Yuanfan Guo

CV
h-index28
19papers
267citations
Novelty55%
AI Score62

19 Papers

CVMay 26, 2022Code
HIRL: A General Framework for Hierarchical Image Representation Learning

Minghao Xu, Yuanfan Guo, Xuanyu Zhu et al.

Learning self-supervised image representations has been broadly studied to boost various visual understanding tasks. Existing methods typically learn a single level of image semantics like pairwise semantic similarity or image clustering patterns. However, these methods can hardly capture multiple levels of semantic information that naturally exists in an image dataset, e.g., the semantic hierarchy of "Persian cat to cat to mammal" encoded in an image database for species. It is thus unknown whether an arbitrary image self-supervised learning (SSL) approach can benefit from learning such hierarchical semantics. To answer this question, we propose a general framework for Hierarchical Image Representation Learning (HIRL). This framework aims to learn multiple semantic representations for each image, and these representations are structured to encode image semantics from fine-grained to coarse-grained. Based on a probabilistic factorization, HIRL learns the most fine-grained semantics by an off-the-shelf image SSL approach and learns multiple coarse-grained semantics by a novel semantic path discrimination scheme. We adopt six representative image SSL methods as baselines and study how they perform under HIRL. By rigorous fair comparison, performance gain is observed on all the six methods for diverse downstream tasks, which, for the first time, verifies the general effectiveness of learning hierarchical image semantics. All source code and model weights are available at https://github.com/hirl-team/HIRL

CVJul 9, 2024Code
HumanRefiner: Benchmarking Abnormal Human Generation and Refining with Coarse-to-fine Pose-Reversible Guidance

Guian Fang, Wenbiao Yan, Yuanfan Guo et al.

Text-to-image diffusion models have significantly advanced in conditional image generation. However, these models usually struggle with accurately rendering images featuring humans, resulting in distorted limbs and other anomalies. This issue primarily stems from the insufficient recognition and evaluation of limb qualities in diffusion models. To address this issue, we introduce AbHuman, the first large-scale synthesized human benchmark focusing on anatomical anomalies. This benchmark consists of 56K synthesized human images, each annotated with detailed, bounding-box level labels identifying 147K human anomalies in 18 different categories. Based on this, the recognition of human anomalies can be established, which in turn enhances image generation through traditional techniques such as negative prompting and guidance. To further boost the improvement, we propose HumanRefiner, a novel plug-and-play approach for the coarse-to-fine refinement of human anomalies in text-to-image generation. Specifically, HumanRefiner utilizes a self-diagnostic procedure to detect and correct issues related to both coarse-grained abnormal human poses and fine-grained anomaly levels, facilitating pose-reversible diffusion generation. Experimental results on the AbHuman benchmark demonstrate that HumanRefiner significantly reduces generative discrepancies, achieving a 2.9x improvement in limb quality compared to the state-of-the-art open-source generator SDXL and a 1.4x improvement over DALL-E 3 in human evaluations. Our data and code are available at https://github.com/Enderfga/HumanRefiner.

LGJun 3
Differentiable Efficient Operator Search

Xiaohuan Pei, Jiyuan Zhang, Yuanfan Guo et al.

Efficient multimodal foundation models often rely on manually designed token-reduction operators, such as pruning, merging, pooling, and adaptive reweighting. Although these operators appear different, we show that they can be interpreted as distinct regimes of a shared operator space. Based on this view, we introduce Efficient Operator Search, a differentiable framework that jointly searches where to reduce tokens, how many tokens to retain, and how reduced token information should be processed. The proposed search space parameterizes layer activation, retention budget, and operator behavior, while the search policy optimizes task performance under one-sided budget and cost constraints. This formulation recovers representative hand-designed baselines as special cases and further discovers hybrid operators beyond isolated manual designs. Experiments on multimodal benchmarks show that the searched operators achieve competitive accuracy-efficiency trade-offs, especially under aggressive visual-token reduction. These results suggest that efficient multimodal inference can be reframed from manual operator design to differentiable operator search.

LGNov 23, 2022Code
EurNet: Efficient Multi-Range Relational Modeling of Spatial Multi-Relational Data

Minghao Xu, Yuanfan Guo, Yi Xu et al.

