1.2NCSep 22, 2024
Diagnosis and Pathogenic Analysis of Autism Spectrum Disorder Using Fused Brain Connection GraphLu Wei, Yi Huang, Guosheng Yin et al.
We propose a model for diagnosing Autism spectrum disorder (ASD) using multimodal magnetic resonance imaging (MRI) data. Our approach integrates brain connectivity data from diffusion tensor imaging (DTI) and functional MRI (fMRI), employing graph neural networks (GNNs) for fused graph classification. To improve diagnostic accuracy, we introduce a loss function that maximizes inter-class and minimizes intra-class margins. We also analyze network node centrality, calculating degree, subgraph, and eigenvector centralities on a bimodal fused brain graph to identify pathological regions linked to ASD. Two non-parametric tests assess the statistical significance of these centralities between ASD patients and healthy controls. Our results reveal consistency between the tests, yet the identified regions differ significantly across centralities, suggesting distinct physiological interpretations. These findings enhance our understanding of ASD's neurobiological basis and offer new directions for clinical diagnosis.
17.6CLMar 14, 2025
Palette of Language Models: A Solver for Controlled Text GenerationZhe Yang, Yi Huang, Yaqin Chen et al.
Recent advancements in large language models have revolutionized text generation with their remarkable capabilities. These models can produce controlled texts that closely adhere to specific requirements when prompted appropriately. However, designing an optimal prompt to control multiple attributes simultaneously can be challenging. A common approach is to linearly combine single-attribute models, but this strategy often overlooks attribute overlaps and can lead to conflicts. Therefore, we propose a novel combination strategy inspired by the Law of Total Probability and Conditional Mutual Information Minimization on generative language models. This method has been adapted for single-attribute control scenario and is termed the Palette of Language Models due to its theoretical linkage between attribute strength and generation style, akin to blending colors on an artist's palette. Moreover, positive correlation and attribute enhancement are advanced as theoretical properties to guide a rational combination strategy design. We conduct experiments on both single control and multiple control settings, and achieve surpassing results.