Rui Peng

Xuanlong Yu, Yi Zuo, Zitao Wang et al. · cmu

This paper outlines the winning solutions employed in addressing the MUAD uncertainty quantification challenge held at ICCV 2023. The challenge was centered around semantic segmentation in urban environments, with a particular focus on natural adversarial scenarios. The report presents the results of 19 submitted entries, with numerous techniques drawing inspiration from cutting-edge uncertainty quantification methodologies presented at prominent conferences in the fields of computer vision and machine learning and journals over the past few years. Within this document, the challenge is introduced, shedding light on its purpose and objectives, which primarily revolved around enhancing the robustness of semantic segmentation in urban scenes under varying natural adversarial conditions. The report then delves into the top-performing solutions. Moreover, the document aims to provide a comprehensive overview of the diverse solutions deployed by all participants. By doing so, it seeks to offer readers a deeper insight into the array of strategies that can be leveraged to effectively handle the inherent uncertainties associated with autonomous driving and semantic segmentation, especially within urban environments.

Anthony Cioppa, Silvio Giancola, Vladimir Somers et al. · pku

The SoccerNet 2023 challenges were the third annual video understanding challenges organized by the SoccerNet team. For this third edition, the challenges were composed of seven vision-based tasks split into three main themes. The first theme, broadcast video understanding, is composed of three high-level tasks related to describing events occurring in the video broadcasts: (1) action spotting, focusing on retrieving all timestamps related to global actions in soccer, (2) ball action spotting, focusing on retrieving all timestamps related to the soccer ball change of state, and (3) dense video captioning, focusing on describing the broadcast with natural language and anchored timestamps. The second theme, field understanding, relates to the single task of (4) camera calibration, focusing on retrieving the intrinsic and extrinsic camera parameters from images. The third and last theme, player understanding, is composed of three low-level tasks related to extracting information about the players: (5) re-identification, focusing on retrieving the same players across multiple views, (6) multiple object tracking, focusing on tracking players and the ball through unedited video streams, and (7) jersey number recognition, focusing on recognizing the jersey number of players from tracklets. Compared to the previous editions of the SoccerNet challenges, tasks (2-3-7) are novel, including new annotations and data, task (4) was enhanced with more data and annotations, and task (6) now focuses on end-to-end approaches. More information on the tasks, challenges, and leaderboards are available on https://www.soccer-net.org. Baselines and development kits can be found on https://github.com/SoccerNet.

Rui Peng, Shihe Shen, Kaiqiang Xiong et al.

Reconstructing the high-fidelity surface from multi-view images, especially sparse images, is a critical and practical task that has attracted widespread attention in recent years. However, existing methods are impeded by the memory constraint or the requirement of ground-truth depths and cannot recover satisfactory geometric details. To this end, we propose SuRF, a new Surface-centric framework that incorporates a new Region sparsification based on a matching Field, achieving good trade-offs between performance, efficiency and scalability. To our knowledge, this is the first unsupervised method achieving end-to-end sparsification powered by the introduced matching field, which leverages the weight distribution to efficiently locate the boundary regions containing surface. Instead of predicting an SDF value for each voxel, we present a new region sparsification approach to sparse the volume by judging whether the voxel is inside the surface region. In this way, our model can exploit higher frequency features around the surface with less memory and computational consumption. Extensive experiments on multiple benchmarks containing complex large-scale scenes show that our reconstructions exhibit high-quality details and achieve new state-of-the-art performance, i.e., 46% improvements with 80% less memory consumption. Code is available at https://github.com/prstrive/SuRF.

Jason Holmes, Rui Peng, Yiwei Li et al.

