Gregorio Rubio

IV
h-index8
3papers
26citations
Novelty30%
AI Score25

3 Papers

13.3IVJan 22, 2024
DeepCERES: A Deep learning method for cerebellar lobule segmentation using ultra-high resolution multimodal MRI

Sergio Morell-Ortega, Marina Ruiz-Perez, Marien Gadea et al.

This paper introduces a novel multimodal and high-resolution human brain cerebellum lobule segmentation method. Unlike current tools that operate at standard resolution ($1 \text{ mm}^{3}$) or using mono-modal data, the proposed method improves cerebellum lobule segmentation through the use of a multimodal and ultra-high resolution ($0.125 \text{ mm}^{3}$) training dataset. To develop the method, first, a database of semi-automatically labelled cerebellum lobules was created to train the proposed method with ultra-high resolution T1 and T2 MR images. Then, an ensemble of deep networks has been designed and developed, allowing the proposed method to excel in the complex cerebellum lobule segmentation task, improving precision while being memory efficient. Notably, our approach deviates from the traditional U-Net model by exploring alternative architectures. We have also integrated deep learning with classical machine learning methods incorporating a priori knowledge from multi-atlas segmentation, which improved precision and robustness. Finally, a new online pipeline, named DeepCERES, has been developed to make available the proposed method to the scientific community requiring as input only a single T1 MR image at standard resolution.

5.1IVJan 28, 2025Code
Ultra-high resolution multimodal MRI densely labelled holistic structural brain atlas

José V. Manjón, Sergio Morell-Ortega, Marina Ruiz-Perez et al.

In this paper, we introduce a novel structural holistic Atlas (holiAtlas) of the human brain anatomy based on multimodal and high-resolution MRI that covers several anatomical levels from the organ to the substructure level, using a new densely labelled protocol generated from the fusion of multiple local protocols at different scales. This atlas was constructed by averaging images and segmentations of 75 healthy subjects from the Human Connectome Project database. Specifically, MR images of T1, T2 and WMn (White Matter nulled) contrasts at 0.125 $mm^{3}$ resolution were selected for this project. The images of these 75 subjects were nonlinearly registered and averaged using symmetric group-wise normalisation to construct the atlas. At the finest level, the proposed atlas has 350 different labels derived from 7 distinct delineation protocols. These labels were grouped at multiple scales, offering a coherent and consistent holistic representation of the brain across different levels of detail. This multiscale and multimodal atlas can be used to develop new ultra-high-resolution segmentation methods, potentially improving the early detection of neurological disorders. We make it publicly available to the scientific community.

9.4ROJun 22, 2017
Context Reasoning in Underwater Robots Using MEBN

Xin Li, José-Fernán Martínez, Gregorio Rubio et al.

This paper presents ongoing research in the SWARMs project towards facilitating context awareness in underwater robots. In particular, the focus of this paper is put on the context reasoning part. The underwater environment introduces uncertainties in context data which lead to difficulties in the context reasoning phase. As probability is the best well-known formalism for computational scientific reasoning under uncertainties, the emerging and effective probabilistic reasoning method, namely, Multi-Entity Bayesian Network (MEBN), is explored for its feasibility to reason under uncertainties in the SWARMs project. A simple use case for oil spill monitoring is used to verify the usefulness of MEBN. The results show that the MEBN is a promising approach to reason about context in the presence of uncertainties in the underwater robot field.