3.6CVNov 15, 2025
FaNe: Towards Fine-Grained Cross-Modal Contrast with False-Negative Reduction and Text-Conditioned Sparse AttentionPeng Zhang, Zhihui Lai, Wenting Chen et al.
Medical vision-language pre-training (VLP) offers significant potential for advancing medical image understanding by leveraging paired image-report data. However, existing methods are limited by Fa}lse Negatives (FaNe) induced by semantically similar texts and insufficient fine-grained cross-modal alignment. To address these limitations, we propose FaNe, a semantic-enhanced VLP framework. To mitigate false negatives, we introduce a semantic-aware positive pair mining strategy based on text-text similarity with adaptive normalization. Furthermore, we design a text-conditioned sparse attention pooling module to enable fine-grained image-text alignment through localized visual representations guided by textual cues. To strengthen intra-modal discrimination, we develop a hard-negative aware contrastive loss that adaptively reweights semantically similar negatives. Extensive experiments on five downstream medical imaging benchmarks demonstrate that FaNe achieves state-of-the-art performance across image classification, object detection, and semantic segmentation, validating the effectiveness of our framework.
Prototype Contrastive Consistency Learning for Semi-Supervised Medical Image SegmentationShihuan He, Zhihui Lai, Ruxin Wang et al.
Medical image segmentation is a crucial task in medical image analysis, but it can be very challenging especially when there are less labeled data but with large unlabeled data. Contrastive learning has proven to be effective for medical image segmentation in semi-supervised learning by constructing contrastive samples from partial pixels. However, although previous contrastive learning methods can mine semantic information from partial pixels within images, they ignore the whole context information of unlabeled images, which is very important to precise segmentation. In order to solve this problem, we propose a novel prototype contrastive learning method called Prototype Contrastive Consistency Segmentation (PCCS) for semi-supervised medical image segmentation. The core idea is to enforce the prototypes of the same semantic class to be closer and push the prototypes in different semantic classes far away from each other. Specifically, we construct a signed distance map and an uncertainty map from unlabeled images. The signed distance map is used to construct prototypes for contrastive learning, and then we estimate the prototype uncertainty from the uncertainty map as trade-off among prototypes. In order to obtain better prototypes, based on the student-teacher architecture, a new mechanism named prototype updating prototype is designed to assist in updating the prototypes for contrastive learning. In addition, we propose an uncertainty-consistency loss to mine more reliable information from unlabeled data. Extensive experiments on medical image segmentation demonstrate that PCCS achieves better segmentation performance than the state-of-the-art methods. The code is available at https://github.com/comphsh/PCCS.
2.0IVJul 12, 2019
Coupled-Projection Residual Network for MRI Super-ResolutionChun-Mei Feng, Kai Wang, Shijian Lu et al.
Magnetic Resonance Imaging(MRI) has been widely used in clinical application and pathology research by helping doctors make more accurate diagnoses. On the other hand, accurate diagnosis by MRI remains a great challenge as images obtained via present MRI techniques usually have low resolutions. Improving MRI image quality and resolution thus becomes a critically important task. This paper presents an innovative Coupled-Projection Residual Network (CPRN) for MRI super-resolution. The CPRN consists of two complementary sub-networks: a shallow network and a deep network that keep the content consistency while learning high frequency differences between low-resolution and high-resolution images. The shallow sub-network employs coupled-projection for better retaining the MRI image details, where a novel feedback mechanism is introduced to guide the reconstruction of high-resolution images. The deep sub-network learns from the residuals of the high-frequency image information, where multiple residual blocks are cascaded to magnify the MRI images at the last network layer. Finally, the features from the shallow and deep sub-networks are fused for the reconstruction of high-resolution MRI images. For effective fusion of features from the deep and shallow sub-networks, a step-wise connection (CPRN S) is designed as inspired by the human cognitive processes (from simple to complex). Experiments over three public MRI datasets show that our proposed CPRN achieves superior MRI super-resolution performance as compared with the state-of-the-art. Our source code will be publicly available at http://www.yongxu.org/lunwen.html.