IMPORTANCE The response effectiveness of different large language models (LLMs) and various individuals, including medical students, graduate students, and practicing physicians, in pediatric ophthalmology consultations, has not been clearly established yet. OBJECTIVE Design a 100-question exam based on pediatric ophthalmology to evaluate the performance of LLMs in highly specialized scenarios and compare them with the performance of medical students and physicians at different levels. DESIGN, SETTING, AND PARTICIPANTS This survey study assessed three LLMs, namely ChatGPT (GPT-3.5), GPT-4, and PaLM2, were assessed alongside three human cohorts: medical students, postgraduate students, and attending physicians, in their ability to answer questions related to pediatric ophthalmology. It was conducted by administering questionnaires in the form of test papers through the LLM network interface, with the valuable participation of volunteers. MAIN OUTCOMES AND MEASURES Mean scores of LLM and humans on 100 multiple-choice questions, as well as the answer stability, correlation, and response confidence of each LLM. RESULTS GPT-4 performed comparably to attending physicians, while ChatGPT (GPT-3.5) and PaLM2 outperformed medical students but slightly trailed behind postgraduate students. Furthermore, GPT-4 exhibited greater stability and confidence when responding to inquiries compared to ChatGPT (GPT-3.5) and PaLM2. CONCLUSIONS AND RELEVANCE Our results underscore the potential for LLMs to provide medical assistance in pediatric ophthalmology and suggest significant capacity to guide the education of medical students.

Zhu Yu, Jingnan Gao, Runmin Zhang et al.

This work presents ViGeo, a feed-forward foundation model for recovering spatially dense and temporally consistent geometry from video sequences. Built upon a plain transformer architecture without task-specific architectural modifications, ViGeo supports streaming, full-sequence, and long-video inference within a unified model. The key design is dynamic chunking attention, which exposes the model to both bidirectional and causal temporal contexts during training and allows it to adapt its attention pattern at test time without retraining. To improve supervision quality, we further introduce a completion-based data refinement framework. This framework trains a video depth completion teacher that conditions on sparse and noisy annotations and exploits video/multi-view context to produce dense, temporally coherent, and geometrically reliable training targets. Beyond depth and point maps, ViGeo also predicts surface normals within the same framework. Trained solely on public datasets, ViGeo achieves state-of-the-art performance across online, offline, and long-video depth estimation, surface normal estimation, and video point map estimation.

Yongqi Zhai, Luyang Tang, Yi Ma et al.

With the wide application of stereo images in various fields, the research on stereo image compression (SIC) attracts extensive attention from academia and industry. The core of SIC is to fully explore the mutual information between the left and right images and reduce redundancy between views as much as possible. In this paper, we propose DispSIC, an end-to-end trainable deep neural network, in which we jointly train a stereo matching model to assist in the image compression task. Based on the stereo matching results (i.e. disparity), the right image can be easily warped to the left view, and only the residuals between the left and right views are encoded for the left image. A three-branch auto-encoder architecture is adopted in DispSIC, which encodes the right image, the disparity map and the residuals respectively. During training, the whole network can learn how to adaptively allocate bitrates to these three parts, achieving better rate-distortion performance at the cost of a lower disparity map bitrates. Moreover, we propose a conditional entropy model with aligned cross-view priors for SIC, which takes the warped latents of the right image as priors to improve the accuracy of the probability estimation for the left image. Experimental results demonstrate that our proposed method achieves superior performance compared to other existing SIC methods on the KITTI and InStereo2K datasets both quantitatively and qualitatively.

Haifeng Wang, Hua Wu, Tian Wu et al.

In this report, we introduce ERNIE 5.0, a natively autoregressive foundation model desinged for unified multimodal understanding and generation across text, image, video, and audio. All modalities are trained from scratch under a unified next-group-of-tokens prediction objective, based on an ultra-sparse mixture-of-experts (MoE) architecture with modality-agnostic expert routing. To address practical challenges in large-scale deployment under diverse resource constraints, ERNIE 5.0 adopts a novel elastic training paradigm. Within a single pre-training run, the model learns a family of sub-models with varying depths, expert capacities, and routing sparsity, enabling flexible trade-offs among performance, model size, and inference latency in memory- or time-constrained scenarios. Moreover, we systematically address the challenges of scaling reinforcement learning to unified foundation models, thereby guaranteeing efficient and stable post-training under ultra-sparse MoE architectures and diverse multimodal settings. Extensive experiments demonstrate that ERNIE 5.0 achieves strong and balanced performance across multiple modalities. To the best of our knowledge, among publicly disclosed models, ERNIE 5.0 represents the first production-scale realization of a trillion-parameter unified autoregressive model that supports both multimodal understanding and generation. To facilitate further research, we present detailed visualizations of modality-agnostic expert routing in the unified model, alongside comprehensive empirical analysis of elastic training, aiming to offer profound insights to the community.

