Yuntian Chen

Chengchun Liu, Yuntian Chen, Fanyang Mo

Organic chemistry is undergoing a major paradigm shift, moving from a labor-intensive approach to a new era dominated by automation and artificial intelligence (AI). This transformative shift is being driven by technological advances, the ever-increasing demand for greater research efficiency and accuracy, and the burgeoning growth of interdisciplinary research. AI models, supported by computational power and algorithms, are drastically reshaping synthetic planning and introducing groundbreaking ways to tackle complex molecular synthesis. In addition, autonomous robotic systems are rapidly accelerating the pace of discovery by performing tedious tasks with unprecedented speed and precision. This article examines the multiple opportunities and challenges presented by this paradigm shift and explores its far-reaching implications. It provides valuable insights into the future trajectory of organic chemistry research, which is increasingly defined by the synergistic interaction of automation and AI.

Ding Wang, Yuntian Chen, Shiyi Chen

The rapid expansion of wind power worldwide underscores the critical significance of engineering-focused analytical wake models in both the design and operation of wind farms. These theoretically-derived ana lytical wake models have limited predictive capabilities, particularly in the near-wake region close to the turbine rotor, due to assumptions that do not hold. Knowledge discovery methods can bridge these gaps by extracting insights, adjusting for theoretical assumptions, and developing accurate models for physical processes. In this study, we introduce a genetic symbolic regression (SR) algorithm to discover an interpretable mathematical expression for the mean velocity deficit throughout the wake, a previously unavailable insight. By incorporating a double Gaussian distribution into the SR algorithm as domain knowledge and designing a hierarchical equation structure, the search space is reduced, thus efficiently finding a concise, physically informed, and robust wake model. The proposed mathematical expression (equation) can predict the wake velocity deficit at any location in the full-wake region with high precision and stability. The model's effectiveness and practicality are validated through experimental data and high-fidelity numerical simulations.