Hao Chen

Muzhi Zhu, Yuzhuo Tian, Hao Chen et al.

While MLLMs have demonstrated adequate image understanding capabilities, they still struggle with pixel-level comprehension, limiting their practical applications. Current evaluation tasks like VQA and visual grounding remain too coarse to assess fine-grained pixel comprehension accurately. Though segmentation is foundational for pixel-level understanding, existing methods often require MLLMs to generate implicit tokens, decoded through external pixel decoders. This approach disrupts the MLLM's text output space, potentially compromising language capabilities and reducing flexibility and extensibility, while failing to reflect the model's intrinsic pixel-level understanding. Thus, we introduce the Human-Like Mask Annotation Task (HLMAT), a new paradigm where MLLMs mimic human annotators using interactive segmentation tools. Modeling segmentation as a multi-step Markov Decision Process, HLMAT enables MLLMs to iteratively generate text-based click points, achieving high-quality masks without architectural changes or implicit tokens. Through this setup, we develop SegAgent, a model fine-tuned on human-like annotation trajectories, which achieves performance comparable to state-of-the-art (SOTA) methods and supports additional tasks like mask refinement and annotation filtering. HLMAT provides a protocol for assessing fine-grained pixel understanding in MLLMs and introduces a vision-centric, multi-step decision-making task that facilitates exploration of MLLMs' visual reasoning abilities. Our adaptations of policy improvement method StaR and PRM-guided tree search further enhance model robustness in complex segmentation tasks, laying a foundation for future advancements in fine-grained visual perception and multi-step decision-making for MLLMs.

Zheng Huang, Mingyu Liu, Xiaoyi Lin et al.

Vision-Language-Action (VLA) models represent a pivotal advance in embodied intelligence, yet they confront critical barriers to real-world deployment, most notably catastrophic forgetting. This issue stems from their overreliance on continuous action sequences or action chunks, which inadvertently create isolated data silos that disrupt knowledge retention across tasks. To tackle these challenges, we propose the Narrowing of Trajectory VLA (NoTVLA) framework: a novel approach that narrows its focus to sparse trajectories, thereby avoiding the catastrophic forgetting associated with dense trajectory fine-tuning. A key innovation of NoTVLA lies in its trajectory planning strategy: instead of centering on the target object's trajectory, it leverages temporal compression and spatial reasoning pruning specifically for the robot end effector's trajectory. Furthermore, training is conducted using these sparse trajectories rather than dense action trajectories, an optimization that delivers remarkable practical advantages with better performance in zero-shot. In multi-task evaluation scenarios, NoTVLA achieves superior performance and generalization compared to pi0 while operating under two critical constraints: it uses over an order of magnitude less computing power than pi0 and requires no wrist-mounted camera. This design ensures that NoTVLA's operational accuracy closely approximates that of single-task expert models. Crucially, it also preserves the model's inherent language capabilities, enabling zero-shot generalization in specific scenarios, supporting unified model deployment across multiple robot platforms, and fostering a degree of generalization even when perceiving tasks from novel perspectives.

Huajun Zhou, Fengtao Zhou, Jiabo Ma et al.

Multimodal data provides heterogeneous information for a holistic understanding of the tumor microenvironment. However, existing AI models often struggle to harness the rich information within multimodal data and extract poorly generalizable representations. Here we present MICE (Multimodal data Integration via Collaborative Experts), a multimodal foundation model that effectively integrates pathology images, clinical reports, and genomics data for precise pan-cancer prognosis prediction. Instead of conventional multi-expert modules, MICE employs multiple functionally diverse experts to comprehensively capture both cross-cancer and cancer-specific insights. Leveraging data from 11,799 patients across 30 cancer types, we enhanced MICE's generalizability by coupling contrastive and supervised learning. MICE outperformed both unimodal and state-of-the-art multi-expert-based multimodal models, demonstrating substantial improvements in C-index ranging from 3.8% to 11.2% on internal cohorts and 5.8% to 8.8% on independent cohorts, respectively. Moreover, it exhibited remarkable data efficiency across diverse clinical scenarios. With its enhanced generalizability and data efficiency, MICE establishes an effective and scalable foundation for pan-cancer prognosis prediction, holding strong potential to personalize tailored therapies and improve treatment outcomes.