Wangze Xu, Huachen Gao, Shihe Shen et al.

Recently, the Neural Radiance Field (NeRF) advancement has facilitated few-shot Novel View Synthesis (NVS), which is a significant challenge in 3D vision applications. Despite numerous attempts to reduce the dense input requirement in NeRF, it still suffers from time-consumed training and rendering processes. More recently, 3D Gaussian Splatting (3DGS) achieves real-time high-quality rendering with an explicit point-based representation. However, similar to NeRF, it tends to overfit the train views for lack of constraints. In this paper, we propose \textbf{MVPGS}, a few-shot NVS method that excavates the multi-view priors based on 3D Gaussian Splatting. We leverage the recent learning-based Multi-view Stereo (MVS) to enhance the quality of geometric initialization for 3DGS. To mitigate overfitting, we propose a forward-warping method for additional appearance constraints conforming to scenes based on the computed geometry. Furthermore, we introduce a view-consistent geometry constraint for Gaussian parameters to facilitate proper optimization convergence and utilize a monocular depth regularization as compensation. Experiments show that the proposed method achieves state-of-the-art performance with real-time rendering speed. Project page: https://zezeaaa.github.io/projects/MVPGS/

Jiahao Wu, Lu Xiao, Rui Peng et al.

Recent years have witnessed substantial advancements in the field of 3D reconstruction from 2D images, particularly following the introduction of the neural radiance field (NeRF) technique. However, reconstructing a 3D high dynamic range (HDR) radiance field, which aligns more closely with real-world conditions, from 2D multi-exposure low dynamic range (LDR) images continues to pose significant challenges. Approaches to this issue fall into two categories: grid-based and implicit-based. Implicit methods, using multi-layer perceptrons (MLP), face inefficiencies, limited solvability, and overfitting risks. Conversely, grid-based methods require significant memory and struggle with image quality and long training times. In this paper, we introduce Gaussian Splatting-a recent, high-quality, real-time 3D reconstruction technique-into this domain. We further develop the High Dynamic Range Gaussian Splatting (HDR-GS) method, designed to address the aforementioned challenges. This method enhances color dimensionality by including luminance and uses an asymmetric grid for tone-mapping, swiftly and precisely converting pixel irradiance to color. Our approach improves HDR scene recovery accuracy and integrates a novel coarse-to-fine strategy to speed up model convergence, enhancing robustness against sparse viewpoints and exposure extremes, and preventing local optima. Extensive testing confirms that our method surpasses current state-of-the-art techniques in both synthetic and real-world scenarios.

Rui Peng, Wangze Xu, Luyang Tang et al.

Despite the substantial progress of novel view synthesis, existing methods, either based on the Neural Radiance Fields (NeRF) or more recently 3D Gaussian Splatting (3DGS), suffer significant degradation when the input becomes sparse. Numerous efforts have been introduced to alleviate this problem, but they still struggle to synthesize satisfactory results efficiently, especially in the large scene. In this paper, we propose SCGaussian, a Structure Consistent Gaussian Splatting method using matching priors to learn 3D consistent scene structure. Considering the high interdependence of Gaussian attributes, we optimize the scene structure in two folds: rendering geometry and, more importantly, the position of Gaussian primitives, which is hard to be directly constrained in the vanilla 3DGS due to the non-structure property. To achieve this, we present a hybrid Gaussian representation. Besides the ordinary non-structure Gaussian primitives, our model also consists of ray-based Gaussian primitives that are bound to matching rays and whose optimization of their positions is restricted along the ray. Thus, we can utilize the matching correspondence to directly enforce the position of these Gaussian primitives to converge to the surface points where rays intersect. Extensive experiments on forward-facing, surrounding, and complex large scenes show the effectiveness of our approach with state-of-the-art performance and high efficiency. Code is available at https://github.com/prstrive/SCGaussian.

Shihe Shen, Huachen Gao, Wangze Xu et al.

