Yang Gao

Zhuang Xiong, Yang Gao, Yin Liu et al.

The data-driven approach of supervised learning methods has limited applicability in solving dipole inversion in Quantitative Susceptibility Mapping (QSM) with varying scan parameters across different objects. To address this generalization issue in supervised QSM methods, we propose a novel training-free model-based unsupervised method called MoDIP (Model-based Deep Image Prior). MoDIP comprises a small, untrained network and a Data Fidelity Optimization (DFO) module. The network converges to an interim state, acting as an implicit prior for image regularization, while the optimization process enforces the physical model of QSM dipole inversion. Experimental results demonstrate MoDIP's excellent generalizability in solving QSM dipole inversion across different scan parameters. It exhibits robustness against pathological brain QSM, achieving over 32% accuracy improvement than supervised deep learning and traditional iterative methods. It is also 33% more computationally efficient and runs 4 times faster than conventional DIP-based approaches, enabling 3D high-resolution image reconstruction in under 4.5 minutes.

Hongye Cao, Yanming Wang, Sijia Jing et al.

With the rapid advancement of Large Language Models (LLMs), the safety of LLMs has been a critical concern requiring precise assessment. Current benchmarks primarily concentrate on single-turn dialogues or a single jailbreak attack method to assess the safety. Additionally, these benchmarks have not taken into account the LLM's capability of identifying and handling unsafe information in detail. To address these issues, we propose a fine-grained benchmark SafeDialBench for evaluating the safety of LLMs across various jailbreak attacks in multi-turn dialogues. Specifically, we design a two-tier hierarchical safety taxonomy that considers 6 safety dimensions and generates more than 4000 multi-turn dialogues in both Chinese and English under 22 dialogue scenarios. We employ 7 jailbreak attack strategies, such as reference attack and purpose reverse, to enhance the dataset quality for dialogue generation. Notably, we construct an innovative assessment framework of LLMs, measuring capabilities in detecting, and handling unsafe information and maintaining consistency when facing jailbreak attacks. Experimental results across 17 LLMs reveal that Yi-34B-Chat and GLM4-9B-Chat demonstrate superior safety performance, while Llama3.1-8B-Instruct and o3-mini exhibit safety vulnerabilities.

Zhuang Xiong, Wei Jiang, Yang Gao et al.

Quantitative Susceptibility Mapping (QSM) dipole inversion is an ill-posed inverse problem for quantifying magnetic susceptibility distributions from MRI tissue phases. While supervised deep learning methods have shown success in specific QSM tasks, their generalizability across different acquisition scenarios remains constrained. Recent developments in diffusion models have demonstrated potential for solving 2D medical imaging inverse problems. However, their application to 3D modalities, such as QSM, remains challenging due to high computational demands. In this work, we developed a 3D image patch-based diffusion model, namely QSMDiff, for robust QSM reconstruction across different scan parameters, alongside simultaneous super-resolution and image-denoising tasks. QSMDiff adopts unsupervised 3D image patch training and full-size measurement guidance during inference for controlled image generation. Evaluation on simulated and in-vivo human brains, using gradient-echo and echo-planar imaging sequences across different acquisition parameters, demonstrates superior performance. The method proposed in QSMDiff also holds promise for impacting other 3D medical imaging applications beyond QSM.

Gao Yang, Yuhang Liu, Siyu Miao et al.

Ideal or real - that is the question.In this work, we explore whether principles from game theory can be effectively applied to the evaluation of large language models (LLMs). This inquiry is motivated by the growing inadequacy of conventional evaluation practices, which often rely on fixed-format tasks with reference answers and struggle to capture the nuanced, subjective, and open-ended nature of modern LLM behavior. To address these challenges, we propose a novel alternative: automatic mutual evaluation, where LLMs assess each other's output through self-play and peer review. These peer assessments are then systematically compared with human voting behavior to evaluate their alignment with human judgment. Our framework incorporates game-theoretic voting algorithms to aggregate peer reviews, enabling a principled investigation into whether model-generated rankings reflect human preferences. Empirical results reveal both convergences and divergences between theoretical predictions and human evaluations, offering valuable insights into the promises and limitations of mutual evaluation. To the best of our knowledge, this is the first work to jointly integrate mutual evaluation, game-theoretic aggregation, and human-grounded validation for evaluating the capabilities of LLMs.

Tianyi Ding, Hongli Chen, Yang Gao et al.

Magnetic Resonance Fingerprinting (MRF) enables fast quantitative imaging by matching signal evolutions to a predefined dictionary. However, conventional dictionary matching suffers from exponential growth in computational cost and memory usage as the number of parameters increases, limiting its scalability to multi-parametric mapping. To address this, recent work has explored deep learning-based approaches as alternatives to DM. We propose GAST-Mamba, an end-to-end framework that combines a dual Mamba-based encoder with a Gate-Aware Spatial-Temporal (GAST) processor. Built on structured state-space models, our architecture efficiently captures long-range spatial dependencies with linear complexity. On 5 times accelerated simulated MRF data (200 frames), GAST-Mamba achieved a T1 PSNR of 33.12~dB, outperforming SCQ (31.69~dB). For T2 mapping, it reached a PSNR of 30.62~dB and SSIM of 0.9124. In vivo experiments further demonstrated improved anatomical detail and reduced artifacts. Ablation studies confirmed that each component contributes to performance, with the GAST module being particularly important under strong undersampling. These results demonstrate the effectiveness of GAST-Mamba for accurate and robust reconstruction from highly undersampled MRF acquisitions, offering a scalable alternative to traditional DM-based methods.