Modeling spatial relationship in the data remains critical across many different tasks, such as image classification, semantic segmentation and protein structure understanding. Previous works often use a unified solution like relative positional encoding. However, there exists different kinds of spatial relations, including short-range, medium-range and long-range relations, and modeling them separately can better capture the focus of different tasks on the multi-range relations (e.g., short-range relations can be important in instance segmentation, while long-range relations should be upweighted for semantic segmentation). In this work, we introduce the EurNet for Efficient multi-range relational modeling. EurNet constructs the multi-relational graph, where each type of edge corresponds to short-, medium- or long-range spatial interactions. In the constructed graph, EurNet adopts a novel modeling layer, called gated relational message passing (GRMP), to propagate multi-relational information across the data. GRMP captures multiple relations within the data with little extra computational cost. We study EurNets in two important domains for image and protein structure modeling. Extensive experiments on ImageNet classification, COCO object detection and ADE20K semantic segmentation verify the gains of EurNet over the previous SoTA FocalNet. On the EC and GO protein function prediction benchmarks, EurNet consistently surpasses the previous SoTA GearNet. Our results demonstrate the strength of EurNets on modeling spatial multi-relational data from various domains. The implementations of EurNet for image modeling are available at https://github.com/hirl-team/EurNet-Image . The implementations for other applied domains/tasks will be released soon.

CVAug 31, 2023
Any-Size-Diffusion: Toward Efficient Text-Driven Synthesis for Any-Size HD Images

Qingping Zheng, Yuanfan Guo, Jiankang Deng et al.

Stable diffusion, a generative model used in text-to-image synthesis, frequently encounters resolution-induced composition problems when generating images of varying sizes. This issue primarily stems from the model being trained on pairs of single-scale images and their corresponding text descriptions. Moreover, direct training on images of unlimited sizes is unfeasible, as it would require an immense number of text-image pairs and entail substantial computational expenses. To overcome these challenges, we propose a two-stage pipeline named Any-Size-Diffusion (ASD), designed to efficiently generate well-composed images of any size, while minimizing the need for high-memory GPU resources. Specifically, the initial stage, dubbed Any Ratio Adaptability Diffusion (ARAD), leverages a selected set of images with a restricted range of ratios to optimize the text-conditional diffusion model, thereby improving its ability to adjust composition to accommodate diverse image sizes. To support the creation of images at any desired size, we further introduce a technique called Fast Seamless Tiled Diffusion (FSTD) at the subsequent stage. This method allows for the rapid enlargement of the ASD output to any high-resolution size, avoiding seaming artifacts or memory overloads. Experimental results on the LAION-COCO and MM-CelebA-HQ benchmarks demonstrate that ASD can produce well-structured images of arbitrary sizes, cutting down the inference time by 2x compared to the traditional tiled algorithm.

CVAug 23, 2024
EasyControl: Transfer ControlNet to Video Diffusion for Controllable Generation and Interpolation

Cong Wang, Jiaxi Gu, Panwen Hu et al.

Following the advancements in text-guided image generation technology exemplified by Stable Diffusion, video generation is gaining increased attention in the academic community. However, relying solely on text guidance for video generation has serious limitations, as videos contain much richer content than images, especially in terms of motion. This information can hardly be adequately described with plain text. Fortunately, in computer vision, various visual representations can serve as additional control signals to guide generation. With the help of these signals, video generation can be controlled in finer detail, allowing for greater flexibility for different applications. Integrating various controls, however, is nontrivial. In this paper, we propose a universal framework called EasyControl. By propagating and injecting condition features through condition adapters, our method enables users to control video generation with a single condition map. With our framework, various conditions including raw pixels, depth, HED, etc., can be integrated into different Unet-based pre-trained video diffusion models at a low practical cost. We conduct comprehensive experiments on public datasets, and both quantitative and qualitative results indicate that our method outperforms state-of-the-art methods. EasyControl significantly improves various evaluation metrics across multiple validation datasets compared to previous works. Specifically, for the sketch-to-video generation task, EasyControl achieves an improvement of 152.0 on FVD and 19.9 on IS, respectively, in UCF101 compared with VideoComposer. For fidelity, our model demonstrates powerful image retention ability, resulting in high FVD and IS in UCF101 and MSR-VTT compared to other image-to-video models.

CVFeb 3
SlowFocus: Enhancing Fine-grained Temporal Understanding in Video LLM

Ming Nie, Dan Ding, Chunwei Wang et al.