The utilization of the triplane-based radiance fields has gained attention in recent years due to its ability to effectively disentangle 3D scenes with a high-quality representation and low computation cost. A key requirement of this method is the precise input of camera poses. However, due to the local update property of the triplane, a similar joint estimation as previous joint pose-NeRF optimization works easily results in local minima. To this end, we propose the Disentangled Triplane Generation module to introduce global feature context and smoothness into triplane learning, which mitigates errors caused by local updating. Then, we propose the Disentangled Plane Aggregation to mitigate the entanglement caused by the common triplane feature aggregation during camera pose updating. In addition, we introduce a two-stage warm-start training strategy to reduce the implicit constraints caused by the triplane generator. Quantitative and qualitative results demonstrate that our proposed method achieves state-of-the-art performance in novel view synthesis with noisy or unknown camera poses, as well as efficient convergence of optimization. Project page: https://gaohchen.github.io/DiGARR/.

Jiahao Wu, Rui Peng, Zhiyan Wang et al.

Novel view synthesis has long been a practical but challenging task, although the introduction of numerous methods to solve this problem, even combining advanced representations like 3D Gaussian Splatting, they still struggle to recover high-quality results and often consume too much storage memory and training time. In this paper we propose Swift4D, a divide-and-conquer 3D Gaussian Splatting method that can handle static and dynamic primitives separately, achieving a good trade-off between rendering quality and efficiency, motivated by the fact that most of the scene is the static primitive and does not require additional dynamic properties. Concretely, we focus on modeling dynamic transformations only for the dynamic primitives which benefits both efficiency and quality. We first employ a learnable decomposition strategy to separate the primitives, which relies on an additional parameter to classify primitives as static or dynamic. For the dynamic primitives, we employ a compact multi-resolution 4D Hash mapper to transform these primitives from canonical space into deformation space at each timestamp, and then mix the static and dynamic primitives to produce the final output. This divide-and-conquer method facilitates efficient training and reduces storage redundancy. Our method not only achieves state-of-the-art rendering quality while being 20X faster in training than previous SOTA methods with a minimum storage requirement of only 30MB on real-world datasets. Code is available at https://github.com/WuJH2001/swift4d.

Kaiqiang Xiong, Rui Peng, Jiahao Wu et al.

3D human reconstruction from a single image is a challenging problem and has been exclusively studied in the literature. Recently, some methods have resorted to diffusion models for guidance, optimizing a 3D representation via Score Distillation Sampling(SDS) or generating a back-view image for facilitating reconstruction. However, these methods tend to produce unsatisfactory artifacts (\textit{e.g.} flattened human structure or over-smoothing results caused by inconsistent priors from multiple views) and struggle with real-world generalization in the wild. In this work, we present \emph{MVD-HuGaS}, enabling free-view 3D human rendering from a single image via a multi-view human diffusion model. We first generate multi-view images from the single reference image with an enhanced multi-view diffusion model, which is well fine-tuned on high-quality 3D human datasets to incorporate 3D geometry priors and human structure priors. To infer accurate camera poses from the sparse generated multi-view images for reconstruction, an alignment module is introduced to facilitate joint optimization of 3D Gaussians and camera poses. Furthermore, we propose a depth-based Facial Distortion Mitigation module to refine the generated facial regions, thereby improving the overall fidelity of the reconstruction. Finally, leveraging the refined multi-view images, along with their accurate camera poses, MVD-HuGaS optimizes the 3D Gaussians of the target human for high-fidelity free-view renderings. Extensive experiments on Thuman2.0 and 2K2K datasets show that the proposed MVD-HuGaS achieves state-of-the-art performance on single-view 3D human rendering.

Rui Peng, Xiaodong Gu, Luyang Tang et al.

Combining the signed distance function (SDF) and differentiable volume rendering has emerged as a powerful paradigm for surface reconstruction from multi-view images without 3D supervision. However, current methods are impeded by requiring long-time per-scene optimizations and cannot generalize to new scenes. In this paper, we present GenS, an end-to-end generalizable neural surface reconstruction model. Unlike coordinate-based methods that train a separate network for each scene, we construct a generalized multi-scale volume to directly encode all scenes. Compared with existing solutions, our representation is more powerful, which can recover high-frequency details while maintaining global smoothness. Meanwhile, we introduce a multi-scale feature-metric consistency to impose the multi-view consistency in a more discriminative multi-scale feature space, which is robust to the failures of the photometric consistency. And the learnable feature can be self-enhanced to continuously improve the matching accuracy and mitigate aggregation ambiguity. Furthermore, we design a view contrast loss to force the model to be robust to those regions covered by few viewpoints through distilling the geometric prior from dense input to sparse input. Extensive experiments on popular benchmarks show that our model can generalize well to new scenes and outperform existing state-of-the-art methods even those employing ground-truth depth supervision. Code is available at https://github.com/prstrive/GenS.

