Mohammad Eslami

Mohammad Eslami, Solale Tabarestani, Ehsan Adeli et al.

With the advent of sophisticated machine learning (ML) techniques and the promising results they yield, especially in medical applications, where they have been investigated for different tasks to enhance the decision-making process. Since visualization is such an effective tool for human comprehension, memorization, and judgment, we have presented a first-of-its-kind estimation approach we refer to as Visualized Learning for Machine Learning (VL4ML) that not only can serve to assist physicians and clinicians in making reasoned medical decisions, but it also allows to appreciate the uncertainty visualization, which could raise incertitude in making the appropriate classification or prediction. For the proof of concept, and to demonstrate the generalized nature of this visualized estimation approach, five different case studies are examined for different types of tasks including classification, regression, and longitudinal prediction. A survey analysis with more than 100 individuals is also conducted to assess users' feedback on this visualized estimation method. The experiments and the survey demonstrate the practical merits of the VL4ML that include: (1) appreciating visually clinical/medical estimations; (2) getting closer to the patients' preferences; (3) improving doctor-patient communication, and (4) visualizing the uncertainty introduced through the black box effect of the deployed ML algorithm. All the source codes are shared via a GitHub repository.

Mohammad Eslami, Dhanvinkumar Ganeshkumar, Saber Kazeminasab et al.

We present CataractSAM-2, a domain-adapted extension of Meta's Segment Anything Model 2, designed for real-time semantic segmentation of cataract ophthalmic surgery videos with high accuracy. Positioned at the intersection of computer vision and medical robotics, CataractSAM-2 enables precise intraoperative perception crucial for robotic-assisted and computer-guided surgical systems. Furthermore, to alleviate the burden of manual labeling, we introduce an interactive annotation framework that combines sparse prompts with video-based mask propagation. This tool significantly reduces annotation time and facilitates the scalable creation of high-quality ground-truth masks, accelerating dataset development for ocular anterior segment surgeries. We also demonstrate the model's strong zero-shot generalization to glaucoma trabeculectomy procedures, confirming its cross-procedural utility and potential for broader surgical applications. The trained model and annotation toolkit are released as open-source resources, establishing CataractSAM-2 as a foundation for expanding anterior ophthalmic surgical datasets and advancing real-time AI-driven solutions in medical robotics, as well as surgical video understanding.

Mohammad Hasan Ahmadilivani, Levent Aksoy, Mohammad Eslami et al.

Long Short-Term Memory (LSTM) neural networks have penetrated healthcare applications where real-time requirements and edge computing capabilities are essential. Gait analysis that detects abnormal steps to prevent patients from falling is a prominent problem for such applications. Given the extremely stringent design requirements in performance, power dissipation, and area, an Application-Specific Integrated Circuit (ASIC) enables an efficient real-time exploitation of LSTMs for gait analysis, achieving high accuracy. To the best of our knowledge, this work presents the first cross-layer co-optimized LSTM accelerator for real-time gait analysis, targeting an ASIC design. We conduct a comprehensive design space exploration from software down to layout design. We carry out a bit-width optimization at the software level with hardware-aware quantization to reduce the hardware complexity, explore various designs at the register-transfer level, and generate alternative layouts to find efficient realizations of the LSTM accelerator in terms of hardware complexity and accuracy. The physical synthesis results show that, using the 65 nm technology, the die size of the accelerator's layout optimized for the highest accuracy is 0.325 mm^2, while the alternative design optimized for hardware complexity with a slightly lower accuracy occupies 15.4% smaller area. Moreover, the designed accelerators achieve accurate gait abnormality detection 4.05x faster than the given application requirement.

Farzin Soleymani, Mohammad Eslami, Tobias Elze et al.

We propose a Deep Variational Clustering (DVC) framework for unsupervised representation learning and clustering of large-scale medical images. DVC simultaneously learns the multivariate Gaussian posterior through the probabilistic convolutional encoder and the likelihood distribution with the probabilistic convolutional decoder; and optimizes cluster labels assignment. Here, the learned multivariate Gaussian posterior captures the latent distribution of a large set of unlabeled images. Then, we perform unsupervised clustering on top of the variational latent space using a clustering loss. In this approach, the probabilistic decoder helps to prevent the distortion of data points in the latent space and to preserve the local structure of data generating distribution. The training process can be considered as a self-training process to refine the latent space and simultaneously optimizing cluster assignments iteratively. We evaluated our proposed framework on three public datasets that represented different medical imaging modalities. Our experimental results show that our proposed framework generalizes better across different datasets. It achieves compelling results on several medical imaging benchmarks. Thus, our approach offers potential advantages over conventional deep unsupervised learning in real-world applications. The source code of the method and all the experiments are available publicly at: https://github.com/csfarzin/DVC

Mohammad Eslami, Mahdi Karami, Sedigheh Eslami et al.

Sign(ed) languages use gestures, such as hand or head movements, for communication. Sign language recognition is an assistive technology for individuals with hearing disability and its goal is to improve such individuals' life quality by facilitating their social involvement. Since sign languages are vastly varied in alphabets, as known as signs, a sign recognition software should be capable of handling eight different types of sign combinations, e.g. numbers, letters, words and sentences. Due to the intrinsic complexity and diversity of symbolic gestures, recognition algorithms need a comprehensive visual dataset to learn by. In this paper, we describe the design and implementation of a Microsoft Kinect-based open source software, called SignCol, for capturing and saving the gestures used in sign languages. Our work supports a multi-language database and reports the recorded items statistics. SignCol can capture and store colored(RGB) frames, depth frames, infrared frames, body index frames, coordinate mapped color-body frames, skeleton information of each frame and camera parameters simultaneously.

