MedSegDiff: Medical Image Segmentation with Diffusion Probabilistic ModelJunde Wu, Rao Fu, Huihui Fang et al.
Diffusion probabilistic model (DPM) recently becomes one of the hottest topic in computer vision. Its image generation application such as Imagen, Latent Diffusion Models and Stable Diffusion have shown impressive generation capabilities, which aroused extensive discussion in the community. Many recent studies also found it is useful in many other vision tasks, like image deblurring, super-resolution and anomaly detection. Inspired by the success of DPM, we propose the first DPM based model toward general medical image segmentation tasks, which we named MedSegDiff. In order to enhance the step-wise regional attention in DPM for the medical image segmentation, we propose dynamic conditional encoding, which establishes the state-adaptive conditions for each sampling step. We further propose Feature Frequency Parser (FF-Parser), to eliminate the negative effect of high-frequency noise component in this process. We verify MedSegDiff on three medical segmentation tasks with different image modalities, which are optic cup segmentation over fundus images, brain tumor segmentation over MRI images and thyroid nodule segmentation over ultrasound images. The experimental results show that MedSegDiff outperforms state-of-the-art (SOTA) methods with considerable performance gap, indicating the generalization and effectiveness of the proposed model. Our code is released at https://github.com/WuJunde/MedSegDiff.
2.6CVNov 29, 2022
ExpNet: A unified network for Expert-Level ClassificationJunde Wu, Huihui Fang, Yehui Yang et al.
Different from the general visual classification, some classification tasks are more challenging as they need the professional categories of the images. In the paper, we call them expert-level classification. Previous fine-grained vision classification (FGVC) has made many efforts on some of its specific sub-tasks. However, they are difficult to expand to the general cases which rely on the comprehensive analysis of part-global correlation and the hierarchical features interaction. In this paper, we propose Expert Network (ExpNet) to address the unique challenges of expert-level classification through a unified network. In ExpNet, we hierarchically decouple the part and context features and individually process them using a novel attentive mechanism, called Gaze-Shift. In each stage, Gaze-Shift produces a focal-part feature for the subsequent abstraction and memorizes a context-related embedding. Then we fuse the final focal embedding with all memorized context-related embedding to make the prediction. Such an architecture realizes the dual-track processing of partial and global information and hierarchical feature interactions. We conduct the experiments over three representative expert-level classification tasks: FGVC, disease classification, and artwork attributes classification. In these experiments, superior performance of our ExpNet is observed comparing to the state-of-the-arts in a wide range of fields, indicating the effectiveness and generalization of our ExpNet. The code will be made publicly available.
FCMBench-Video: Benchmarking Document Video IntelligenceRunze Cui, Fangxin Shang, Yehui Yang et al.
Document understanding is a critical capability in financial credit review, onboarding, and remote verification, where both decision accuracy and evidence traceability matter. Compared with static document images, document videos present a temporally redundant and sequentially unfolding evidence stream, require evidence integration across frames, and preserve acquisition-process cues relevant to authenticity-sensitive and anti-fraud review. We introduce FCMBench-Video, a benchmark for document-video intelligence that evaluates document perception, temporal grounding, and evidence-grounded reasoning under realistic capture conditions. For privacy-compliant yet realistic data at scale, we organize construction as an atomic-acquisition and composition workflow that records reusable single-document clips, applies controlled degradations, and assembles long-form multi-document videos with prescribed temporal spans. FCMBench-Video is built from 495 atomic videos composed into 1,200 long-form videos paired with 11,322 expert-annotated question--answer instances, covering 28 document types over 20s--60s duration tiers and 5,960 Chinese / 5,362 English instances. Evaluations on nine recent Video-MLLMs show that FCMBench-Video provides meaningful separation across systems and capabilities: counting is the most duration-sensitive task, Cross-Document Validation and Evidence-Grounded Selection probe higher-level evidence integration, and Visual Prompt Injection provides a complementary robustness dimension. The overall score distribution is broad and approximately bell-shaped, indicating a benchmark that is neither saturated nor dominated by trivial cases. Together, these results position FCMBench-Video as a reproducible benchmark for tracking Video-MLLM progress on document-video understanding and probing capability boundaries in authenticity-sensitive credit-domain applications.
1.4CVMay 31, 2022
Contrastive Centroid Supervision Alleviates Domain Shift in Medical Image ClassificationWenshuo Zhou, Dalu Yang, Binghong Wu et al.
Deep learning based medical imaging classification models usually suffer from the domain shift problem, where the classification performance drops when training data and real-world data differ in imaging equipment manufacturer, image acquisition protocol, patient populations, etc. We propose Feature Centroid Contrast Learning (FCCL), which can improve target domain classification performance by extra supervision during training with contrastive loss between instance and class centroid. Compared with current unsupervised domain adaptation and domain generalization methods, FCCL performs better while only requires labeled image data from a single source domain and no target domain. We verify through extensive experiments that FCCL can achieve superior performance on at least three imaging modalities, i.e. fundus photographs, dermatoscopic images, and H & E tissue images.