Qi Zuo, Xiaodong Gu, Lingteng Qiu et al.

Generating multi-view images based on text or single-image prompts is a critical capability for the creation of 3D content. Two fundamental questions on this topic are what data we use for training and how to ensure multi-view consistency. This paper introduces a novel framework that makes fundamental contributions to both questions. Unlike leveraging images from 2D diffusion models for training, we propose a dense consistent multi-view generation model that is fine-tuned from off-the-shelf video generative models. Images from video generative models are more suitable for multi-view generation because the underlying network architecture that generates them employs a temporal module to enforce frame consistency. Moreover, the video data sets used to train these models are abundant and diverse, leading to a reduced train-finetuning domain gap. To enhance multi-view consistency, we introduce a 3D-Aware Denoising Sampling, which first employs a feed-forward reconstruction module to get an explicit global 3D model, and then adopts a sampling strategy that effectively involves images rendered from the global 3D model into the denoising sampling loop to improve the multi-view consistency of the final images. As a by-product, this module also provides a fast way to create 3D assets represented by 3D Gaussians within a few seconds. Our approach can generate 24 dense views and converges much faster in training than state-of-the-art approaches (4 GPU hours versus many thousand GPU hours) with comparable visual quality and consistency. By further fine-tuning, our approach outperforms existing state-of-the-art methods in both quantitative metrics and visual effects. Our project page is aigc3d.github.io/VideoMV.

Jinbo Yan, Rui Peng, Luyang Tang et al.

Reconstructing dynamic scenes from video sequences is a highly promising task in the multimedia domain. While previous methods have made progress, they often struggle with slow rendering and managing temporal complexities such as significant motion and object appearance/disappearance. In this paper, we propose SaRO-GS as a novel dynamic scene representation capable of achieving real-time rendering while effectively handling temporal complexities in dynamic scenes. To address the issue of slow rendering speed, we adopt a Gaussian primitive-based representation and optimize the Gaussians in 4D space, which facilitates real-time rendering with the assistance of 3D Gaussian Splatting. Additionally, to handle temporally complex dynamic scenes, we introduce a Scale-aware Residual Field. This field considers the size information of each Gaussian primitive while encoding its residual feature and aligns with the self-splitting behavior of Gaussian primitives. Furthermore, we propose an Adaptive Optimization Schedule, which assigns different optimization strategies to Gaussian primitives based on their distinct temporal properties, thereby expediting the reconstruction of dynamic regions. Through evaluations on monocular and multi-view datasets, our method has demonstrated state-of-the-art performance. Please see our project page at https://yjb6.github.io/SaRO-GS.github.io.

Kaiqiang Xiong, Rui Peng, Zhe Zhang et al.

Unsupervised Multi-View Stereo (MVS) methods have achieved promising progress recently. However, previous methods primarily depend on the photometric consistency assumption, which may suffer from two limitations: indistinguishable regions and view-dependent effects, e.g., low-textured areas and reflections. To address these issues, in this paper, we propose a new dual-level contrastive learning approach, named CL-MVSNet. Specifically, our model integrates two contrastive branches into an unsupervised MVS framework to construct additional supervisory signals. On the one hand, we present an image-level contrastive branch to guide the model to acquire more context awareness, thus leading to more complete depth estimation in indistinguishable regions. On the other hand, we exploit a scene-level contrastive branch to boost the representation ability, improving robustness to view-dependent effects. Moreover, to recover more accurate 3D geometry, we introduce an L0.5 photometric consistency loss, which encourages the model to focus more on accurate points while mitigating the gradient penalty of undesirable ones. Extensive experiments on DTU and Tanks&Temples benchmarks demonstrate that our approach achieves state-of-the-art performance among all end-to-end unsupervised MVS frameworks and outperforms its supervised counterpart by a considerable margin without fine-tuning.

