Baojie Li

Md Mahfuzur Rahman Siddiquee, Jay Shah, Teresa Wu et al.

Harnessing the power of deep neural networks in the medical imaging domain is challenging due to the difficulties in acquiring large annotated datasets, especially for rare diseases, which involve high costs, time, and effort for annotation. Unsupervised disease detection methods, such as anomaly detection, can significantly reduce human effort in these scenarios. While anomaly detection typically focuses on learning from images of healthy subjects only, real-world situations often present unannotated datasets with a mixture of healthy and diseased subjects. Recent studies have demonstrated that utilizing such unannotated images can improve unsupervised disease and anomaly detection. However, these methods do not utilize knowledge specific to registered neuroimages, resulting in a subpar performance in neurologic disease detection. To address this limitation, we propose Brainomaly, a GAN-based image-to-image translation method specifically designed for neurologic disease detection. Brainomaly not only offers tailored image-to-image translation suitable for neuroimages but also leverages unannotated mixed images to achieve superior neurologic disease detection. Additionally, we address the issue of model selection for inference without annotated samples by proposing a pseudo-AUC metric, further enhancing Brainomaly's detection performance. Extensive experiments and ablation studies demonstrate that Brainomaly outperforms existing state-of-the-art unsupervised disease and anomaly detection methods by significant margins in Alzheimer's disease detection using a publicly available dataset and headache detection using an institutional dataset. The code is available from https://github.com/mahfuzmohammad/Brainomaly.

Pak Lun Kevin Ding, Zhiqiang Li, Yuxiang Zhou et al.

Typical Magnetic Resonance Imaging (MRI) scan may take 20 to 60 minutes. Reducing MRI scan time is beneficial for both patient experience and cost considerations. Accelerated MRI scan may be achieved by acquiring less amount of k-space data (down-sampling in the k-space). However, this leads to lower resolution and aliasing artifacts for the reconstructed images. There are many existing approaches for attempting to reconstruct high-quality images from down-sampled k-space data, with varying complexity and performance. In recent years, deep-learning approaches have been proposed for this task, and promising results have been reported. Still, the problem remains challenging especially because of the high fidelity requirement in most medical applications employing reconstructed MRI images. In this work, we propose a deep-learning approach, aiming at reconstructing high-quality images from accelerated MRI acquisition. Specifically, we use Convolutional Neural Network (CNN) to learn the differences between the aliased images and the original images, employing a U-Net-like architecture. Further, a micro-architecture termed Residual Dense Block (RDB) is introduced for learning a better feature representation than the plain U-Net. Considering the peculiarity of the down-sampled k-space data, we introduce a new term to the loss function in learning, which effectively employs the given k-space data during training to provide additional regularization on the update of the network weights. To evaluate the proposed approach, we compare it with other state-of-the-art methods. In both visual inspection and evaluation using standard metrics, the proposed approach is able to deliver improved performance, demonstrating its potential for providing an effective solution.

Vijetha Gattupalli, Yaoxin Zhuo, Baoxin Li

Many approaches to semantic image hashing have been formulated as supervised learning problems that utilize images and label information to learn the binary hash codes. However, large-scale labeled image data is expensive to obtain, thus imposing a restriction on the usage of such algorithms. On the other hand, unlabelled image data is abundant due to the existence of many Web image repositories. Such Web images may often come with images tags that contain useful information, although raw tags, in general, do not readily lead to semantic labels. Motivated by this scenario, we formulate the problem of semantic image hashing as a weakly-supervised learning problem. We utilize the information contained in the user-generated tags associated with the images to learn the hash codes. More specifically, we extract the word2vec semantic embeddings of the tags and use the information contained in them for constraining the learning. Accordingly, we name our model Weakly Supervised Deep Hashing using Tag Embeddings (WDHT). WDHT is tested for the task of semantic image retrieval and is compared against several state-of-art models. Results show that our approach sets a new state-of-art in the area of weekly supervised image hashing.