Large language models (LLMs) have demonstrated exceptional capabilities in text understanding, which has paved the way for their expansion into video LLMs (Vid-LLMs) to analyze video data. However, current Vid-LLMs struggle to simultaneously retain high-quality frame-level semantic information (i.e., a sufficient number of tokens per frame) and comprehensive video-level temporal information (i.e., an adequate number of sampled frames per video). This limitation hinders the advancement of Vid-LLMs towards fine-grained video understanding. To address this issue, we introduce the SlowFocus mechanism, which significantly enhances the equivalent sampling frequency without compromising the quality of frame-level visual tokens. SlowFocus begins by identifying the query-related temporal segment based on the posed question, then performs dense sampling on this segment to extract local high-frequency features. A multi-frequency mixing attention module is further leveraged to aggregate these local high-frequency details with global low-frequency contexts for enhanced temporal comprehension. Additionally, to tailor Vid-LLMs to this innovative mechanism, we introduce a set of training strategies aimed at bolstering both temporal grounding and detailed temporal reasoning capabilities. Furthermore, we establish FineAction-CGR, a benchmark specifically devised to assess the ability of Vid-LLMs to process fine-grained temporal understanding tasks. Comprehensive experiments demonstrate the superiority of our mechanism across both existing public video understanding benchmarks and our proposed FineAction-CGR.

IVApr 18, 2022
Enhancing Non-mass Breast Ultrasound Cancer Classification With Knowledge Transfer

Yangrun Hu, Yuanfan Guo, Fan Zhang et al.

Much progress has been made in the deep neural network (DNN) based diagnosis of mass lesions breast ultrasound (BUS) images. However, the non-mass lesion is less investigated because of the limited data. Based on the insight that mass data is sufficient and shares the same knowledge structure with non-mass data of identifying the malignancy of a lesion based on the ultrasound image, we propose a novel transfer learning framework to enhance the generalizability of the DNN model for non-mass BUS with the help of mass BUS. Specifically, we train a shared DNN with combined non-mass and mass data. With the prior of different marginal distributions in input and output space, we employ two domain alignment strategies in the proposed transfer learning framework with the insight of capturing domain-specific distribution to address the issue of domain shift. Moreover, we propose a cross-domain semantic-preserve data generation module called CrossMix to recover the missing distribution between non-mass and mass data that is not presented in training data. Experimental results on an in-house dataset demonstrate that the DNN model trained with combined data by our framework achieves a 10% improvement in AUC on the malignancy prediction task of non-mass BUS compared to training directly on non-mass data.

CVMay 25
AnE: Pushing the Reasoning Frontier of Multimodal LLMs via Anchor Evolution

Zehao Wang, Yihan Zeng, Zidong Gong et al.

Post-training via Supervised Fine-Tuning (SFT) and Reinforcement Learning (RL) is crucial for enhancing reasoning in Multimodal Large Language Models (MLLMs), yet existing paradigms often reach a performance bottleneck due to the limitations of static data. While current methods leverage self-reflection or self-evolution to push these boundaries, they still suffer from cognitive drift and hallucinated reasoning paths caused by low-quality synthetic data. To address these challenges, we propose Anchor Evolution (AnE), a new paradigm that integrates truth-anchored data curation and model evolution, achieving faithful and steady performance gains at the reasoning frontier. Specifically, we propose Truth Anchor Expansion, which pinpoints the model failing frontier via trajectory rollouts and leverages ground-truth databases to retrieve high-fidelity anchors for faithful data curation. Subsequently, we introduce the Scaffold-Stripping Mechanism to internalize reasoning capabilities. This mechanism first anchors reasoning paths via scaffold-augmented supervision to mitigate the learning complexity and distribution drift of direct SFT on raw data, then leverages RL to strip the scaffold template, thereby effectively transitioning the reasoning paths into intrinsic model capabilities. Experimental results on multimodal reasoning benchmarks show that our method substantially advances the model performance frontier, improving the base model by 10.3\% across eight multimodal benchmarks and achieving state-of-the-art results. The code will be made publicly available.

IVApr 18, 2022
Self Supervised Lesion Recognition For Breast Ultrasound Diagnosis

Yuanfan Guo, Canqian Yang, Tiancheng Lin et al.