Jinbo Yan, Rui Peng, Zhiyan Wang et al.

Building Free-Viewpoint Videos in a streaming manner offers the advantage of rapid responsiveness compared to offline training methods, greatly enhancing user experience. However, current streaming approaches face challenges of high per-frame reconstruction time (10s+) and error accumulation, limiting their broader application. In this paper, we propose Instant Gaussian Stream (IGS), a fast and generalizable streaming framework, to address these issues. First, we introduce a generalized Anchor-driven Gaussian Motion Network, which projects multi-view 2D motion features into 3D space, using anchor points to drive the motion of all Gaussians. This generalized Network generates the motion of Gaussians for each target frame in the time required for a single inference. Second, we propose a Key-frame-guided Streaming Strategy that refines each key frame, enabling accurate reconstruction of temporally complex scenes while mitigating error accumulation. We conducted extensive in-domain and cross-domain evaluations, demonstrating that our approach can achieve streaming with a average per-frame reconstruction time of 2s+, alongside a enhancement in view synthesis quality.

Rui Peng, Ziru Liu, Lingyuan Ye et al.

Accurately modeling the relationship between perturbations, transcriptional responses, and phenotypic changes is essential for building an AI Virtual Cell (AIVC). However, existing methods typically constrained to modeling direct associations, such as Perturbation $\rightarrow$ RNA or Perturbation $\rightarrow$ Morphology, overlook the crucial causal link from RNA to morphology. To bridge this gap, we propose TRIDENT, a cascade generative framework that synthesizes realistic cellular morphology by conditioning on both the perturbation and the corresponding gene expression profile. To train and evaluate this task, we construct MorphoGene, a new dataset pairing L1000 gene expression with Cell Painting images for 98 compounds. TRIDENT significantly outperforms state-of-the-art approaches, achieving up to 7-fold improvement with strong generalization to unseen compounds. In a case study on docetaxel, we validate that RNA-guided synthesis accurately produces the corresponding phenotype. An ablation study further confirms that this RNA conditioning is essential for the model's high fidelity. By explicitly modeling transcriptome-phenome mapping, TRIDENT provides a powerful in silico tool and moves us closer to a predictive virtual cell.

Yuxing Lu, Xukai Zhao, J. Ben Tamo et al. · pku

Large Language Models (LLMs) have demonstrated remarkable capabilities on general text; however, their proficiency in specialized scientific domains that require deep, interconnected knowledge remains largely uncharacterized. Metabolomics presents unique challenges with its complex biochemical pathways, heterogeneous identifier systems, and fragmented databases. To systematically evaluate LLM capabilities in this domain, we introduce MetaBench, the first benchmark for metabolomics assessment. Curated from authoritative public resources, MetaBench evaluates five capabilities essential for metabolomics research: knowledge, understanding, grounding, reasoning, and research. Our evaluation of 25 open- and closed-source LLMs reveals distinct performance patterns across metabolomics tasks: while models perform well on text generation tasks, cross-database identifier grounding remains challenging even with retrieval augmentation. Model performance also decreases on long-tail metabolites with sparse annotations. With MetaBench, we provide essential infrastructure for developing and evaluating metabolomics AI systems, enabling systematic progress toward reliable computational tools for metabolomics research.

Jiahao Wu, Rui Peng, Jianbo Jiao et al.

Due to the complex and highly dynamic motions in the real world, synthesizing dynamic videos from multi-view inputs for arbitrary viewpoints is challenging. Previous works based on neural radiance field or 3D Gaussian splatting are limited to modeling fine-scale motion, greatly restricting their application. In this paper, we introduce LocalDyGS, which consists of two parts to adapt our method to both large-scale and fine-scale motion scenes: 1) We decompose a complex dynamic scene into streamlined local spaces defined by seeds, enabling global modeling by capturing motion within each local space. 2) We decouple static and dynamic features for local space motion modeling. A static feature shared across time steps captures static information, while a dynamic residual field provides time-specific features. These are combined and decoded to generate Temporal Gaussians, modeling motion within each local space. As a result, we propose a novel dynamic scene reconstruction framework to model highly dynamic real-world scenes more realistically. Our method not only demonstrates competitive performance on various fine-scale datasets compared to state-of-the-art (SOTA) methods, but also represents the first attempt to model larger and more complex highly dynamic scenes. Project page: https://wujh2001.github.io/LocalDyGS/.

