Shengjie Liu

Shengjie Liu, Lu Zhang, Siqin Wang

Central to Earth observation is the trade-off between spatial and temporal resolution. For temperature, this is especially critical because real-world applications require high spatiotemporal resolution data. Current technology allows for hourly temperature observations at 2 km, but only every 16 days at 100 m, a gap further exacerbated by cloud cover. Earth system models offer continuous hourly temperature data, but at a much coarser spatial resolution (9-31 km). Here, we present a physics-guided deep learning framework for temperature data reconstruction that integrates these two data sources. The proposed framework uses a convolutional neural network that incorporates the annual temperature cycle and includes a linear term to amplify the coarse Earth system model output into fine-scale temperature values observed from satellites. We evaluated this framework using data from two satellites, GOES-16 (2 km, hourly) and Landsat (100 m, every 16 days), and demonstrated effective temperature reconstruction with hold-out and in situ data across four datasets. This physics-guided deep learning framework opens new possibilities for generating high-resolution temperature data across spatial and temporal scales, under all weather conditions and globally.

Chuang Zhu, Shengjie Liu, Zekuan Yu et al.

For invasive breast cancer, immunohistochemical (IHC) techniques are often used to detect the expression level of human epidermal growth factor receptor-2 (HER2) in breast tissue to formulate a precise treatment plan. From the perspective of saving manpower, material and time costs, directly generating IHC-stained images from Hematoxylin and Eosin (H&E) stained images is a valuable research direction. Therefore, we held the breast cancer immunohistochemical image generation challenge, aiming to explore novel ideas of deep learning technology in pathological image generation and promote research in this field. The challenge provided registered H&E and IHC-stained image pairs, and participants were required to use these images to train a model that can directly generate IHC-stained images from corresponding H&E-stained images. We selected and reviewed the five highest-ranking methods based on their PSNR and SSIM metrics, while also providing overviews of the corresponding pipelines and implementations. In this paper, we further analyze the current limitations in the field of breast cancer immunohistochemical image generation and forecast the future development of this field. We hope that the released dataset and the challenge will inspire more scholars to jointly study higher-quality IHC-stained image generation.