Lei Cheng

Lei Cheng, Mahdi Saleh, Qing Cheng et al.

Despite the advancements in 3D full-shape generation, accurately modeling complex geometries and semantics of shape parts remains a significant challenge, particularly for shapes with varying numbers of parts. Current methods struggle to effectively integrate the contextual and structural information of 3D shapes into their generative processes. We address these limitations with PRISM, a novel compositional approach for 3D shape generation that integrates categorical diffusion models with Statistical Shape Models (SSM) and Gaussian Mixture Models (GMM). Our method employs compositional SSMs to capture part-level geometric variations and uses GMM to represent part semantics in a continuous space. This integration enables both high fidelity and diversity in generated shapes while preserving structural coherence. Through extensive experiments on shape generation and manipulation tasks, we demonstrate that our approach significantly outperforms previous methods in both quality and controllability of part-level operations. Our code will be made publicly available.

Chenglin Li, Yuanzhen Xie, Chenyun Yu et al.

Inductive representation learning on temporal heterogeneous graphs is crucial for scalable deep learning on heterogeneous information networks (HINs) which are time-varying, such as citation networks. However, most existing approaches are not inductive and thus cannot handle new nodes or edges. Moreover, previous temporal graph embedding methods are often trained with the temporal link prediction task to simulate the link formation process of temporal graphs, while ignoring the evolution of high-order topological structures on temporal graphs. To fill these gaps, we propose a Continuous-Time Representation Learning (CTRL) model on temporal HINs. To preserve heterogeneous node features and temporal structures, CTRL integrates three parts in a single layer, they are 1) a \emph{heterogeneous attention} unit that measures the semantic correlation between nodes, 2) a \emph{edge-based Hawkes process} to capture temporal influence between heterogeneous nodes, and 3) \emph{dynamic centrality} that indicates the dynamic importance of a node. We train the CTRL model with a future event (a subgraph) prediction task to capture the evolution of the high-order network structure. Extensive experiments have been conducted on three benchmark datasets. The results demonstrate that our model significantly boosts performance and outperforms various state-of-the-art approaches. Ablation studies are conducted to demonstrate the effectiveness of the model design.

Liye Mei, Yalan Yu, Yueyun Weng et al.

Chromosome karyotype analysis is of great clinical importance in the diagnosis and treatment of diseases, especially for genetic diseases. Since manual analysis is highly time and effort consuming, computer-assisted automatic chromosome karyotype analysis based on images is routinely used to improve the efficiency and accuracy of the analysis. Due to the strip shape of the chromosomes, they easily get overlapped with each other when imaged, significantly affecting the accuracy of the analysis afterward. Conventional overlapping chromosome segmentation methods are usually based on manually tagged features, hence, the performance of which is easily affected by the quality, such as resolution and brightness, of the images. To address the problem, in this paper, we present an adversarial multiscale feature learning framework to improve the accuracy and adaptability of overlapping chromosome segmentation. Specifically, we first adopt the nested U-shape network with dense skip connections as the generator to explore the optimal representation of the chromosome images by exploiting multiscale features. Then we use the conditional generative adversarial network (cGAN) to generate images similar to the original ones, the training stability of which is enhanced by applying the least-square GAN objective. Finally, we employ Lovasz-Softmax to help the model converge in a continuous optimization setting. Comparing with the established algorithms, the performance of our framework is proven superior by using public datasets in eight evaluation criteria, showing its great potential in overlapping chromosome segmentation

Ezra Webb, Cheng Lei, Chun-Jung Huang et al.

In this paper, we present contemporary techniques for visualising the feature space of a deep learning image classification neural network. These techniques are viewed in the context of a feed-forward network trained to classify low resolution fluorescence images of white blood cells captured using optofluidic imaging. The model has two output classes corresponding to two different cell types, which are often difficult to distinguish by eye. This paper has two major sections. The first looks to develop the information space presented by dimension reduction techniques, such as t-SNE, used to embed high-dimensional pre-softmax layer activations into a two-dimensional plane. The second section looks at feature visualisation by optimisation to generate feature images representing the learned features of the network. Using and developing these techniques we visualise class separation and structures within the dataset at various depths using clustering algorithms and feature images; track the development of feature complexity as we ascend the network; and begin to extract the features the network has learnt by modulating single-channel feature images with up-scaled neuron activation maps to distinguish their most salient parts.