Xuejun Sun, Yiran Song, Xiaochen Zhou et al.

Respiratory viral infections pose a global health burden, yet the cellular immune responses driving protection or pathology remain unclear. Natural infection cohorts often lack pre-exposure baseline data and structured temporal sampling. In contrast, inoculation and vaccination trials generate insightful longitudinal transcriptomic data. However, the scattering of these datasets across platforms, along with inconsistent metadata and preprocessing procedure, hinders AI-driven discovery. To address these challenges, we developed the Human Respiratory Viral Immunization LongitudinAl Gene Expression (HR-VILAGE-3K3M) repository: an AI-ready, rigorously curated dataset that integrates 14,136 RNA-seq profiles from 3,178 subjects across 66 studies encompassing over 2.56 million cells. Spanning vaccination, inoculation, and mixed exposures, the dataset includes microarray, bulk RNA-seq, and single-cell RNA-seq from whole blood, PBMCs, and nasal swabs, sourced from GEO, ImmPort, and ArrayExpress. We harmonized subject-level metadata, standardized outcome measures, applied unified preprocessing pipelines with rigorous quality control, and aligned all data to official gene symbols. To demonstrate the utility of HR-VILAGE-3K3M, we performed predictive modeling of vaccine responders and evaluated batch-effect correction methods. Beyond these initial demonstrations, it supports diverse systems immunology applications and benchmarking of feature selection and transfer learning algorithms. Its scale and heterogeneity also make it ideal for pretraining foundation models of the human immune response and for advancing multimodal learning frameworks. As the largest longitudinal transcriptomic resource for human respiratory viral immunization, it provides an accessible platform for reproducible AI-driven research, accelerating systems immunology and vaccine development against emerging viral threats.

Qichen Sun, Zhengrui Guo, Rui Peng et al.

Recent advances in computational pathology and artificial intelligence have significantly enhanced the utilization of gigapixel whole-slide images and and additional modalities (e.g., genomics) for pathological diagnosis. Although deep learning has demonstrated strong potential in pathology, several key challenges persist: (1) fusing heterogeneous data types requires sophisticated strategies beyond simple concatenation due to high computational costs; (2) common scenarios of missing modalities necessitate flexible strategies that allow the model to learn robustly in the absence of certain modalities; (3) the downstream tasks in CPath are diverse, ranging from unimodal to multimodal, cnecessitating a unified model capable of handling all modalities. To address these challenges, we propose ALTER, an any-to-any tri-modal pretraining framework that integrates WSIs, genomics, and pathology reports. The term "any" emphasizes ALTER's modality-adaptive design, enabling flexible pretraining with any subset of modalities, and its capacity to learn robust, cross-modal representations beyond WSI-centric approaches. We evaluate ALTER across extensive clinical tasks including survival prediction, cancer subtyping, gene mutation prediction, and report generation, achieving superior or comparable performance to state-of-the-art baselines.

Rui Peng, Rongjie Wang, Zhenyu Wang et al.

Depth estimation is solved as a regression or classification problem in existing learning-based multi-view stereo methods. Although these two representations have recently demonstrated their excellent performance, they still have apparent shortcomings, e.g., regression methods tend to overfit due to the indirect learning cost volume, and classification methods cannot directly infer the exact depth due to its discrete prediction. In this paper, we propose a novel representation, termed Unification, to unify the advantages of regression and classification. It can directly constrain the cost volume like classification methods, but also realize the sub-pixel depth prediction like regression methods. To excavate the potential of unification, we design a new loss function named Unified Focal Loss, which is more uniform and reasonable to combat the challenge of sample imbalance. Combining these two unburdened modules, we present a coarse-to-fine framework, that we call UniMVSNet. The results of ranking first on both DTU and Tanks and Temples benchmarks verify that our model not only performs the best but also has the best generalization ability.

