Hao Du

Qihua Dong, Hao Du, Ying Song et al.

Medical image registration is a critical task that estimates the spatial correspondence between pairs of images. However, current traditional and deep-learning-based methods rely on similarity measures to generate a deforming field, which often results in disproportionate volume changes in dissimilar regions, especially in tumor regions. These changes can significantly alter the tumor size and underlying anatomy, which limits the practical use of image registration in clinical diagnosis. To address this issue, we have formulated image registration with tumors as a constraint problem that preserves tumor volumes while maximizing image similarity in other normal regions. Our proposed strategy involves a two-stage process. In the first stage, we use similarity-based registration to identify potential tumor regions by their volume change, generating a soft tumor mask accordingly. In the second stage, we propose a volume-preserving registration with a novel adaptive volume-preserving loss that penalizes the change in size adaptively based on the masks calculated from the previous stage. Our approach balances image similarity and volume preservation in different regions, i.e., normal and tumor regions, by using soft tumor masks to adjust the imposition of volume-preserving loss on each one. This ensures that the tumor volume is preserved during the registration process. We have evaluated our strategy on various datasets and network architectures, demonstrating that our method successfully preserves the tumor volume while achieving comparable registration results with state-of-the-art methods. Our codes is available at: \url{https://dddraxxx.github.io/Volume-Preserving-Registration/}.

Houwen Peng, Hao Du, Hongyuan Yu et al.

One-shot weight sharing methods have recently drawn great attention in neural architecture search due to high efficiency and competitive performance. However, weight sharing across models has an inherent deficiency, i.e., insufficient training of subnetworks in hypernetworks. To alleviate this problem, we present a simple yet effective architecture distillation method. The central idea is that subnetworks can learn collaboratively and teach each other throughout the training process, aiming to boost the convergence of individual models. We introduce the concept of prioritized path, which refers to the architecture candidates exhibiting superior performance during training. Distilling knowledge from the prioritized paths is able to boost the training of subnetworks. Since the prioritized paths are changed on the fly depending on their performance and complexity, the final obtained paths are the cream of the crop. We directly select the most promising one from the prioritized paths as the final architecture, without using other complex search methods, such as reinforcement learning or evolution algorithms. The experiments on ImageNet verify such path distillation method can improve the convergence ratio and performance of the hypernetwork, as well as boosting the training of subnetworks. The discovered architectures achieve superior performance compared to the recent MobileNetV3 and EfficientNet families under aligned settings. Moreover, the experiments on object detection and more challenging search space show the generality and robustness of the proposed method. Code and models are available at https://github.com/microsoft/cream.git.