16.6IVJul 17, 2024
Applying Conditional Generative Adversarial Networks for Imaging DiagnosisHaowei Yang, Yuxiang Hu, Shuyao He et al.
This study introduces an innovative application of Conditional Generative Adversarial Networks (C-GAN) integrated with Stacked Hourglass Networks (SHGN) aimed at enhancing image segmentation, particularly in the challenging environment of medical imaging. We address the problem of overfitting, common in deep learning models applied to complex imaging datasets, by augmenting data through rotation and scaling. A hybrid loss function combining L1 and L2 reconstruction losses, enriched with adversarial training, is introduced to refine segmentation processes in intravascular ultrasound (IVUS) imaging. Our approach is unique in its capacity to accurately delineate distinct regions within medical images, such as tissue boundaries and vascular structures, without extensive reliance on domain-specific knowledge. The algorithm was evaluated using a standard medical image library, showing superior performance metrics compared to existing methods, thereby demonstrating its potential in enhancing automated medical diagnostics through deep learning
13.0LGNov 26, 2025
Machine Learning Approaches to Clinical Risk Prediction: Multi-Scale Temporal Alignment in Electronic Health RecordsWei-Chen Chang, Lu Dai, Ting Xu
This study proposes a risk prediction method based on a Multi-Scale Temporal Alignment Network (MSTAN) to address the challenges of temporal irregularity, sampling interval differences, and multi-scale dynamic dependencies in Electronic Health Records (EHR). The method focuses on temporal feature modeling by introducing a learnable temporal alignment mechanism and a multi-scale convolutional feature extraction structure to jointly model long-term trends and short-term fluctuations in EHR sequences. At the input level, the model maps multi-source clinical features into a unified high-dimensional semantic space and employs temporal embedding and alignment modules to dynamically weight irregularly sampled data, reducing the impact of temporal distribution differences on model performance. The multi-scale feature extraction module then captures key patterns across different temporal granularities through multi-layer convolution and hierarchical fusion, achieving a fine-grained representation of patient states. Finally, an attention-based aggregation mechanism integrates global temporal dependencies to generate individual-level risk representations for disease risk prediction and health status assessment. Experiments conducted on publicly available EHR datasets show that the proposed model outperforms mainstream baselines in accuracy, recall, precision, and F1-Score, demonstrating the effectiveness and robustness of multi-scale temporal alignment in complex medical time-series analysis. This study provides a new solution for intelligent representation of high-dimensional asynchronous medical sequences and offers important technical support for EHR-driven clinical risk prediction.