Onur Özdemir

Onur Ozdemir, Rebecca L. Russell, Andrew A. Berlin

We introduce a new computer aided detection and diagnosis system for lung cancer screening with low-dose CT scans that produces meaningful probability assessments. Our system is based entirely on 3D convolutional neural networks and achieves state-of-the-art performance for both lung nodule detection and malignancy classification tasks on the publicly available LUNA16 and Kaggle Data Science Bowl challenges. While nodule detection systems are typically designed and optimized on their own, we find that it is important to consider the coupling between detection and diagnosis components. Exploiting this coupling allows us to develop an end-to-end system that has higher and more robust performance and eliminates the need for a nodule detection false positive reduction stage. Furthermore, we characterize model uncertainty in our deep learning systems, a first for lung CT analysis, and show that we can use this to provide well-calibrated classification probabilities for both nodule detection and patient malignancy diagnosis. These calibrated probabilities informed by model uncertainty can be used for subsequent risk-based decision making towards diagnostic interventions or disease treatments, as we demonstrate using a probability-based patient referral strategy to further improve our results.

Jacob Harer, Onur Ozdemir, Tomo Lazovich et al.

Motivated by the problem of automated repair of software vulnerabilities, we propose an adversarial learning approach that maps from one discrete source domain to another target domain without requiring paired labeled examples or source and target domains to be bijections. We demonstrate that the proposed adversarial learning approach is an effective technique for repairing software vulnerabilities, performing close to seq2seq approaches that require labeled pairs. The proposed Generative Adversarial Network approach is application-agnostic in that it can be applied to other problems similar to code repair, such as grammar correction or sentiment translation.

Onur Ozdemir, Benjamin Woodward, Andrew A. Berlin

Motivated by the problem of computer-aided detection (CAD) of pulmonary nodules, we introduce methods to propagate and fuse uncertainty information in a multi-stage Bayesian convolutional neural network (CNN) architecture. The question we seek to answer is "can we take advantage of the model uncertainty provided by one deep learning model to improve the performance of the subsequent deep learning models and ultimately of the overall performance in a multi-stage Bayesian deep learning architecture?". Our experiments show that propagating uncertainty through the pipeline enables us to improve the overall performance in terms of both final prediction accuracy and model confidence.

Onur Ozdemir, Ruoyu Li, Pramod K. Varshney

The performance of a modulation classifier is highly sensitive to channel signal-to-noise ratio (SNR). In this paper, we focus on amplitude-phase modulations and propose a modulation classification framework based on centralized data fusion using multiple radios and the hybrid maximum likelihood (ML) approach. In order to alleviate the computational complexity associated with ML estimation, we adopt the Expectation Maximization (EM) algorithm. Due to SNR diversity, the proposed multi-radio framework provides robustness to channel SNR. Numerical results show the superiority of the proposed approach with respect to single radio approaches as well as to modulation classifiers using moments based estimators.