Previous deep learning based Computer Aided Diagnosis (CAD) system treats multiple views of the same lesion as independent images. Since an ultrasound image only describes a partial 2D projection of a 3D lesion, such paradigm ignores the semantic relationship between different views of a lesion, which is inconsistent with the traditional diagnosis where sonographers analyze a lesion from at least two views. In this paper, we propose a multi-task framework that complements Benign/Malignant classification task with lesion recognition (LR) which helps leveraging relationship among multiple views of a single lesion to learn a complete representation of the lesion. To be specific, LR task employs contrastive learning to encourage representation that pulls multiple views of the same lesion and repels those of different lesions. The task therefore facilitates a representation that is not only invariant to the view change of the lesion, but also capturing fine-grained features to distinguish between different lesions. Experiments show that the proposed multi-task framework boosts the performance of Benign/Malignant classification as two sub-tasks complement each other and enhance the learned representation of ultrasound images.

IVMar 25, 2024Code
Self-Adaptive Reality-Guided Diffusion for Artifact-Free Super-Resolution

Qingping Zheng, Ling Zheng, Yuanfan Guo et al.

Artifact-free super-resolution (SR) aims to translate low-resolution images into their high-resolution counterparts with a strict integrity of the original content, eliminating any distortions or synthetic details. While traditional diffusion-based SR techniques have demonstrated remarkable abilities to enhance image detail, they are prone to artifact introduction during iterative procedures. Such artifacts, ranging from trivial noise to unauthentic textures, deviate from the true structure of the source image, thus challenging the integrity of the super-resolution process. In this work, we propose Self-Adaptive Reality-Guided Diffusion (SARGD), a training-free method that delves into the latent space to effectively identify and mitigate the propagation of artifacts. Our SARGD begins by using an artifact detector to identify implausible pixels, creating a binary mask that highlights artifacts. Following this, the Reality Guidance Refinement (RGR) process refines artifacts by integrating this mask with realistic latent representations, improving alignment with the original image. Nonetheless, initial realistic-latent representations from lower-quality images result in over-smoothing in the final output. To address this, we introduce a Self-Adaptive Guidance (SAG) mechanism. It dynamically computes a reality score, enhancing the sharpness of the realistic latent. These alternating mechanisms collectively achieve artifact-free super-resolution. Extensive experiments demonstrate the superiority of our method, delivering detailed artifact-free high-resolution images while reducing sampling steps by 2X. We release our code at https://github.com/ProAirVerse/Self-Adaptive-Guidance-Diffusion.git.

CVSep 14, 2025Code
GLaVE-Cap: Global-Local Aligned Video Captioning with Vision Expert Integration

Wan Xu, Feng Zhu, Yihan Zeng et al.

Video detailed captioning aims to generate comprehensive video descriptions to facilitate video understanding. Recently, most efforts in the video detailed captioning community have been made towards a local-to-global paradigm, which first generates local captions from video clips and then summarizes them into a global caption. However, we find this paradigm leads to less detailed and contextual-inconsistent captions, which can be attributed to (1) no mechanism to ensure fine-grained captions, and (2) weak interaction between local and global captions. To remedy the above two issues, we propose GLaVE-Cap, a Global-Local aligned framework with Vision Expert integration for Captioning, which consists of two core modules: TrackFusion enables comprehensive local caption generation, by leveraging vision experts to acquire cross-frame visual prompts, coupled with a dual-stream structure; while CaptionBridge establishes a local-global interaction, by using global context to guide local captioning, and adaptively summarizing local captions into a coherent global caption. Besides, we construct GLaVE-Bench, a comprehensive video captioning benchmark featuring 5X more queries per video than existing benchmarks, covering diverse visual dimensions to facilitate reliable evaluation. We further provide a training dataset GLaVE-1.2M containing 16K high-quality fine-grained video captions and 1.2M related question-answer pairs. Extensive experiments on four benchmarks show that our GLaVE-Cap achieves state-of-the-art performance. Besides, the ablation studies and student model analyses further validate the effectiveness of the proposed modules and the contribution of GLaVE-1.2M to the video understanding community. The source code, model weights, benchmark, and dataset will be open-sourced.

CVFeb 1, 2022Code
HCSC: Hierarchical Contrastive Selective Coding

Yuanfan Guo, Minghao Xu, Jiawen Li et al.

