenges one of which is to increase the depth of the neural networks. Such deeper networks not only increase training times, but also suffer from vanishing gradients problem while training. In this work, we propose gradient amplification approach for training deep learning models to prevent vanishing gradients and also develop a training strategy to enable or disable gradient amplification method across several epochs with different learning rates. We perform experiments on VGG-19 and resnet (Resnet-18 and Resnet-34) models, and study the impact of amplification parameters on these models in detail. Our proposed approach improves performance of these deep learning models even at higher learning rates, thereby allowing these models to achieve higher performance with reduced training time.

Zeng Yu, Tianrui Li, Ning Yu et al.

This paper aims to develop a new architecture that can make full use of the feature maps of convolutional networks. To this end, we study a number of methods for video-based person re-identification and make the following findings: 1) Max-pooling only focuses on the maximum value of a receptive field, wasting a lot of information. 2) Networks with different streams even including the one with the worst performance work better than networks with same streams, where each one has the best performance alone. 3) A full connection layer at the end of convolutional networks is not necessary. Based on these studies, we propose a new convolutional architecture termed Three-Stream Convolutional Networks (TSCN). It first uses different streams to learn different aspects of feature maps for attentive spatio-temporal fusion of video, and then merges them together to study some union features. To further utilize the feature maps, two architectures are designed by using the strategies of multi-scale and upsampling. Comparative experiments on iLIDS-VID, PRID-2011 and MARS datasets illustrate that the proposed architectures are significantly better for feature extraction than the state-of-the-art models.