Yufei Zhou

Tong Xie, Yuwei Wan, Wei Huang et al.

The amount of data has growing significance in exploring cutting-edge materials and a number of datasets have been generated either by hand or automated approaches. However, the materials science field struggles to effectively utilize the abundance of data, especially in applied disciplines where materials are evaluated based on device performance rather than their properties. This article presents a new natural language processing (NLP) task called structured information inference (SII) to address the complexities of information extraction at the device level in materials science. We accomplished this task by tuning GPT-3 on an existing perovskite solar cell FAIR (Findable, Accessible, Interoperable, Reusable) dataset with 91.8% F1-score and extended the dataset with data published since its release. The produced data is formatted and normalized, enabling its direct utilization as input in subsequent data analysis. This feature empowers materials scientists to develop models by selecting high-quality review articles within their domain. Additionally, we designed experiments to predict the electrical performance of solar cells and design materials or devices with targeted parameters using large language models (LLMs). Our results demonstrate comparable performance to traditional machine learning methods without feature selection, highlighting the potential of LLMs to acquire scientific knowledge and design new materials akin to materials scientists.

Ke Chen, Yifeng Wang, Yufei Zhou et al. · cmu

In the field of Alzheimer's disease diagnosis, segmentation and classification tasks are inherently interconnected. Sharing knowledge between models for these tasks can significantly improve training efficiency, particularly when training data is scarce. However, traditional knowledge distillation techniques often struggle to bridge the gap between segmentation and classification due to the distinct nature of tasks and different model architectures. To address this challenge, we propose a dual-stream pipeline that facilitates cross-task and cross-architecture knowledge sharing. Our approach introduces a dual-stream embedding module that unifies feature representations from segmentation and classification models, enabling dimensional integration of these features to guide the classification model. We validated our method on multiple 3D datasets for Alzheimer's disease diagnosis, demonstrating significant improvements in classification performance, especially on small datasets. Furthermore, we extended our pipeline with a residual temporal attention mechanism for early diagnosis, utilizing images taken before the atrophy of patients' brain mass. This advancement shows promise in enabling diagnosis approximately six months earlier in mild and asymptomatic stages, offering critical time for intervention.

Bin Xu, Yufei Zhou, Boling Song et al.

We propose a Hierarchical Multi-scale Knowledge-aware Graph Network (HMKGN) that models multi-scale interactions and spatially hierarchical relationships within whole-slide images (WSIs) for cancer prognostication. Unlike conventional attention-based MIL, which ignores spatial organization, or graph-based MIL, which relies on static handcrafted graphs, HMKGN enforces a hierarchical structure with spatial locality constraints, wherein local cellular-level dynamic graphs aggregate spatially proximate patches within each region of interest (ROI) and a global slide-level dynamic graph integrates ROI-level features into WSI-level representations. Moreover, multi-scale integration at the ROI level combines coarse contextual features from broader views with fine-grained structural representations from local patch-graph aggregation. We evaluate HMKGN on four TCGA cohorts (KIRC, LGG, PAAD, and STAD; N=513, 487, 138, and 370) for survival prediction. It consistently outperforms existing MIL-based models, yielding improved concordance indices (10.85% better) and statistically significant stratification of patient survival risk (log-rank p < 0.05).