Hierarchical semantic structures naturally exist in an image dataset, in which several semantically relevant image clusters can be further integrated into a larger cluster with coarser-grained semantics. Capturing such structures with image representations can greatly benefit the semantic understanding on various downstream tasks. Existing contrastive representation learning methods lack such an important model capability. In addition, the negative pairs used in these methods are not guaranteed to be semantically distinct, which could further hamper the structural correctness of learned image representations. To tackle these limitations, we propose a novel contrastive learning framework called Hierarchical Contrastive Selective Coding (HCSC). In this framework, a set of hierarchical prototypes are constructed and also dynamically updated to represent the hierarchical semantic structures underlying the data in the latent space. To make image representations better fit such semantic structures, we employ and further improve conventional instance-wise and prototypical contrastive learning via an elaborate pair selection scheme. This scheme seeks to select more diverse positive pairs with similar semantics and more precise negative pairs with truly distinct semantics. On extensive downstream tasks, we verify the superior performance of HCSC over state-of-the-art contrastive methods, and the effectiveness of major model components is proved by plentiful analytical studies. We build a comprehensive model zoo in Sec. D. Our source code and model weights are available at https://github.com/gyfastas/HCSC

CVDec 27, 2023
PanGu-Draw: Advancing Resource-Efficient Text-to-Image Synthesis with Time-Decoupled Training and Reusable Coop-Diffusion

Guansong Lu, Yuanfan Guo, Jianhua Han et al.

Current large-scale diffusion models represent a giant leap forward in conditional image synthesis, capable of interpreting diverse cues like text, human poses, and edges. However, their reliance on substantial computational resources and extensive data collection remains a bottleneck. On the other hand, the integration of existing diffusion models, each specialized for different controls and operating in unique latent spaces, poses a challenge due to incompatible image resolutions and latent space embedding structures, hindering their joint use. Addressing these constraints, we present "PanGu-Draw", a novel latent diffusion model designed for resource-efficient text-to-image synthesis that adeptly accommodates multiple control signals. We first propose a resource-efficient Time-Decoupling Training Strategy, which splits the monolithic text-to-image model into structure and texture generators. Each generator is trained using a regimen that maximizes data utilization and computational efficiency, cutting data preparation by 48% and reducing training resources by 51%. Secondly, we introduce "Coop-Diffusion", an algorithm that enables the cooperative use of various pre-trained diffusion models with different latent spaces and predefined resolutions within a unified denoising process. This allows for multi-control image synthesis at arbitrary resolutions without the necessity for additional data or retraining. Empirical validations of Pangu-Draw show its exceptional prowess in text-to-image and multi-control image generation, suggesting a promising direction for future model training efficiencies and generation versatility. The largest 5B T2I PanGu-Draw model is released on the Ascend platform. Project page: $\href{https://pangu-draw.github.io}{this~https~URL}$

CVJan 6, 2025
Brick-Diffusion: Generating Long Videos with Brick-to-Wall Denoising

Yunlong Yuan, Yuanfan Guo, Chunwei Wang et al.

Recent advances in diffusion models have greatly improved text-driven video generation. However, training models for long video generation demands significant computational power and extensive data, leading most video diffusion models to be limited to a small number of frames. Existing training-free methods that attempt to generate long videos using pre-trained short video diffusion models often struggle with issues such as insufficient motion dynamics and degraded video fidelity. In this paper, we present Brick-Diffusion, a novel, training-free approach capable of generating long videos of arbitrary length. Our method introduces a brick-to-wall denoising strategy, where the latent is denoised in segments, with a stride applied in subsequent iterations. This process mimics the construction of a staggered brick wall, where each brick represents a denoised segment, enabling communication between frames and improving overall video quality. Through quantitative and qualitative evaluations, we demonstrate that Brick-Diffusion outperforms existing baseline methods in generating high-fidelity videos.

CVOct 16, 2025
VTimeCoT: Thinking by Drawing for Video Temporal Grounding and Reasoning

Jinglei Zhang, Yuanfan Guo, Rolandos Alexandros Potamias et al.

In recent years, video question answering based on multimodal large language models (MLLM) has garnered considerable attention, due to the benefits from the substantial advancements in LLMs. However, these models have a notable deficiency in the domains of video temporal grounding and reasoning, posing challenges to the development of effective real-world video understanding systems. Inspired by how humans use video players to interact with the progress bar for video comprehension, we introduce VTimeCoT, a simple yet effective training-free framework, designed for high-performance video grounding and reasoning. The proposed framework incorporates two novel visual tools of the progress bar: a plug-and-play progress bar integration tool and a high-efficiency highlighting tool. In addition, to address the limitations of conventional text-based chain-of-thought (CoT) approaches, we introduce a visuotemporal CoT process that integrates cross-modality reasoning across both video and text. Our approach demonstrates significant performance improvements on both Qwen2VL-7B and GPT4o baselines in tasks of video temporal grounding and reasoning-based question answering. Finally, we showcase that the proposed framework achieves a compositional and interpretable reasoning process. Project page: https://vtimecot.github.io

CVOct 13, 2025
Multiview Manifold Evidential Fusion for PolSAR Image Classification

Junfei Shi, Haojia Zhang, Haiyan Jin et al.