Min Li, Chen Chen, Zhuang Xiong et al.

Quantitative susceptibility mapping (QSM) is an MRI phase-based post-processing technique to extract the distribution of tissue susceptibilities, demonstrating significant potential in studying neurological diseases. However, the ill-conditioned nature of dipole inversion makes QSM reconstruction from the tissue field prone to noise and artifacts. In this work, we propose a novel deep learning-based IR2QSM method for QSM reconstruction. It is designed by iterating four times of a reverse concatenations and middle recurrent modules enhanced U-net, which could dramatically improve the efficiency of latent feature utilization. Simulated and in vivo experiments were conducted to compare IR2QSM with several traditional algorithms (MEDI and iLSQR) and state-of-the-art deep learning methods (U-net, xQSM, and LPCNN). The results indicated that IR2QSM was able to obtain QSM images with significantly increased accuracy and mitigated artifacts over other methods. Particularly, IR2QSM demonstrated on average the best NRMSE (27.59%) in simulated experiments, which is 15.48%, 7.86%, 17.24%, 9.26%, and 29.13% lower than iLSQR, MEDI, U-net, xQSM, LPCNN, respectively, and led to improved QSM results with fewer artifacts for the in vivo data.

Bhargav Pulugundla, Yang Gao, Brian King et al.

Attention-based beamformers have recently been shown to be effective for multi-channel speech recognition. However, they are less capable at capturing local information. In this work, we propose a 2D Conv-Attention module which combines convolution neural networks with attention for beamforming. We apply self- and cross-attention to explicitly model the correlations within and between the input channels. The end-to-end 2D Conv-Attention model is compared with a multi-head self-attention and superdirective-based neural beamformers. We train and evaluate on an in-house multi-channel dataset. The results show a relative improvement of 3.8% in WER by the proposed model over the baseline neural beamformer.

Shuming Jiao, Dongfang Zhang, Chonglei Zhang et al.

A digital micromirror device (DMD) is an amplitude-type spatial light modulator. However, a complex-amplitude light modulation with a DMD can be achieved using the superpixel scheme. In the superpixel scheme, we notice that multiple different DMD local block patterns may correspond to the same complex superpixel value. Based on this inherent encoding redundancy, a large amount of external data can be embedded into the DMD pattern without extra cost. Meanwhile, the original complex light field information carried by the DMD pattern is fully preserved. This proposed scheme is favorable for applications such as secure information transmission and copyright protection.

Shuming Jiao, Yang Gao, Ting Lei et al.

In many previous works, a single-pixel imaging (SPI) system is constructed as an optical image encryption system. Unauthorized users are not able to reconstruct the plaintext image from the ciphertext intensity sequence without knowing the illumination pattern key. However, little cryptanalysis about encrypted SPI has been investigated in the past. In this work, we propose a known-plaintext attack scheme and a ciphertext-only attack scheme to an encrypted SPI system for the first time. The known-plaintext attack is implemented by interchanging the roles of illumination patterns and object images in the SPI model. The ciphertext-only attack is implemented based on the statistical features of single-pixel intensity values. The two schemes can crack encrypted SPI systems and successfully recover the key containing correct illumination patterns.

Yang Gao, Shuming Jiao, Juncheng Fang et al.

A cascaded phase-only mask architecture (or an optical diffractive neural network) can be employed for different optical information processing tasks such as pattern recognition, orbital angular momentum (OAM) mode conversion, image salience detection and image encryption. However, for optical encryption and watermarking applications, such a system usually cannot process multiple pairs of input images and output images simultaneously. In our proposed scheme, multiple input images can be simultaneously fed to an optical diffractive neural network (DNN) system and each corresponding output image will be displayed in a non-overlap sub-region in the output imaging plane. Each input image undergoes a different optical transform in an independent channel within the same system. The multiple cascaded phase masks in the system can be effectively optimized by a wavefront matching algorithm. Similar to recent optical pattern recognition and mode conversion works, the orthogonality property is employed to design a multiplexed DNN.

Jun Feng, Shuming Jiao, Yang Gao et al.

Single-pixel imaging (SPI) has a major drawback that many sequential illuminations are required for capturing one single image with long acquisition time. Basis illumination patterns such as Fourier patterns and Hadamard patterns can achieve much better imaging efficiency than random patterns. But the performance is still sub-optimal since the basis patterns are fixed and non-adaptive for varying object images. This Letter proposes a novel scheme for designing and optimizing the illumination patterns adaptively from an image dictionary by extracting the common image features using principal component analysis (PCA). Simulation and experimental results reveal that our proposed scheme outperforms conventional Fourier SPI in terms of imaging efficiency.