Lingbo Li

Lingbo Li, Anuradha Mathrani, Teo Susnjak

Assessing risk of bias (RoB) in randomized controlled trials is essential for trustworthy evidence synthesis, but the process is resource-intensive and prone to variability across reviewers. Large language models (LLMs) offer a route to automation, but existing methods rely on manually engineered prompts that are difficult to reproduce, generalize, or evaluate. This study introduces a programmable RoB assessment pipeline that replaces ad-hoc prompt design with structured, code-based optimization using DSPy and its GEPA module. GEPA refines LLM reasoning through Pareto-guided search and produces inspectable execution traces, enabling transparent replication of every step in the optimization process. We evaluated the method on 100 RCTs from published meta-analyses across seven RoB domains. GEPA-generated prompts were applied to both open-weight models (Mistral Small 3.1 with GPT-oss-20b) and commercial models (GPT-5 Nano and GPT-5 Mini). In domains with clearer methodological reporting, such as Random Sequence Generation, GEPA-generated prompts performed best, with similar results for Allocation Concealment and Blinding of Participants, while the commercial model performed slightly better overall. We also compared GEPA with three manually designed prompts using Claude 3.5 Sonnet. GEPA achieved the highest overall accuracy and improved performance by 30%-40% in Random Sequence Generation and Selective Reporting, and showed generally comparable, competitively aligned performance in the other domains relative to manual prompts. These findings suggest that GEPA can produce consistent and reproducible prompts for RoB assessment, supporting the structured and principled use of LLMs in evidence synthesis.

Lingbo Li, Tianle Li, Xinyi He et al.

Intelligent analysis and visualization of tables use techniques to automatically recommend useful knowledge from data, thus freeing users from tedious multi-dimension data mining. While many studies have succeeded in automating recommendations through rules or machine learning, it is difficult to generalize expert knowledge and provide explainable recommendations. In this paper, we present the recommendation of conditional formatting for the first time, together with chart recommendation, to exemplify intelligent table analysis. We propose analytical semantics over tables to uncover common analysis pattern behind user-created analyses. Here, we design analytical semantics by separating data focus from user intent, which extract the user motivation from data and human perspective respectively. Furthermore, the ASTA framework is designed by us to apply analytical semantics to multiple automated recommendations. ASTA framework extracts data features by designing signatures based on expert knowledge, and enables data referencing at field- (chart) or cell-level (conditional formatting) with pre-trained models. Experiments show that our framework achieves recall at top 1 of 62.86% on public chart corpora, outperforming the best baseline about 14%, and achieves 72.31% on the collected corpus ConFormT, validating that ASTA framework is effective in providing accurate and explainable recommendations.

Weibo Zhou, Lingbo Li, Shangsong Liang

The scarcity and high cost of high-quality question-answering (QA) datasets hinder supervised fine-tuning (SFT) for domain-specific large language models (LLMs). To address this, we introduce D-SCoRE, a training-free pipeline that utilizes LLMs and prompt engineering to produce diverse, high-quality QA datasets from arbitrary textual sources. D-SCoRE integrates $\textbf{D}$ocument-centric processing, $\textbf{S}$egmentation, $\textbf{Co}$T $\textbf{R}$easoning, and structured $\textbf{E}$xport to generate QA-COT datasets tailored for domain-aware SFT. Multi-dimensional control mechanisms, such as semantic role transformation, question type balancing, and counterfactual materials, enhance diversity and relevance, overcoming limitations of existing QA generation. LLMs fine-tuned on D-SCoRE-generated QA datasets, and human-annotated QA datasets (SQuAD, Covid-QA) are evaluated on SQuADShifts and Covid-QA test sets, with D-SCoRE outperforming across most domains. D-SCoRE generates six QA-CoT pairs with four-option counterfactual materials per 100-200-word text in 90 seconds using an 8B LLM on consumer-grade hardware. Its simplicity and scalability enable efficient QA generation and high-performance fine-tuning across domains.

Fan Fang, Carmine Ventre, Lingbo Li et al.

Feature importance aims at measuring how crucial each input feature is for model prediction. It is widely used in feature engineering, model selection and explainable artificial intelligence (XAI). In this paper, we propose a new tree-model explanation approach for model selection. Our novel concept leverages the Coefficient of Variation of a feature weight (measured in terms of the contribution of the feature to the prediction) to capture the dispersion of importance over samples. Extensive experimental results show that our novel feature explanation performs better than general cross validation method in model selection both in terms of time efficiency and accuracy performance.

Fan Fang, Waichung Chung, Carmine Ventre et al.

The cryptocurrency market is amongst the fastest-growing of all the financial markets in the world. Unlike traditional markets, such as equities, foreign exchange and commodities, cryptocurrency market is considered to have larger volatility and illiquidity. This paper is inspired by the recent success of using deep learning for stock market prediction. In this work, we analyze and present the characteristics of the cryptocurrency market in a high-frequency setting. In particular, we applied a deep learning approach to predict the direction of the mid-price changes on the upcoming tick. We monitored live tick-level data from $8$ cryptocurrency pairs and applied both statistical and machine learning techniques to provide a live prediction. We reveal that promising results are possible for cryptocurrencies, and in particular, we achieve a consistent $78\%$ accuracy on the prediction of the mid-price movement on live exchange rate of Bitcoins vs US dollars.

Lingbo Li, XianXing Zhang, Mingyuan Zhou et al.

A tree-based dictionary learning model is developed for joint analysis of imagery and associated text. The dictionary learning may be applied directly to the imagery from patches, or to general feature vectors extracted from patches or superpixels (using any existing method for image feature extraction). Each image is associated with a path through the tree (from root to a leaf), and each of the multiple patches in a given image is associated with one node in that path. Nodes near the tree root are shared between multiple paths, representing image characteristics that are common among different types of images. Moving toward the leaves, nodes become specialized, representing details in image classes. If available, words (text) are also jointly modeled, with a path-dependent probability over words. The tree structure is inferred via a nested Dirichlet process, and a retrospective stick-breaking sampler is used to infer the tree depth and width.