Xi Wu

Zhenghao Feng, Lu Wen, Peng Wang et al.

Currently, deep learning (DL) has achieved the automatic prediction of dose distribution in radiotherapy planning, enhancing its efficiency and quality. However, existing methods suffer from the over-smoothing problem for their commonly used L_1 or L_2 loss with posterior average calculations. To alleviate this limitation, we innovatively introduce a diffusion-based dose prediction (DiffDP) model for predicting the radiotherapy dose distribution of cancer patients. Specifically, the DiffDP model contains a forward process and a reverse process. In the forward process, DiffDP gradually transforms dose distribution maps into Gaussian noise by adding small noise and trains a noise predictor to predict the noise added in each timestep. In the reverse process, it removes the noise from the original Gaussian noise in multiple steps with the well-trained noise predictor and finally outputs the predicted dose distribution map. To ensure the accuracy of the prediction, we further design a structure encoder to extract anatomical information from patient anatomy images and enable the noise predictor to be aware of the dose constraints within several essential organs, i.e., the planning target volume and organs at risk. Extensive experiments on an in-house dataset with 130 rectum cancer patients demonstrate the s

Yuxiang Yang, Xinyi Zeng, Pinxian Zeng et al.

Deep learning has revolutionized the early detection of breast cancer, resulting in a significant decrease in mortality rates. However, difficulties in obtaining annotations and huge variations in distribution between training sets and real scenes have limited their clinical applications. To address these limitations, unsupervised domain adaptation (UDA) methods have been used to transfer knowledge from one labeled source domain to the unlabeled target domain, yet these approaches suffer from severe domain shift issues and often ignore the potential benefits of leveraging multiple relevant sources in practical applications. To address these limitations, in this work, we construct a Three-Branch Mixed extractor and propose a Bi-level Multi-source unsupervised domain adaptation method called BTMuda for breast cancer diagnosis. Our method addresses the problems of domain shift by dividing domain shift issues into two levels: intra-domain and inter-domain. To reduce the intra-domain shift, we jointly train a CNN and a Transformer as two paths of a domain mixed feature extractor to obtain robust representations rich in both low-level local and high-level global information. As for the inter-domain shift, we redesign the Transformer delicately to a three-branch architecture with cross-attention and distillation, which learns domain-invariant representations from multiple domains. Besides, we introduce two alignment modules - one for feature alignment and one for classifier alignment - to improve the alignment process. Extensive experiments conducted on three public mammographic datasets demonstrate that our BTMuda outperforms state-of-the-art methods.

Peng Huang, Shu Hu, Bo Peng et al.

MedSAM, a medical foundation model derived from the SAM architecture, has demonstrated notable success across diverse medical domains. However, its clinical application faces two major challenges: the dependency on labor-intensive manual prompt generation, which imposes a significant burden on clinicians, and the absence of semantic labeling in the generated segmentation masks for organs or lesions, limiting its practicality for non-expert users. To address these limitations, we propose AutoMedSAM, an end-to-end framework derived from SAM, designed to enhance usability and segmentation performance. AutoMedSAM retains MedSAM's image encoder and mask decoder structure while introducing a novel diffusion-based class prompt encoder. The diffusion-based encoder employs a dual-decoder structure to collaboratively generate prompt embeddings guided by sparse and dense prompt definitions. These embeddings enhance the model's ability to understand and process clinical imagery autonomously. With this encoder, AutoMedSAM leverages class prompts to embed semantic information into the model's predictions, transforming MedSAM's semi-automated pipeline into a fully automated workflow. Furthermore, AutoMedSAM employs an uncertainty-aware joint optimization strategy during training to effectively inherit MedSAM's pre-trained knowledge while improving generalization by integrating multiple loss functions. Experimental results across diverse datasets demonstrate that AutoMedSAM achieves superior performance while broadening its applicability to both clinical settings and non-expert users. Code is available at https://github.com/HP-ML/AutoPromptMedSAM.git.

Yanfei Xiang, Yuan Gao, Hao Wu et al.

Accurate and efficient global ocean state estimation remains a grand challenge for Earth system science, hindered by the dual bottlenecks of computational scalability and degraded data fidelity in traditional data assimilation (DA) and deep learning (DL) approaches. Here we present an AI-driven Data Assimilation Framework for Ocean (ADAF-Ocean) that directly assimilates multi-source and multi-scale observations, ranging from sparse in-situ measurements to 4 km satellite swaths, without any interpolation or data thinning. Inspired by Neural Processes, ADAF-Ocean learns a continuous mapping from heterogeneous inputs to ocean states, preserving native data fidelity. Through AI-driven super-resolution, it reconstructs 0.25$^\circ$ mesoscale dynamics from coarse 1$^\circ$ fields, which ensures both efficiency and scalability, with just 3.7\% more parameters than the 1$^\circ$ configuration. When coupled with a DL forecasting system, ADAF-Ocean extends global forecast skill by up to 20 days compared to baselines without assimilation. This framework establishes a computationally viable and scientifically rigorous pathway toward real-time, high-resolution Earth system monitoring.

Jing Hu, Chengming Feng, Shu Hu et al.

Arbitrary style transfer aims to apply the style of any given artistic image to another content image. Still, existing deep learning-based methods often require significant computational costs to generate diverse stylized results. Motivated by this, we propose a novel reinforcement learning-based framework for arbitrary style transfer RLMiniStyler. This framework leverages a unified reinforcement learning policy to iteratively guide the style transfer process by exploring and exploiting stylization feedback, generating smooth sequences of stylized results while achieving model lightweight. Furthermore, we introduce an uncertainty-aware multi-task learning strategy that automatically adjusts loss weights to adapt to the content and style balance requirements at different training stages, thereby accelerating model convergence. Through a series of experiments across image various resolutions, we have validated the advantages of RLMiniStyler over other state-of-the-art methods in generating high-quality, diverse artistic image sequences at a lower cost. Codes are available at https://github.com/fengxiaoming520/RLMiniStyler.

Kaiqun Wu, Xiaoling Jiang, Rui Yu et al.

Image compression has been applied in the fields of image storage and video broadcasting. However, it's formidably tough to distinguish the subtle quality differences between those distorted images generated by different algorithms. In this paper, we propose a new image quality assessment framework to decide which image is better in an image group. To capture the subtle differences, a fine-grained network is adopted to acquire multi-scale features. Subsequently, we design a cross subtract block for separating and gathering the information within positive and negative image pairs. Enabling image comparison in feature space. After that, a progressive feature fusion block is designed, which fuses multi-scale features in a novel progressive way. Hierarchical spatial 2D features can thus be processed gradually. Experimental results show that compared with the current mainstream image quality assessment methods, the proposed network can achieve more accurate image quality assessment and ranks second in the benchmark of CLIC in the image perceptual model track.

Yuang Shi, Chen Zu, Mei Hong et al.

With the increasing amounts of high-dimensional heterogeneous data to be processed, multi-modality feature selection has become an important research direction in medical image analysis. Traditional methods usually depict the data structure using fixed and predefined similarity matrix for each modality separately, without considering the potential relationship structure across different modalities. In this paper, we propose a novel multi-modality feature selection method, which performs feature selection and local similarity learning simultaniously. Specially, a similarity matrix is learned by jointly considering different imaging modalities. And at the same time, feature selection is conducted by imposing sparse l_{2, 1} norm constraint. The effectiveness of our proposed joint learning method can be well demonstrated by the experimental results on Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset, which outperforms existing the state-of-the-art multi-modality approaches.