Yanlin Chen

Zhishe Wang, Wenyu Shao, Yanlin Chen et al.

The existing generative adversarial fusion methods generally concatenate source images and extract local features through convolution operation, without considering their global characteristics, which tends to produce an unbalanced result and is biased towards the infrared image or visible image. Toward this end, we propose a novel end-to-end mode based on generative adversarial training to achieve better fusion balance, termed as \textit{interactive compensatory attention fusion network} (ICAFusion). In particular, in the generator, we construct a multi-level encoder-decoder network with a triple path, and adopt infrared and visible paths to provide additional intensity and gradient information. Moreover, we develop interactive and compensatory attention modules to communicate their pathwise information, and model their long-range dependencies to generate attention maps, which can more focus on infrared target perception and visible detail characterization, and further increase the representation power for feature extraction and feature reconstruction. In addition, dual discriminators are designed to identify the similar distribution between fused result and source images, and the generator is optimized to produce a more balanced result. Extensive experiments illustrate that our ICAFusion obtains superior fusion performance and better generalization ability, which precedes other advanced methods in the subjective visual description and objective metric evaluation. Our codes will be public at \url{https://github.com/Zhishe-Wang/ICAFusion}

Junxuan Yu, Rusi Chen, Yongsong Zhou et al.

Echocardiography video is a primary modality for diagnosing heart diseases, but the limited data poses challenges for both clinical teaching and machine learning training. Recently, video generative models have emerged as a promising strategy to alleviate this issue. However, previous methods often relied on holistic conditions during generation, hindering the flexible movement control over specific cardiac structures. In this context, we propose an explainable and controllable method for echocardiography video generation, taking an initial frame and a motion curve as guidance. Our contributions are three-fold. First, we extract motion information from each heart substructure to construct motion curves, enabling the diffusion model to synthesize customized echocardiography videos by modifying these curves. Second, we propose the structure-to-motion alignment module, which can map semantic features onto motion curves across cardiac structures. Third, The position-aware attention mechanism is designed to enhance video consistency utilizing Gaussian masks with structural position information. Extensive experiments on three echocardiography datasets show that our method outperforms others regarding fidelity and consistency. The full code will be released at https://github.com/mlmi-2024-72/ECM.

Han Zhou, Dong Ni, Ao Chang et al.

Ultrasound (US) imaging is indispensable in clinical practice. To diagnose certain diseases, sonographers must observe corresponding dynamic anatomic structures to gather comprehensive information. However, the limited availability of specific US video cases causes teaching difficulties in identifying corresponding diseases, which potentially impacts the detection rate of such cases. The synthesis of US videos may represent a promising solution to this issue. Nevertheless, it is challenging to accurately animate the intricate motion of dynamic anatomic structures while preserving image fidelity. To address this, we present a novel online feature-decoupling framework called OnUVS for high-fidelity US video synthesis. Our highlights can be summarized by four aspects. First, we introduced anatomic information into keypoint learning through a weakly-supervised training strategy, resulting in improved preservation of anatomical integrity and motion while minimizing the labeling burden. Second, to better preserve the integrity and textural information of US images, we implemented a dual-decoder that decouples the content and textural features in the generator. Third, we adopted a multiple-feature discriminator to extract a comprehensive range of visual cues, thereby enhancing the sharpness and fine details of the generated videos. Fourth, we constrained the motion trajectories of keypoints during online learning to enhance the fluidity of generated videos. Our validation and user studies on in-house echocardiographic and pelvic floor US videos showed that OnUVS synthesizes US videos with high fidelity.

Yanlin Chen, Kehua Chen, Yinhai Wang

Traffic state estimation (TSE) becomes challenging when probe-vehicle penetration is low and observations are spatially sparse. Pure data-driven methods lack physical explanations and have poor generalization when observed data is sparse. In contrast, physical models have difficulty integrating uncertainties and capturing the real complexity of traffic. To bridge this gap, recent studies have explored combining them by embedding physical structure into Gaussian process. These approaches typically introduce the governing equations as soft constraints through pseudo-observations, enabling the integration of model structure within a variational framework. However, these methods rely heavily on penalty tuning and lack principled uncertainty calibration, which makes them sensitive to model mis-specification. In this work, we address these limitations by presenting a novel Physics-Embedded Gaussian Process (PEGP), designed to integrate domain knowledge with data-driven methods in traffic state estimation. Specifically, we design two multi-output kernels informed by classic traffic flow models, constructed via the explicit application of the linearized differential operator. Experiments on HighD, NGSIM show consistent improvements over non-physics baselines. PEGP-ARZ proves more reliable under sparse observation, while PEGP-LWR achieves lower errors with denser observation. Ablation study further reveals that PEGP-ARZ residuals align closely with physics and yield calibrated, interpretable uncertainty, whereas PEGP-LWR residuals are more orthogonal and produce nearly constant variance fields. This PEGP framework combines physical priors, uncertainty quantification, which can provide reliable support for TSE.