Gajan Mohan Raj, Michael G. Morley, Mohammad Eslami

Diabetic retinopathy is the leading cause of vision loss in working-age adults worldwide, yet under-resourced regions lack ophthalmologists. Current state-of-the-art deep learning systems struggle at these institutions due to limited generalizability. This paper explores a novel federated learning system for diabetic retinopathy diagnosis with the EfficientNetB0 architecture to leverage fundus data from multiple institutions to improve diagnostic generalizability at under-resourced hospitals while preserving patient-privacy. The federated model achieved 93.21% accuracy in five-category classification on an unseen dataset and 91.05% on lower-quality images from a simulated under-resourced institution. The model was deployed onto two apps for quick and accurate diagnosis.

Mohammad Eslami, Tara Ghasempouri, Samuel Pagliarini

Globalization in the semiconductor industry enables fabless design houses to reduce their costs, save time, and make use of newer technologies. However, the offshoring of Integrated Circuit (IC) fabrication has negative sides, including threats such as Hardware Trojans (HTs) - a type of malicious logic that is not trivial to detect. One aspect of IC design that is not affected by globalization is the need for thorough verification. Verification engineers devise complex assets to make sure designs are bug-free, including assertions. This knowledge is typically not reused once verification is over. The premise of this paper is that verification assets that already exist can be turned into effective security checkers for HT detection. For this purpose, we show how assertions can be used as online monitors. To this end, we propose a security metric and an assertion selection flow that leverages Cadence JasperGold Security Path Verification (SPV). The experimental results show that our approach scales for industry-size circuits by analyzing more than 100 assertions for different Intellectual Properties (IPs) of the OpenTitan System-on-Chip (SoC). Moreover, our detection solution is pragmatic since it does not rely on the HT activation mechanism.

Mohammad Eslami, Solale Tabarestani, Malek Adjouadi

Neuroimaging is essential in brain studies for the diagnosis and identification of disease, structure, and function of the brain in its healthy and disease states. Literature shows that there are advantages of multitasking with some deep learning (DL) schemes in challenging neuroimaging applications. This study examines the feasibility of using multitasking in three different applications, including tissue segmentation, cross-modality conversion, and bias-field correction. These applications reflect five different scenarios in which multitasking is explored and 280 training and testing sessions conducted for empirical evaluations. Two well-known networks, U-Net as a well-known convolutional neural network architecture, and a closed architecture based on the conditional generative adversarial network are implemented. Different metrics such as the normalized cross-correlation coefficient and Dice scores are used for comparison of methods and results of the different experiments. Statistical analysis is also provided by paired t-test. The present study explores the pros and cons of these methods and their practical impacts on multitasking in different implementation scenarios. This investigation shows that bias correction and cross-modality conversion applications are significantly easier than the segmentation application, and having multitasking with segmentation is not reasonable if one of them is identified as the main target application. However, when the main application is the segmentation of tissues, multitasking with cross-modality conversion is beneficial, especially for the U-net architecture.

Mohammad Eslami, Christiane Neuschaefer-Rube, Antoine Serrurier

The various speech sounds of a language are obtained by varying the shape and position of the articulators surrounding the vocal tract. Analyzing their variations is crucial for understanding speech production, diagnosing speech disorders and planning therapy. Identifying key anatomical landmarks of these structures on medical images is a pre-requisite for any quantitative analysis and the rising amount of data generated in the field calls for an automatic solution. The challenge lies in the high inter- and intra-speaker variability, the mutual interaction between the articulators and the moderate quality of the images. This study addresses this issue for the first time and tackles it by means by means of Deep Learning. It proposes a dedicated network architecture named Flat-net and its performance are evaluated and compared with eleven state-of-the-art methods from the literature. The dataset contains midsagittal anatomical Magnetic Resonance Images for 9 speakers sustaining 62 articulations with 21 annotated anatomical landmarks per image. Results show that the Flat-net approach outperforms the former methods, leading to an overall Root Mean Square Error of 3.6 pixels/0.36 cm obtained in a leave-one-out procedure over the speakers. The implementation codes are also shared publicly on GitHub.

Mohammad Eslami, Solale Tabarestani, Shadi Albarqouni et al.

Chest X-ray radiography is one of the earliest medical imaging technologies and remains one of the most widely-used for diagnosis, screening, and treatment follow up of diseases related to lungs and heart. The literature in this field of research reports many interesting studies dealing with the challenging tasks of bone suppression and organ segmentation but performed separately, limiting any learning that comes with the consolidation of parameters that could optimize both processes. This study, and for the first time, introduces a multitask deep learning model that generates simultaneously the bone-suppressed image and the organ-segmented image, enhancing the accuracy of tasks, minimizing the number of parameters needed by the model and optimizing the processing time, all by exploiting the interplay between the network parameters to benefit the performance of both tasks. The architectural design of this model, which relies on a conditional generative adversarial network, reveals the process on how the well-established pix2pix network (image-to-image network) is modified to fit the need for multitasking and extending it to the new image-to-images architecture. The developed source code of this multitask model is shared publicly on Github as the first attempt for providing the two-task pix2pix extension, a supervised/paired/aligned/registered image-to-images translation which would be useful in many multitask applications. Dilated convolutions are also used to improve the results through a more effective receptive field assessment. The comparison with state-of-the-art algorithms along with ablation study and a demonstration video are provided to evaluate efficacy and gauge the merits of the proposed approach.