Kun Han

Arghavan Rezvani, Xiangyi Yan, Anthony T. Wu et al.

In this study, we propose MoME, a Mixture of Visual Language Medical Experts, for Medical Image Segmentation. MoME adapts the successful Mixture of Experts (MoE) paradigm, widely used in Large Language Models (LLMs), for medical vision-language tasks. The architecture enables dynamic expert selection by effectively utilizing multi-scale visual features tailored to the intricacies of medical imagery, enriched with textual embeddings. This work explores a novel integration of vision-language models for this domain. Utilizing an assembly of 10 datasets, encompassing 3,410 CT scans, MoME demonstrates strong performance on a comprehensive medical imaging segmentation benchmark. Our approach explores the integration of foundation models for medical imaging, benefiting from the established efficacy of MoE in boosting model performance by incorporating textual information. Demonstrating competitive precision across multiple datasets, MoME explores a novel architecture for achieving robust results in medical image analysis.

Pooya Khosravi, Kun Han, Anthony T. Wu et al.

Optical Coherence Tomography Angiography (OCTA) and its derived en-face projections provide high-resolution visualization of the retinal and choroidal vasculature, which is critical for the rapid and accurate diagnosis of retinal diseases. However, acquiring high-quality OCTA images is challenging due to motion sensitivity and the high costs associated with software modifications for conventional OCT devices. Moreover, current deep learning methods for OCT-to-OCTA translation often overlook the vascular differences across retinal layers and struggle to reconstruct the intricate, dense vascular details necessary for reliable diagnosis. To overcome these limitations, we propose XOCT, a novel deep learning framework that integrates Cross-Dimensional Supervision (CDS) with a Multi-Scale Feature Fusion (MSFF) network for layer-aware vascular reconstruction. Our CDS module leverages 2D layer-wise en-face projections, generated via segmentation-weighted z-axis averaging, as supervisory signals to compel the network to learn distinct representations for each retinal layer through fine-grained, targeted guidance. Meanwhile, the MSFF module enhances vessel delineation through multi-scale feature extraction combined with a channel reweighting strategy, effectively capturing vascular details at multiple spatial scales. Our experiments on the OCTA-500 dataset demonstrate XOCT's improvements, especially for the en-face projections which are significant for clinical evaluation of retinal pathologies, underscoring its potential to enhance OCTA accessibility, reliability, and diagnostic value for ophthalmic disease detection and monitoring. The code is available at https://github.com/uci-cbcl/XOCT.

Boliang Zhang, Ying Lyu, Ning Ding et al.

This paper describes our submission for the End-to-end Multi-domain Task Completion Dialog shared task at the 9th Dialog System Technology Challenge (DSTC-9). Participants in the shared task build an end-to-end task completion dialog system which is evaluated by human evaluation and a user simulator based automatic evaluation. Different from traditional pipelined approaches where modules are optimized individually and suffer from cascading failure, we propose an end-to-end dialog system that 1) uses Generative Pretraining 2 (GPT-2) as the backbone to jointly solve Natural Language Understanding, Dialog State Tracking, and Natural Language Generation tasks, 2) adopts Domain and Task Adaptive Pretraining to tailor GPT-2 to the dialog domain before finetuning, 3) utilizes heuristic pre/post-processing rules that greatly simplify the prediction tasks and improve generalizability, and 4) equips a fault tolerance module to correct errors and inappropriate responses. Our proposed method significantly outperforms baselines and ties for first place in the official evaluation. We make our source code publicly available.

Hao Tang, Xingwei Liu, Kun Han et al.

Multi-organ segmentation is one of most successful applications of deep learning in medical image analysis. Deep convolutional neural nets (CNNs) have shown great promise in achieving clinically applicable image segmentation performance on CT or MRI images. State-of-the-art CNN segmentation models apply either 2D or 3D convolutions on input images, with pros and cons associated with each method: 2D convolution is fast, less memory-intensive but inadequate for extracting 3D contextual information from volumetric images, while the opposite is true for 3D convolution. To fit a 3D CNN model on CT or MRI images on commodity GPUs, one usually has to either downsample input images or use cropped local regions as inputs, which limits the utility of 3D models for multi-organ segmentation. In this work, we propose a new framework for combining 3D and 2D models, in which the segmentation is realized through high-resolution 2D convolutions, but guided by spatial contextual information extracted from a low-resolution 3D model. We implement a self-attention mechanism to control which 3D features should be used to guide 2D segmentation. Our model is light on memory usage but fully equipped to take 3D contextual information into account. Experiments on multiple organ segmentation datasets demonstrate that by taking advantage of both 2D and 3D models, our method is consistently outperforms existing 2D and 3D models in organ segmentation accuracy, while being able to directly take raw whole-volume image data as inputs.

Lu Zheng, Zhao Tan, Kun Han et al.

Facebook Marketplace is quickly gaining momentum among consumers as a favored customer-to-customer (C2C) product trading platform. The recommendation system behind it helps to significantly improve the user experience. Building the recommendation system for Facebook Marketplace is challenging for two reasons: 1) Scalability: the number of products in Facebook Marketplace is huge. Tens of thousands of products need to be scored and recommended within a couple hundred milliseconds for millions of users every day; 2) Cold start: the life span of the C2C products is very short and the user activities on the products are sparse. Thus it is difficult to accumulate enough product level signals for recommendation and we are facing a significant cold start issue. In this paper, we propose to address both the scalability and the cold-start issue by building a collaborative multi-modal deep learning based retrieval system where the compact embeddings for the users and the products are trained with the multi-modal content information. This system shows significant improvement over the benchmark in online and off-line experiments: In the online experiment, it increases the number of messages initiated by the buyer to the seller by +26.95%; in the off-line experiment, it improves the prediction accuracy by +9.58%.