Jian Wang, Xin Yang, Xiaohong Jia et al.

Thyroid nodule classification and segmentation in ultrasound images are crucial for computer-aided diagnosis; however, they face limitations owing to insufficient labeled data. In this study, we proposed a multi-view contrastive self-supervised method to improve thyroid nodule classification and segmentation performance with limited manual labels. Our method aligns the transverse and longitudinal views of the same nodule, thereby enabling the model to focus more on the nodule area. We designed an adaptive loss function that eliminates the limitations of the paired data. Additionally, we adopted a two-stage pre-training to exploit the pre-training on ImageNet and thyroid ultrasound images. Extensive experiments were conducted on a large-scale dataset collected from multiple centers. The results showed that the proposed method significantly improves nodule classification and segmentation performance with limited manual labels and outperforms state-of-the-art self-supervised methods. The two-stage pre-training also significantly exceeded ImageNet pre-training.

Ruiqing Ding, Yu Zhou, Jie Xu et al.

The utilization of computer technology to solve problems in medical scenarios has attracted considerable attention in recent years, which still has great potential and space for exploration. Among them, machine learning has been widely used in the prediction, diagnosis and even treatment of Sepsis. However, state-of-the-art methods require large amounts of labeled medical data for supervised learning. In real-world applications, the lack of labeled data will cause enormous obstacles if one hospital wants to deploy a new Sepsis detection system. Different from the supervised learning setting, we need to use known information (e.g., from another hospital with rich labeled data) to help build a model with acceptable performance, i.e., transfer learning. In this paper, we propose a semi-supervised optimal transport with self-paced ensemble framework for Sepsis early detection, called SPSSOT, to transfer knowledge from the other that has rich labeled data. In SPSSOT, we first extract the same clinical indicators from the source domain (e.g., hospital with rich labeled data) and the target domain (e.g., hospital with little labeled data), then we combine the semi-supervised domain adaptation based on optimal transport theory with self-paced under-sampling to avoid a negative transfer possibly caused by covariate shift and class imbalance. On the whole, SPSSOT is an end-to-end transfer learning method for Sepsis early detection which can automatically select suitable samples from two domains respectively according to the number of iterations and align feature space of two domains. Extensive experiments on two open clinical datasets demonstrate that comparing with other methods, our proposed SPSSOT, can significantly improve the AUC values with only 1% labeled data in the target domain in two transfer learning scenarios, MIMIC $rightarrow$ Challenge and Challenge $rightarrow$ MIMIC.

Divesh Aggarwal, Yanlin Chen, Rajendra Kumar et al.

$ \newcommand{\SVP}{\textsf{SVP}} \newcommand{\CVP}{\textsf{CVP}} \newcommand{\eps}{\varepsilon} $We show a number of reductions between the Shortest Vector Problem and the Closest Vector Problem over lattices in different $\ell_p$ norms ($\SVP_p$ and $\CVP_p$ respectively). Specifically, we present the following $2^{\eps m}$-time reductions for $1 \leq p \leq q \leq \infty$, which all increase the rank $n$ and dimension $m$ of the input lattice by at most one: $\bullet$ a reduction from $\widetilde{O}(1/\eps^{1/p})γ$-approximate $\SVP_q$ to $γ$-approximate $\SVP_p$; $\bullet$ a reduction from $\widetilde{O}(1/\eps^{1/p}) γ$-approximate $\CVP_p$ to $γ$-approximate $\CVP_q$; and $\bullet$ a reduction from $\widetilde{O}(1/\eps^{1+1/p})$-$\CVP_q$ to $(1+\eps)$-unique $\SVP_p$ (which in turn trivially reduces to $(1+\eps)$-approximate $\SVP_p$). The last reduction is interesting even in the case $p = q$. In particular, this special case subsumes much prior work adapting $2^{O(m)}$-time $\SVP_p$ algorithms to solve $O(1)$-approximate $\CVP_p$. In the (important) special case when $p = q$, $1 \leq p \leq 2$, and the $\SVP_p$ oracle is exact, we show a stronger reduction, from $O(1/\eps^{1/p})\text{-}\CVP_p$ to (exact) $\SVP_p$ in $2^{\eps m}$ time. For example, taking $\eps = \log m/m$ and $p = 2$ gives a slight improvement over Kannan's celebrated polynomial-time reduction from $\sqrt{m}\text{-}\CVP_2$ to $\SVP_2$. We also note that the last two reductions can be combined to give a reduction from approximate-$\CVP_p$ to $\SVP_q$ for any $p$ and $q$, regardless of whether $p \leq q$ or $p > q$. Our techniques combine those from the recent breakthrough work of Eisenbrand and Venzin (which showed how to adapt the current fastest known algorithm for these problems in the $\ell_2$ norm to all $\ell_p$ norms) together with sparsification-based techniques.