ZhenXing Dong

Xueshen Li, Zhenxing Dong, Hongshan Liu et al.

Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based super-resolution technology, which improves the capability of resolving morphological structures. However, existing deep learning-based method only focuses on spatial distribution and disregard frequency fidelity in image reconstruction, leading to a frequency bias. To overcome this limitation, we propose a frequency-aware super-resolution framework that integrates three critical frequency-based modules (i.e., frequency transformation, frequency skip connection, and frequency alignment) and frequency-based loss function into a conditional generative adversarial network (cGAN). We conducted a large-scale quantitative study from an existing coronary OCT dataset to demonstrate the superiority of our proposed framework over existing deep learning frameworks. In addition, we confirmed the generalizability of our framework by applying it to fish corneal images and rat retinal images, demonstrating its capability to super-resolve morphological details in eye imaging.

ZhenXing Dong, JiaZhou Chen, YangHui Xu

The planning of digital orthodontic treatment requires providing tooth alignment, which not only consumes a lot of time and labor to determine manually but also relays clinical experiences heavily. In this work, we proposed a lightweight tooth alignment neural network based on Swin-transformer. We first re-organized 3D point clouds based on virtual arch lines and converted them into order-sorted multi-channel textures, which improves the accuracy and efficiency simultaneously. We then designed two new occlusal loss functions that quantitatively evaluate the occlusal relationship between the upper and lower jaws. They are important clinical constraints, first introduced to the best of our knowledge, and lead to cutting-edge prediction accuracy. To train our network, we collected a large digital orthodontic dataset that has 591 clinical cases, including various complex clinical cases. This dataset will benefit the community after its release since there is no open dataset so far. Furthermore, we also proposed two new orthodontic dataset augmentation methods considering tooth spatial distribution and occlusion. We evaluated our method with this dataset and extensive experiments, including comparisons with STAT methods and ablation studies, and demonstrate the high prediction accuracy of our method.

Zhenxing Dong, Hong Cao, Wang Shen et al.

Current learning-based single image super-resolution (SISR) algorithms underperform on real data due to the deviation in the assumed degrada-tion process from that in the real-world scenario. Conventional degradation processes consider applying blur, noise, and downsampling (typicallybicubic downsampling) on high-resolution (HR) images to synthesize low-resolution (LR) counterparts. However, few works on degradation modelling have taken the physical aspects of the optical imaging system intoconsideration. In this paper, we analyze the imaging system optically andexploit the characteristics of the real-world LR-HR pairs in the spatial frequency domain. We formulate a real-world physics-inspired degradationmodel by considering bothopticsandsensordegradation; The physical degradation of an imaging system is modelled as a low-pass filter, whose cut-off frequency is dictated by the object distance, the focal length of thelens, and the pixel size of the image sensor. In particular, we propose to use a convolutional neural network (CNN) to learn the cutoff frequency of real-world degradation process. The learned network is then applied to synthesize LR images from unpaired HR images. The synthetic HR-LR image pairs are later used to train an SISR network. We evaluatethe effectiveness and generalization capability of the proposed degradation model on real-world images captured by different imaging systems. Experimental results showcase that the SISR network trained by using our synthetic data performs favorably against the network using the traditional degradation model. Moreover, our results are comparable to that obtained by the same network trained by using real-world LR-HR pairs, which are challenging to obtain in real scenes.