Qian Zhao

Mingrui Geng, Yun Deng, Qian Zhao et al.

Recently, deep learning(DL) methods have been proposed for the low-dose computed tomography(LdCT) enhancement, and obtain good trade-off between computational efficiency and image quality. Most of them need large number of pre-collected ground-truth/high-dose sinograms with less noise, and train the network in a supervised end-to-end manner. This may bring major limitations on these methods because the number of such low-dose/high-dose training sinogram pairs would affect the network's capability and sometimes the ground-truth sinograms are hard to be obtained in large scale. Since large number of low-dose ones are relatively easy to obtain, it should be critical to make these sources play roles in network training in an unsupervised learning manner. To address this issue, we propose an unsupervised DL method for LdCT enhancement that incorporates unlabeled LdCT sinograms directly into the network training. The proposed method effectively considers the structure characteristics and noise distribution in the measured LdCT sinogram, and then learns the proper gradient of the LdCT sinogram in a pure unsupervised manner. Similar to the labeled ground-truth, the gradient information in an unlabeled LdCT sinogram can be used for sufficient network training. The experiments on the patient data show effectiveness of the proposed method.

Xi'ai Chen, Zhi Han, Yao Wang et al.

Because of the limitations of matrix factorization, such as losing spatial structure information, the concept of low-rank tensor factorization (LRTF) has been applied for the recovery of a low dimensional subspace from high dimensional visual data. The low-rank tensor recovery is generally achieved by minimizing the loss function between the observed data and the factorization representation. The loss function is designed in various forms under different noise distribution assumptions, like $L_1$ norm for Laplacian distribution and $L_2$ norm for Gaussian distribution. However, they often fail to tackle the real data which are corrupted by the noise with unknown distribution. In this paper, we propose a generalized weighted low-rank tensor factorization method (GWLRTF) integrated with the idea of noise modelling. This procedure treats the target data as high-order tensor directly and models the noise by a Mixture of Gaussians, which is called MoG GWLRTF. The parameters in the model are estimated under the EM framework and through a new developed algorithm of weighted low-rank tensor factorization. We provide two versions of the algorithm with different tensor factorization operations, i.e., CP factorization and Tucker factorization. Extensive experiments indicate the respective advantages of this two versions in different applications and also demonstrate the effectiveness of MoG GWLRTF compared with other competing methods.