Ahmad Mustafa

Yash-yee Logan, Ryan Benkert, Ahmad Mustafa et al.

This paper considers making active learning more sensible from a medical perspective. In practice, a disease manifests itself in different forms across patient cohorts. Existing frameworks have primarily used mathematical constructs to engineer uncertainty or diversity-based methods for selecting the most informative samples. However, such algorithms do not present themselves naturally as usable by the medical community and healthcare providers. Thus, their deployment in clinical settings is very limited, if any. For this purpose, we propose a framework that incorporates clinical insights into the sample selection process of active learning that can be incorporated with existing algorithms. Our medically interpretable active learning framework captures diverse disease manifestations from patients to improve generalization performance of OCT classification. After comprehensive experiments, we report that incorporating patient insights within the active learning framework yields performance that matches or surpasses five commonly used paradigms on two architectures with a dataset having imbalanced patient distributions. Also, the framework integrates within existing medical practices and thus can be used by healthcare providers.

Ahmad Mustafa, Ghassan AlRegib

Deep learning can extract rich data representations if provided sufficient quantities of labeled training data. For many tasks however, annotating data has significant costs in terms of time and money, owing to the high standards of subject matter expertise required, for example in medical and geophysical image interpretation tasks. Active Learning can identify the most informative training examples for the interpreter to train, leading to higher efficiency. We propose an Active learning method based on jointly learning representations for supervised and unsupervised tasks. The learned manifold structure is later utilized to identify informative training samples most dissimilar from the learned manifold from the error profiles on the unsupervised task. We verify the efficiency of the proposed method on a seismic facies segmentation dataset from the Netherlands F3 block survey, significantly outperforming contemporary methods to achieve the highest mean Intersection-Over-Union value of 0.773.

Ahmad Mustafa, Ghassan AlRegib

Hydrocarbon prospect risking is a critical application in geophysics predicting well outcomes from a variety of data including geological, geophysical, and other information modalities. Traditional routines require interpreters to go through a long process to arrive at the probability of success of specific outcomes. AI has the capability to automate the process but its adoption has been limited thus far owing to a lack of transparency in the way complicated, black box models generate decisions. We demonstrate how LIME -- a model-agnostic explanation technique -- can be used to inject trust in model decisions by uncovering the model's reasoning process for individual predictions. It generates these explanations by fitting interpretable models in the local neighborhood of specific datapoints being queried. On a dataset of well outcomes and corresponding geophysical attribute data, we show how LIME can induce trust in model's decisions by revealing the decision-making process to be aligned to domain knowledge. Further, it has the potential to debug mispredictions made due to anomalous patterns in the data or faulty training datasets.

Ahmad Mustafa, Reza Rastegar, Ghassan AlRegib

Prostate gland segmentation from T2-weighted MRI is a critical yet challenging task in clinical prostate cancer assessment. While deep learning-based methods have significantly advanced automated segmentation, most conventional approaches-particularly 2D convolutional neural networks (CNNs)-fail to leverage inter-slice anatomical continuity, limiting their accuracy and robustness. Fully 3D models offer improved spatial coherence but require large amounts of annotated data, which is often impractical in clinical settings. To address these limitations, we propose a hybrid architecture that models MRI sequences as spatiotemporal data. Our method uses a deep, pretrained DeepLabV3 backbone to extract high-level semantic features from each MRI slice and a recurrent convolutional head, built with ConvLSTM layers, to integrate information across slices while preserving spatial structure. This combination enables context-aware segmentation with improved consistency, particularly in data-limited and noisy imaging conditions. We evaluate our method on the PROMISE12 benchmark under both clean and contrast-degraded test settings. Compared to state-of-the-art 2D and 3D segmentation models, our approach demonstrates superior performance in terms of precision, recall, Intersection over Union (IoU), and Dice Similarity Coefficient (DSC), highlighting its potential for robust clinical deployment.

Ahmad Mustafa, Motaz Alfarraj, Ghassan AlRegib

Seismic inversion refers to the process of estimating reservoir rock properties from seismic reflection data. Conventional and machine learning-based inversion workflows usually work in a trace-by-trace fashion on seismic data, utilizing little to no information from the spatial structure of seismic images. We propose a deep learning-based seismic inversion workflow that models each seismic trace not only temporally but also spatially. This utilizes information-relatedness in seismic traces in depth and spatial directions to make efficient rock property estimations. We empirically compare our proposed workflow with some other sequence modeling-based neural networks that model seismic data only temporally. Our results on the SEAM dataset demonstrate that, compared to the other architectures used in the study, the proposed workflow is able to achieve the best performance, with an average $r^{2}$ coefficient of 79.77\%.