Towards a Multimodal Large Language Model with Pixel-Level Insight for BiomedicineXiaoshuang Huang, Lingdong Shen, Jia Liu et al.
In recent years, Multimodal Large Language Models (MLLM) have achieved notable advancements, demonstrating the feasibility of developing an intelligent biomedical assistant. However, current biomedical MLLMs predominantly focus on image-level understanding and restrict interactions to textual commands, thus limiting their capability boundaries and the flexibility of usage. In this paper, we introduce a novel end-to-end multimodal large language model for the biomedical domain, named MedPLIB, which possesses pixel-level understanding. Excitingly, it supports visual question answering (VQA), arbitrary pixel-level prompts (points, bounding boxes, and free-form shapes), and pixel-level grounding. We propose a novel Mixture-of-Experts (MoE) multi-stage training strategy, which divides MoE into separate training phases for a visual-language expert model and a pixel-grounding expert model, followed by fine-tuning using MoE. This strategy effectively coordinates multitask learning while maintaining the computational cost at inference equivalent to that of a single expert model. To advance the research of biomedical MLLMs, we introduce the Medical Complex Vision Question Answering Dataset (MeCoVQA), which comprises an array of 8 modalities for complex medical imaging question answering and image region understanding. Experimental results indicate that MedPLIB has achieved state-of-the-art outcomes across multiple medical visual language tasks. More importantly, in zero-shot evaluations for the pixel grounding task, MedPLIB leads the best small and large models by margins of 19.7 and 15.6 respectively on the mDice metric. The codes, data, and model checkpoints will be made publicly available at https://github.com/ShawnHuang497/MedPLIB.
5.2CVMar 18
Revisiting Cross-Attention Mechanisms: Leveraging Beneficial Noise for Domain-Adaptive LearningZelin Zang, Yehui Yang, Fei Wang et al.
Unsupervised Domain Adaptation (UDA) seeks to transfer knowledge from a labeled source domain to an unlabeled target domain but often suffers from severe domain and scale gaps that degrade performance. Existing cross-attention-based transformers can align features across domains, yet they struggle to preserve content semantics under large appearance and scale variations. To explicitly address these challenges, we introduce the concept of beneficial noise, which regularizes cross-attention by injecting controlled perturbations, encouraging the model to ignore style distractions and focus on content. We propose the Domain-Adaptive Cross-Scale Matching (DACSM) framework, which consists of a Domain-Adaptive Transformer (DAT) for disentangling domain-shared content from domain-specific style, and a Cross-Scale Matching (CSM) module that adaptively aligns features across multiple resolutions. DAT incorporates beneficial noise into cross-attention, enabling progressive domain translation with enhanced robustness, yielding content-consistent and style-invariant representations. Meanwhile, CSM ensures semantic consistency under scale changes. Extensive experiments on VisDA-2017, Office-Home, and DomainNet demonstrate that DACSM achieves state-of-the-art performance, with up to +2.3% improvement over CDTrans on VisDA-2017. Notably, DACSM achieves a +5.9% gain on the challenging "truck" class of VisDA, evidencing the strength of beneficial noise in handling scale discrepancies. These results highlight the effectiveness of combining domain translation, beneficial-noise-enhanced attention, and scale-aware alignment for robust cross-domain representation learning.
6.5CVMar 25, 2024Code
SegICL: A Multimodal In-context Learning Framework for Enhanced Segmentation in Medical ImagingLingdong Shen, Fangxin Shang, Xiaoshuang Huang et al.
In the field of medical image segmentation, tackling Out-of-Distribution (OOD) segmentation tasks in a cost-effective manner remains a significant challenge. Universal segmentation models is a solution, which aim to generalize across the diverse modality of medical images, yet their effectiveness often diminishes when applied to OOD data modalities and tasks, requiring intricate fine-tuning of model for optimal performance. Few-shot learning segmentation methods are typically designed for specific modalities of data and cannot be directly transferred for use with another modality. Therefore, we introduce SegICL, a novel approach leveraging In-Context Learning (ICL) for image segmentation. Unlike existing methods, SegICL has the capability to employ text-guided segmentation and conduct in-context learning with a small set of image-mask pairs, eliminating the need for training the model from scratch or fine-tuning for OOD tasks (including OOD modality and dataset). Extensive experimental demonstrates a positive correlation between the number of shots and segmentation performance on OOD tasks. The performance of segmentation when provided thre-shots is approximately 1.5 times better than the performance in a zero-shot setting. This indicates that SegICL effectively address new segmentation tasks based on contextual information. Additionally, SegICL also exhibits comparable performance to mainstream models on OOD and in-distribution tasks. Our code will be released after paper review.