Polarimetric Synthetic Aperture Radar (PolSAR) covariance matrices and their extracted multi-features - such as scattering angle, entropy, texture, and boundary descriptors - provide complementary and physically interpretable information for image classification. Traditional fusion strategies typically concatenate these features or employ deep learning networks to combine them. However, the covariance matrices and multi-features, as two complementary views, lie on different manifolds with distinct geometric structures. Existing fusion methods also overlook the varying importance of different views and ignore uncertainty, often leading to unreliable predictions. To address these issues, we propose a Multiview Manifold Evidential Fusion (MMEFnet) method to effectively fuse these two views. It gives a new framework to integrate PolSAR manifold learning and evidence fusion into a unified architecture. Specifically, covariance matrices are represented on the Hermitian Positive Definite (HPD) manifold, while multi-features are modeled on the Grassmann manifold. Two different kernel metric learning networks are constructed to learn their manifold representations. Subsequently, a trusted multiview evidence fusion, replacing the conventional softmax classifier, estimates belief mass and quantifies the uncertainty of each view from the learned deep features. Finally, a Dempster-Shafer theory-based fusion strategy combines evidence, enabling a more reliable and interpretable classification. Extensive experiments on three real-world PolSAR datasets demonstrate that the proposed method consistently outperforms existing approaches in accuracy, robustness, and interpretability.

LGAug 25, 2025
TiKMiX: Take Data Influence into Dynamic Mixture for Language Model Pre-training

Yifan Wang, Binbin Liu, Fengze Liu et al.

The data mixture used in the pre-training of a language model is a cornerstone of its final performance. However, a static mixing strategy is suboptimal, as the model's learning preferences for various data domains shift dynamically throughout training. Crucially, observing these evolving preferences in a computationally efficient manner remains a significant challenge. To address this, we propose TiKMiX, a method that dynamically adjusts the data mixture according to the model's evolving preferences. TiKMiX introduces Group Influence, an efficient metric for evaluating the impact of data domains on the model. This metric enables the formulation of the data mixing problem as a search for an optimal, influence-maximizing distribution. We solve this via two approaches: TiKMiX-D for direct optimization, and TiKMiX-M, which uses a regression model to predict a superior mixture. We trained models with different numbers of parameters, on up to 1 trillion tokens. TiKMiX-D exceeds the performance of state-of-the-art methods like REGMIX while using just 20% of the computational resources. TiKMiX-M leads to an average performance gain of 2% across 9 downstream benchmarks. Our experiments reveal that a model's data preferences evolve with training progress and scale, and we demonstrate that dynamically adjusting the data mixture based on Group Influence, a direct measure of these preferences, significantly improves performance by mitigating the underdigestion of data seen with static ratios.

CVApr 9, 2020
Decoupled Gradient Harmonized Detector for Partial Annotation: Application to Signet Ring Cell Detection

Tiancheng Lin, Yuanfan Guo, Canqian Yang et al.

Early diagnosis of signet ring cell carcinoma dramatically improves the survival rate of patients. Due to lack of public dataset and expert-level annotations, automatic detection on signet ring cell (SRC) has not been thoroughly investigated. In MICCAI DigestPath2019 challenge, apart from foreground (SRC region)-background (normal tissue area) class imbalance, SRCs are partially annotated due to costly medical image annotation, which introduces extra label noise. To address the issues simultaneously, we propose Decoupled Gradient Harmonizing Mechanism (DGHM) and embed it into classification loss, denoted as DGHM-C loss. Specifically, besides positive (SRCs) and negative (normal tissues) examples, we further decouple noisy examples from clean examples and harmonize the corresponding gradient distributions in classification respectively. Without whistles and bells, we achieved the 2nd place in the challenge. Ablation studies and controlled label missing rate experiments demonstrate that DGHM-C loss can bring substantial improvement in partially annotated object detection.