Rui Peng, Zehao Wang, Peng Lu

Aerial robotic systems have raised emerging interests in recent years. In this article, we propose a novel aerial manipulator system that is significantly different from conventional aerial discrete manipulators: An Aerial Continuum Manipulator (AeCoM). The AeCoM compactly integrates a quadrotor with a tendon-driven continuum robotic manipulator. Due to the compact design and the payload bearing ability of tendon-driven continuum robotic arms, the proposed system solved the conflict between payload capacity and dexterity lying in conventional aerial manipulators. Two contributions are made in this paper: 1) a sensor-based kinematic model is developed for precise modeling in the presence of variable loading; and 2) a tendon slacking prevention system is developed in the presence of aggressive motions. The detailed design of the system is presented and extensive experimental validations have been performed to validate the system self-initialization, payload capacity, precise kinematic modeling with variable end-effector (EE) loadings during aerial grasping and tendon-slacking prevention. The experimental results demonstrate that the proposed novel aerial continuum manipulator system solves the constraints in conventional aerial manipulators and has more potential applications in clustered environments.

Rui Peng, Ronggang Wang, Yawen Lai et al.

Self-supervised methods play an increasingly important role in monocular depth estimation due to their great potential and low annotation cost. To close the gap with supervised methods, recent works take advantage of extra constraints, e.g., semantic segmentation. However, these methods will inevitably increase the burden on the model. In this paper, we show theoretical and empirical evidence that the potential capacity of self-supervised monocular depth estimation can be excavated without increasing this cost. In particular, we propose (1) a novel data augmentation approach called data grafting, which forces the model to explore more cues to infer depth besides the vertical image position, (2) an exploratory self-distillation loss, which is supervised by the self-distillation label generated by our new post-processing method - selective post-processing, and (3) the full-scale network, designed to endow the encoder with the specialization of depth estimation task and enhance the representational power of the model. Extensive experiments show that our contributions can bring significant performance improvement to the baseline with even less computational overhead, and our model, named EPCDepth, surpasses the previous state-of-the-art methods even those supervised by additional constraints.

Peng Zhou, Rui Peng, Maggie Xu et al.

This paper presents a point cloud based robotic system for arc welding. Using hand gesture controls, the system scans partial point cloud views of workpiece and reconstructs them into a complete 3D model by a linear iterative closest point algorithm. Then, a bilateral filter is extended to denoise the workpiece model and preserve important geometrical information. To extract the welding seam from the model, a novel intensity-based algorithm is proposed that detects edge points and generates a smooth 6-DOF welding path. The methods are tested on multiple workpieces with different joint types and poses. Experimental results prove the robustness and efficiency of this robotic system on automatic path planning for welding applications.

Rui Peng, David Navarro-Alarcon, Victor Wu et al.

In this paper, in order to pursue high-efficiency robotic arc welding tasks, we propose a method based on point cloud acquired by an RGB-D sensor. The method consists of two parts: welding groove detection and 3D welding trajectory generation. The actual welding scene could be displayed in 3D point cloud format. Focusing on the geometric feature of the welding groove, the detection algorithm is capable of adapting well to different welding workpieces with a V-type welding groove. Meanwhile, a 3D welding trajectory involving 6-DOF poses of the welding groove for robotic manipulator motion is generated. With an acceptable error in trajectory generation, the robotic manipulator could drive the welding torch to follow the trajectory and execute welding tasks. In this paper, details of the integrated robotic system are also presented. Experimental results prove application value of the presented welding robotic system.

Hengyuan Hu, Rui Peng, Yu-Wing Tai et al.

State-of-the-art neural networks are getting deeper and wider. While their performance increases with the increasing number of layers and neurons, it is crucial to design an efficient deep architecture in order to reduce computational and memory costs. Designing an efficient neural network, however, is labor intensive requiring many experiments, and fine-tunings. In this paper, we introduce network trimming which iteratively optimizes the network by pruning unimportant neurons based on analysis of their outputs on a large dataset. Our algorithm is inspired by an observation that the outputs of a significant portion of neurons in a large network are mostly zero, regardless of what inputs the network received. These zero activation neurons are redundant, and can be removed without affecting the overall accuracy of the network. After pruning the zero activation neurons, we retrain the network using the weights before pruning as initialization. We alternate the pruning and retraining to further reduce zero activations in a network. Our experiments on the LeNet and VGG-16 show that we can achieve high compression ratio of parameters without losing or even achieving higher accuracy than the original network.