Chongyu Wang

Xinyan Wang, Ting Jia, Chongyu Wang et al. · tsinghua

Accurate identification of disease genes has consistently been one of the keys to decoding a disease's molecular mechanism. Most current approaches focus on constructing biological networks and utilizing machine learning, especially, deep learning to identify disease genes, but ignore the complex relations between entities in the biological knowledge graph. In this paper, we construct a biological knowledge graph centered on diseases and genes, and develop an end-to-end Knowledge graph completion model for Disease Gene Prediction using interactional tensor decomposition (called KDGene). KDGene introduces an interaction module between the embeddings of entities and relations to tensor decomposition, which can effectively enhance the information interaction in biological knowledge. Experimental results show that KDGene significantly outperforms state-of-the-art algorithms. Furthermore, the comprehensive biological analysis of the case of diabetes mellitus confirms KDGene's ability for identifying new and accurate candidate genes. This work proposes a scalable knowledge graph completion framework to identify disease candidate genes, from which the results are promising to provide valuable references for further wet experiments.

Yana Wei, Zeen Chi, Chongyu Wang et al.

In open-world environments, human-object interactions (HOIs) evolve continuously, challenging conventional closed-world HOI detection models. Inspired by humans' ability to progressively acquire knowledge, we explore incremental HOI detection (IHOID) to develop agents capable of discerning human-object relations in such dynamic environments. This setup confronts not only the common issue of catastrophic forgetting in incremental learning but also distinct challenges posed by interaction drift and detecting zero-shot HOI combinations with sequentially arriving data. Therefore, we propose a novel exemplar-free incremental relation distillation (IRD) framework. IRD decouples the learning of objects and relations, and introduces two unique distillation losses for learning invariant relation features across different HOI combinations that share the same relation. Extensive experiments on HICO-DET and V-COCO datasets demonstrate the superiority of our method over state-of-the-art baselines in mitigating forgetting, strengthening robustness against interaction drift, and generalization on zero-shot HOIs. Code is available at \href{https://github.com/weiyana/ContinualHOI}{this HTTP URL}

Tao Liu, Chongyu Wang, Rongjie Li et al.

While Multimodal Large Language Models (MLLMs) have advanced GUI navigation agents, current approaches face limitations in cross-domain generalization and effective history utilization. We present a reasoning-enhanced framework that systematically integrates structured reasoning, action prediction, and history summarization. The structured reasoning component generates coherent Chain-of-Thought analyses combining progress estimation and decision reasoning, which inform both immediate action predictions and compact history summaries for future steps. Based on this framework, we train a GUI agent, \textbf{GUI-Rise}, through supervised fine-tuning on pseudo-labeled trajectories and reinforcement learning with Group Relative Policy Optimization (GRPO). This framework employs specialized rewards, including a history-aware objective, directly linking summary quality to subsequent action performance. Comprehensive evaluations on standard benchmarks demonstrate state-of-the-art results under identical training data conditions, with particularly strong performance in out-of-domain scenarios. These findings validate our framework's ability to maintain robust reasoning and generalization across diverse GUI navigation tasks. Code is available at https://leon022.github.io/GUI-Rise.

Tao Liu, Rongjie Li, Chongyu Wang et al.

Open-vocabulary Scene Graph Generation (OV-SGG) overcomes the limitations of the closed-set assumption by aligning visual relationship representations with open-vocabulary textual representations. This enables the identification of novel visual relationships, making it applicable to real-world scenarios with diverse relationships. However, existing OV-SGG methods are constrained by fixed text representations, limiting diversity and accuracy in image-text alignment. To address these challenges, we propose the Relation-Aware Hierarchical Prompting (RAHP) framework, which enhances text representation by integrating subject-object and region-specific relation information. Our approach utilizes entity clustering to address the complexity of relation triplet categories, enabling the effective integration of subject-object information. Additionally, we utilize a large language model (LLM) to generate detailed region-aware prompts, capturing fine-grained visual interactions and improving alignment between visual and textual modalities. RAHP also introduces a dynamic selection mechanism within Vision-Language Models (VLMs), which adaptively selects relevant text prompts based on the visual content, reducing noise from irrelevant prompts. Extensive experiments on the Visual Genome and Open Images v6 datasets demonstrate that our framework consistently achieves state-of-the-art performance, demonstrating its effectiveness in addressing the challenges of open-vocabulary scene graph generation. The code is available at: https://github.com/Leon022/RAHP

Haodong Wang, Chongyu Wang, Yinghui Quan et al.

Expanding the receptive field in a deep learning model for large-scale 3D point cloud segmentation is an effective technique for capturing rich contextual information, which consequently enhances the network's ability to learn meaningful features. However, this often leads to increased computational complexity and risk of overfitting, challenging the efficiency and effectiveness of the learning paradigm. To address these limitations, we propose the Local Split Attention Pooling (LSAP) mechanism to effectively expand the receptive field through a series of local split operations, thus facilitating the acquisition of broader contextual knowledge. Concurrently, it optimizes the computational workload associated with attention-pooling layers to ensure a more streamlined processing workflow. Based on LSAP, a Parallel Aggregation Enhancement (PAE) module is introduced to enable parallel processing of data using both 2D and 3D neighboring information to further enhance contextual representations within the network. In light of the aforementioned designs, we put forth a novel framework, designated as LSNet, for large-scale point cloud semantic segmentation. Extensive evaluations demonstrated the efficacy of seamlessly integrating the proposed PAE module into existing frameworks, yielding significant improvements in mean intersection over union (mIoU) metrics, with a notable increase of up to 11%. Furthermore, LSNet demonstrated superior performance compared to state-of-the-art semantic segmentation networks on three benchmark datasets, including S3DIS, Toronto3D, and SensatUrban. It is noteworthy that our method achieved a substantial speedup of approximately 38.8% compared to those employing similar-sized receptive fields, which serves to highlight both its computational efficiency and practical utility in real-world large-scale scenes.

Chongyu Wang, Kunlei Jing, Jihua Zhu et al.

Open-vocabulary semantic segmentation enables models to recognize and segment objects from arbitrary natural language descriptions, offering the flexibility to handle novel, fine-grained, or functionally defined categories beyond fixed label sets. While this capability is crucial for large-scale urban point clouds that support applications such as digital twins, smart city management, and urban analytics, it remains largely unexplored in this domain. The main obstacles are the frequent absence of high-quality, well-aligned multi-view imagery in large-scale urban point cloud datasets and the poor generalization of existing three-dimensional (3D) segmentation pipelines across diverse urban environments with substantial variation in geometry, scale, and appearance. To address these challenges, we present OpenUrban3D, the first 3D open-vocabulary semantic segmentation framework for large-scale urban scenes that operates without aligned multi-view images, pre-trained point cloud segmentation networks, or manual annotations. Our approach generates robust semantic features directly from raw point clouds through multi-view, multi-granularity rendering, mask-level vision-language feature extraction, and sample-balanced fusion, followed by distillation into a 3D backbone model. This design enables zero-shot segmentation for arbitrary text queries while capturing both semantic richness and geometric priors. Extensive experiments on large-scale urban benchmarks, including SensatUrban and SUM, show that OpenUrban3D achieves significant improvements in both segmentation accuracy and cross-scene generalization over existing methods, demonstrating its potential as a flexible and scalable solution for 3D urban scene understanding.