3.7CVJan 30, 2024
An Embeddable Implicit IUVD Representation for Part-based 3D Human Surface ReconstructionBaoxing Li, Yong Deng, Yehui Yang et al.
To reconstruct a 3D human surface from a single image, it is crucial to simultaneously consider human pose, shape, and clothing details. Recent approaches have combined parametric body models (such as SMPL), which capture body pose and shape priors, with neural implicit functions that flexibly learn clothing details. However, this combined representation introduces additional computation, e.g. signed distance calculation in 3D body feature extraction, leading to redundancy in the implicit query-and-infer process and failing to preserve the underlying body shape prior. To address these issues, we propose a novel IUVD-Feedback representation, consisting of an IUVD occupancy function and a feedback query algorithm. This representation replaces the time-consuming signed distance calculation with a simple linear transformation in the IUVD space, leveraging the SMPL UV maps. Additionally, it reduces redundant query points through a feedback mechanism, leading to more reasonable 3D body features and more effective query points, thereby preserving the parametric body prior. Moreover, the IUVD-Feedback representation can be embedded into any existing implicit human reconstruction pipeline without requiring modifications to the trained neural networks. Experiments on the THuman2.0 dataset demonstrate that the proposed IUVD-Feedback representation improves the robustness of results and achieves three times faster acceleration in the query-and-infer process. Furthermore, this representation holds potential for generative applications by leveraging its inherent semantic information from the parametric body model.
A Refer-and-Ground Multimodal Large Language Model for BiomedicineXiaoshuang Huang, Haifeng Huang, Lingdong Shen et al.
With the rapid development of multimodal large language models (MLLMs), especially their capabilities in visual chat through refer and ground functionalities, their significance is increasingly recognized. However, the biomedical field currently exhibits a substantial gap in this area, primarily due to the absence of a dedicated refer and ground dataset for biomedical images. To address this challenge, we devised the Med-GRIT-270k dataset. It comprises 270k question-and-answer pairs and spans eight distinct medical imaging modalities. Most importantly, it is the first dedicated to the biomedical domain and integrating refer and ground conversations. The key idea is to sample large-scale biomedical image-mask pairs from medical segmentation datasets and generate instruction datasets from text using chatGPT. Additionally, we introduce a Refer-and-Ground Multimodal Large Language Model for Biomedicine (BiRD) by using this dataset and multi-task instruction learning. Extensive experiments have corroborated the efficacy of the Med-GRIT-270k dataset and the multi-modal, fine-grained interactive capabilities of the BiRD model. This holds significant reference value for the exploration and development of intelligent biomedical assistants.
Progressive Hard-case Mining across Pyramid Levels for Object DetectionBinghong Wu, Yehui Yang, Dalu Yang et al.
In object detection, multi-level prediction (e.g., FPN) and reweighting skills (e.g., focal loss) have drastically improved one-stage detector performance. However, the synergy between these two techniques is not fully explored in a unified framework. We find that, during training, the one-stage detector's optimization is not only restricted to the static hard-case mining loss (gradient drift) but also suffered from the diverse positive samples' proportions split by different pyramid levels (level discrepancy). Under this concern, we propose Hierarchical Progressive Focus (HPF) consisting of two key designs: 1) progressive focus, a more flexible hard-case mining setting calculated adaptive to the convergence progress, 2) hierarchical sampling, automatically generating a set of progressive focus for level-specific target optimization. Based on focal loss with ATSS-R50, our approach achieves 40.5 AP, surpassing the state-of-the-art QFL (Quality Focal Loss, 39.9 AP) and VFL (Varifocal Loss, 40.1 AP). Our best model achieves 55.1 AP on COCO test-dev, obtaining excellent results with only a typical training setting. Moreover, as a plug-and-play scheme, HPF can cooperate well with recent advances, providing a stable performance improvement on nine mainstream detectors.
4.2CVNov 27, 2020
Spherical Interpolated Convolutional Network with Distance-Feature Density for 3D Semantic Segmentation of Point CloudsGuangming Wang, Yehui Yang, Huixin Zhang et al.
The semantic segmentation of point clouds is an important part of the environment perception for robots. However, it is difficult to directly adopt the traditional 3D convolution kernel to extract features from raw 3D point clouds because of the unstructured property of point clouds. In this paper, a spherical interpolated convolution operator is proposed to replace the traditional grid-shaped 3D convolution operator. This newly proposed feature extraction operator improves the accuracy of the network and reduces the parameters of the network. In addition, this paper analyzes the defect of point cloud interpolation methods based on the distance as the interpolation weight and proposes the self-learned distance-feature density by combining the distance and the feature correlation. The proposed method makes the feature extraction of spherical interpolated convolution network more rational and effective. The effectiveness of the proposed network is demonstrated on the 3D semantic segmentation task of point clouds. Experiments show that the proposed method achieves good performance on the ScanNet dataset and Paris-Lille-3D dataset.