Saurabh J. Shigwan

VSS Tejaswi Abburi, Saurabh J. Shigwan, Nitin Kumar

In biomedical and neurodegenerative disorders, accurate and early disease identification remains challenging due to the scarcity of labeled data and the complexity of imaging patterns. To address these challenges, we introduce ARMA-C3, a unified unsupervised and semi-supervised graph learning framework for node classification based on contrastive learning and graph-cut regularization to learn structurally meaningful and discriminative representations. By modeling samples or images as graph nodes and exploiting inter-sample relationships, the proposed framework captures subject-level dependencies that conventional machine learning methods typically overlook. We conduct extensive binary classification experiments across five clinically relevant datasets: the Alzheimer's Disease Neuroimaging Initiative (ADNI), the Neuroimaging in Frontotemporal Dementia (NIFD) dataset, and three medical imaging benchmarks (BreastMNIST, PneumoniaMNIST, and a liver ultrasound dataset). Experimental results demonstrate that ARMA-C3 achieves competitive and frequently superior performance compared to classical clustering techniques, state-of-the-art machine learning models, and existing graph-based deep learning approaches across multiple evaluation settings, particularly under limited supervision and severe class imbalance. The proposed framework further demonstrates robust representation learning and strong cross-modal generalization across diverse biomedical imaging modalities.

K S Nithurshen, Saurabh J. Shigwan

Automated segmentation of the vertebral column in Computed Tomography (CT) scans is a prerequisite for pathological assessment and surgical planning. However, state-of-the-art methods, particularly those based on Transformers or large-scale ensembles, demand substantial GPU resources, creating a barrier for clinical adoption in resource-constrained environments or on edge devices. To address this, we introduce SpineContextResUNet, a computationally efficient 3D Residual U-Net designed for rapid spinal localization. Our architecture integrates a lightweight Context Block that employs parallel multi-dilated convolutions to capture long-range anatomical dependencies without the high latency of Recurrent Neural Networks (RNNs) or the memory overhead of Self-Attention mechanisms. Extensive validation on two public benchmarks, VerSe2020 and CTSpine1K, demonstrates that our model achieves a Dice score of 88.17% and 88.13% respectively. To evaluate performance under strict hardware constraints, we compared our model against a bottlenecked SwinUNETR scaled to match our ~1.7M hardware footprint. While the constrained Transformer suffers severe performance degradation due to a lack of spatial inductive biases in a limited-data regime, our CNN-based approach successfully maintains high accuracy. Crucially, heavy baselines like TotalSegmentator fail due to memory exhaustion on commodity hardware (Intel Core i5, 8GB RAM), our model performs robust inference, making it a viable solution for point-of-care diagnostics and deployment on edge platforms like the Nvidia Jetson Orin Nano.

A. Mudit Adityaja, Saurabh J. Shigwan, Nitin Kumar

The data-intensive nature of supervised classification drives the interest of the researchers towards unsupervised approaches, especially for problems such as medical image segmentation, where labeled data is scarce. Building on the recent advancements of Vision transformers (ViT) in computer vision, we propose an unsupervised segmentation framework using a pre-trained Dino-ViT. In the proposed method, we leverage the inherent graph structure within the image to realize a significant performance gain for segmentation in medical images. For this, we introduce a modularity-based loss function coupled with a Graph Attention Network (GAT) to effectively capture the inherent graph topology within the image. Our method achieves state-of-the-art performance, even significantly surpassing or matching that of existing (semi)supervised technique such as MedSAM which is a Segment Anything Model in medical images. We demonstrate this using two challenging medical image datasets ISIC-2018 and CVC-ColonDB. This work underscores the potential of unsupervised approaches in advancing medical image analysis in scenarios where labeled data is scarce. The github repository of the code is available on [https://github.com/mudit-adityaja/UnSegMedGAT].

Kovvuri Sai Gopal Reddy, Bodduluri Saran, A. Mudit Adityaja et al.

Image segmentation, the process of partitioning an image into meaningful regions, plays a pivotal role in computer vision and medical imaging applications. Unsupervised segmentation, particularly in the absence of labeled data, remains a challenging task due to the inter-class similarity and variations in intensity and resolution. In this study, we extract high-level features of the input image using pretrained vision transformer. Subsequently, the proposed method leverages the underlying graph structures of the images, seeking to discover and delineate meaningful boundaries using graph neural networks and modularity based optimization criteria without relying on pre-labeled training data. Experimental results on benchmark datasets demonstrate the effectiveness and versatility of the proposed approach, showcasing competitive performance compared to the state-of-the-art unsupervised segmentation methods. This research contributes to the broader field of unsupervised medical imaging and computer vision by presenting an innovative methodology for image segmentation that aligns with real-world challenges. The proposed method holds promise for diverse applications, including medical imaging, remote sensing, and object recognition, where labeled data may be scarce or unavailable. The github repository of the code is available on [https://github.com/ksgr5566/unseggnet]

Vishal, Arnav Aditya, Nitin Kumar et al.

Medical imaging datasets are often characterized by extreme class imbalances, where rare pathologies are significantly underrepresented compared to common conditions. This imbalance poses a dual challenge for Open-Set Recognition (OSR): models must maintain high classification accuracy on known classes while reliably rejecting unknown samples unseen during training in the clinical settings. While recently proposed Deep Simplex Classifier (DSC)~\cite{cevikalp2024reaching} and UnCertainty-aware Deep Simplex Classifier (UCDSC)~\cite{Aditya_2026_WACV} successfully leverage Neural Collapse to ensure maximal inter-class separation, they rely on a uniform margin that does not account for the varying densities of medical classes. In this paper, we propose DMDSC an enhanced framework featuring a dynamic margin approach. Our approach automatically adapts class-specific margins based on label frequency, enforcing a higher penalty and tighter feature clustering for rare pathologies to counteract the effects of data imbalance. Extensive experiments conducted on diverse medical benchmarks on BloodMNIST\cite{medmnistv2}, OCTMNIST\cite{medmnistv2}, DermaMNIST\cite{medmnistv2}, and BreaKHis~\cite{spanhol2015dataset} datasets, demonstrate that our framework outperforms state-of-the-art methods.