Wen Wang

Wen Wang, Jianzong Wang, Shijing Si et al.

The extraction of sequence patterns from a collection of functionally linked unlabeled DNA sequences is known as DNA motif discovery, and it is a key task in computational biology. Several deep learning-based techniques have recently been introduced to address this issue. However, these algorithms can not be used in real-world situations because of the need for labeled data. Here, we presented RL-MD, a novel reinforcement learning based approach for DNA motif discovery task. RL-MD takes unlabelled data as input, employs a relative information-based method to evaluate each proposed motif, and utilizes these continuous evaluation results as the reward. The experiments show that RL-MD can identify high-quality motifs in real-world data.

Liyang Li, Wen Wang, Canyu Zhao et al.

Recent advances in Diffusion Transformers (DiTs) have enabled high-quality joint audio-video generation, producing videos with synchronized audio within a single model. However, existing controllable generation frameworks are typically restricted to video-only control. This restricts comprehensive controllability and often leads to suboptimal cross-modal alignment. To bridge this gap, we present MMControl, which enables users to perform Multi-Modal Control in joint audio-video generation. MMControl introduces a dual-stream conditional injection mechanism. It incorporates both visual and acoustic control signals, including reference images, reference audio, depth maps, and pose sequences, into a joint generation process. These conditions are injected through bypass branches into a joint audio-video Diffusion Transformer, enabling the model to simultaneously generate identity-consistent video and timbre-consistent audio under structural constraints. Furthermore, we introduce modality-specific guidance scaling, which allows users to independently and dynamically adjust the influence strength of each visual and acoustic condition at inference time. Extensive experiments demonstrate that MMControl achieves fine-grained, composable control over character identity, voice timbre, body pose, and scene layout in joint audio-video generation.