Wen Tang

Pengxin Yu, Haoyue Zhang, Han Kang et al.

In clinical practice, anisotropic volumetric medical images with low through-plane resolution are commonly used due to short acquisition time and lower storage cost. Nevertheless, the coarse resolution may lead to difficulties in medical diagnosis by either physicians or computer-aided diagnosis algorithms. Deep learning-based volumetric super-resolution (SR) methods are feasible ways to improve resolution, with convolutional neural networks (CNN) at their core. Despite recent progress, these methods are limited by inherent properties of convolution operators, which ignore content relevance and cannot effectively model long-range dependencies. In addition, most of the existing methods use pseudo-paired volumes for training and evaluation, where pseudo low-resolution (LR) volumes are generated by a simple degradation of their high-resolution (HR) counterparts. However, the domain gap between pseudo- and real-LR volumes leads to the poor performance of these methods in practice. In this paper, we build the first public real-paired dataset RPLHR-CT as a benchmark for volumetric SR, and provide baseline results by re-implementing four state-of-the-art CNN-based methods. Considering the inherent shortcoming of CNN, we also propose a transformer volumetric super-resolution network (TVSRN) based on attention mechanisms, dispensing with convolutions entirely. This is the first research to use a pure transformer for CT volumetric SR. The experimental results show that TVSRN significantly outperforms all baselines on both PSNR and SSIM. Moreover, the TVSRN method achieves a better trade-off between the image quality, the number of parameters, and the running time. Data and code are available at https://github.com/smilenaxx/RPLHR-CT.

Long Chen, Wen Tang, Nigel John et al.

Mixed Reality (MR) is a powerful interactive technology that yields new types of user experience. We present a semantic based interactive MR framework that exceeds the current geometry level approaches, a step change in generating high-level context-aware interactions. Our key insight is to build semantic understanding in MR that not only can greatly enhance user experience through object-specific behaviours, but also pave the way for solving complex interaction design challenges. The framework generates semantic properties of the real world environment through dense scene reconstruction and deep image understanding. We demonstrate our approach with a material-aware prototype system for generating context-aware physical interactions between the real and the virtual objects. Quantitative and qualitative evaluations are carried out and the results show that the framework delivers accurate and fast semantic information in interactive MR environment, providing effective semantic level interactions.

Long Chen, Wen Tang, Nigel John

Convolutional Neural Networks (CNNs) need large amounts of data with ground truth annotation, which is a challenging problem that has limited the development and fast deployment of CNNs for many computer vision tasks. We propose a novel framework for depth estimation from monocular images with corresponding confidence in a self-supervised manner. A fully differential patch-based cost function is proposed by using the Zero-Mean Normalized Cross Correlation (ZNCC) that takes multi-scale patches as a matching strategy. This approach greatly increases the accuracy and robustness of the depth learning. In addition, the proposed patch-based cost function can provide a 0 to 1 confidence, which is then used to supervise the training of a parallel network for confidence map learning and estimation. Evaluation on KITTI dataset shows that our method outperforms the state-of-the-art results.

Long Chen, Wen Tang, Nigel W. John

The potential of Augmented Reality (AR) technology to assist minimally invasive surgeries (MIS) lies in its computational performance and accuracy in dealing with challenging MIS scenes. Even with the latest hardware and software technologies, achieving both real-time and accurate augmented information overlay in MIS is still a formidable task. In this paper, we present a novel real-time AR framework for MIS that achieves interactive geometric aware augmented reality in endoscopic surgery with stereo views. Our framework tracks the movement of the endoscopic camera and simultaneously reconstructs a dense geometric mesh of the MIS scene. The movement of the camera is predicted by minimising the re-projection error to achieve a fast tracking performance, while the 3D mesh is incrementally built by a dense zero mean normalised cross correlation stereo matching method to improve the accuracy of the surface reconstruction. Our proposed system does not require any prior template or pre-operative scan and can infer the geometric information intra-operatively in real-time. With the geometric information available, our proposed AR framework is able to interactively add annotations, localisation of tumours and vessels, and measurement labelling with greater precision and accuracy compared with the state of the art approaches.

Long Chen, Thomas Day, Wen Tang et al.

Mixed Reality (MR) is of increasing interest within technology-driven modern medicine but is not yet used in everyday practice. This situation is changing rapidly, however, and this paper explores the emergence of MR technology and the importance of its utility within medical applications. A classification of medical MR has been obtained by applying an unbiased text mining method to a database of 1,403 relevant research papers published over the last two decades. The classification results reveal a taxonomy for the development of medical MR research during this period as well as suggesting future trends. We then use the classification to analyse the technology and applications developed in the last five years. Our objective is to aid researchers to focus on the areas where technology advancements in medical MR are most needed, as well as providing medical practitioners with a useful source of reference.

Long Chen, Karl Francis, Wen Tang

In Augmented Reality (AR) environment, realistic interactions between the virtual and real objects play a crucial role in user experience. Much of recent advances in AR has been largely focused on developing geometry-aware environment, but little has been done in dealing with interactions at the semantic level. High-level scene understanding and semantic descriptions in AR would allow effective design of complex applications and enhanced user experience. In this paper, we present a novel approach and a prototype system that enables the deeper understanding of semantic properties of the real world environment, so that realistic physical interactions between the real and the virtual objects can be generated. A material-aware AR environment has been created based on the deep material learning using a fully convolutional network (FCN). The state-of-the-art dense Simultaneous Localisation and Mapping (SLAM) has been used for the semantic mapping. Together with efficient accelerated 3D ray casting, natural and realistic physical interactions are generated for interactive AR games. Our approach has significant impact on the future development of advanced AR systems and applications.

Long Chen, Wen Tang, Nigel W. John et al.

One of the major challenges in Minimally Invasive Surgery (MIS) such as laparoscopy is the lack of depth perception. In recent years, laparoscopic scene tracking and surface reconstruction has been a focus of investigation to provide rich additional information to aid the surgical process and compensate for the depth perception issue. However, robust 3D surface reconstruction and augmented reality with depth perception on the reconstructed scene are yet to be reported. This paper presents our work in this area. First, we adopt a state-of-the-art visual simultaneous localization and mapping (SLAM) framework - ORB-SLAM - and extend the algorithm for use in MIS scenes for reliable endoscopic camera tracking and salient point mapping. We then develop a robust global 3D surface reconstruction frame- work based on the sparse point clouds extracted from the SLAM framework. Our approach is to combine an outlier removal filter within a Moving Least Squares smoothing algorithm and then employ Poisson surface reconstruction to obtain smooth surfaces from the unstructured sparse point cloud. Our proposed method has been quantitatively evaluated compared with ground-truth camera trajectories and the organ model surface we used to render the synthetic simulation videos. In vivo laparoscopic videos used in the tests have demonstrated the robustness and accuracy of our proposed framework on both camera tracking and surface reconstruction, illustrating the potential of our algorithm for depth augmentation and depth-corrected augmented reality in MIS with monocular endoscopes.