An Zhao

Wing Keung Cheung, Ashkan Pakzad, Nesrin Mogulkoc et al.

The morphology and distribution of airway tree abnormalities enables diagnosis and disease characterisation across a variety of chronic respiratory conditions. In this regard, airway segmentation plays a critical role in the production of the outline of the entire airway tree to enable estimation of disease extent and severity. In this study, we propose a data-centric deep learning technique to segment the airway tree. The proposed technique utilises interpolation and image split to improve data usefulness and quality. Then, an ensemble learning strategy is implemented to aggregate the segmented airway trees at different scales. In terms of segmentation performance (dice similarity coefficient), our method outperforms the baseline model by 2.5% on average when a combined loss is used. Further, our proposed technique has a low GPU usage and high flexibility enabling it to be deployed on any 2D deep learning model.

Shengyuan Zhang, An Zhao, Ling Yang et al.

Diffusion models have been applied to 3D LiDAR scene completion due to their strong training stability and high completion quality. However, the slow sampling speed limits the practical application of diffusion-based scene completion models since autonomous vehicles require an efficient perception of surrounding environments. This paper proposes a novel distillation method tailored for 3D Li- DAR scene completion models, dubbed ScoreLiDAR, which achieves efficient yet high-quality scene completion. Score- LiDAR enables the distilled model to sample in significantly fewer steps after distillation. To improve completion quality, we also introduce a novel Structural Loss, which encourages the distilled model to capture the geometric structure of the 3D LiDAR scene. The loss contains a scene-wise term constraining the holistic structure and a point-wise term constraining the key landmark points and their relative configuration. Extensive experiments demonstrate that ScoreLiDAR significantly accelerates the completion time from 30.55 to 5.37 seconds per frame (>5x) on SemanticKITTI and achieves superior performance compared to state-of-the-art 3D LiDAR scene completion models. Our model and code are publicly available on https://github.com/happyw1nd/ScoreLiDAR.

An Zhao, Shengyuan Zhang, Ling Yang et al.

The application of diffusion models in 3D LiDAR scene completion is limited due to diffusion's slow sampling speed. Score distillation accelerates diffusion sampling but with performance degradation, while post-training with direct policy optimization (DPO) boosts performance using preference data. This paper proposes Distillation-DPO, a novel diffusion distillation framework for LiDAR scene completion with preference aligment. First, the student model generates paired completion scenes with different initial noises. Second, using LiDAR scene evaluation metrics as preference, we construct winning and losing sample pairs. Such construction is reasonable, since most LiDAR scene metrics are informative but non-differentiable to be optimized directly. Third, Distillation-DPO optimizes the student model by exploiting the difference in score functions between the teacher and student models on the paired completion scenes. Such procedure is repeated until convergence. Extensive experiments demonstrate that, compared to state-of-the-art LiDAR scene completion diffusion models, Distillation-DPO achieves higher-quality scene completion while accelerating the completion speed by more than 5-fold. Our method is the first to explore adopting preference learning in distillation to the best of our knowledge and provide insights into preference-aligned distillation. Our code is public available on https://github.com/happyw1nd/DistillationDPO.

An Zhao, Piaopiao Yu, Zhe Zhu et al.

3D Gaussian Splatting has exhibited remarkable capabilities in 3D scene reconstruction. However, reconstructing high-quality 3D scenes from motion-blurred images caused by camera motion poses a significant challenge.The performance of existing 3DGS-based deblurring methods are limited due to their inherent mechanisms, such as extreme dependence on the accuracy of camera poses and inability to effectively control erroneous Gaussian primitives densification caused by motion blur. To solve these problems, we introduce a novel framework, Bi-Stage 3D Gaussian Splatting, to accurately reconstruct 3D scenes from motion-blurred images. BSGS contains two stages. First, Camera Pose Refinement roughly optimizes camera poses to reduce motion-induced distortions. Second, with fixed rough camera poses, Global RigidTransformation further corrects motion-induced blur distortions. To alleviate multi-subframe gradient conflicts, we propose a subframe gradient aggregation strategy to optimize both stages. Furthermore, a space-time bi-stage optimization strategy is introduced to dynamically adjust primitive densification thresholds and prevent premature noisy Gaussian generation in blurred regions. Comprehensive experiments verify the effectiveness of our proposed deblurring method and show its superiority over the state of the arts.Our source code is available at https://github.com/wsxujm/bsgs

Ahmed H. Shahin, An Zhao, Alexander C. Whitehead et al.

Survival analysis is a valuable tool for estimating the time until specific events, such as death or cancer recurrence, based on baseline observations. This is particularly useful in healthcare to prognostically predict clinically important events based on patient data. However, existing approaches often have limitations; some focus only on ranking patients by survivability, neglecting to estimate the actual event time, while others treat the problem as a classification task, ignoring the inherent time-ordered structure of the events. Furthermore, the effective utilization of censored samples - training data points where the exact event time is unknown - is essential for improving the predictive accuracy of the model. In this paper, we introduce CenTime, a novel approach to survival analysis that directly estimates the time to event. Our method features an innovative event-conditional censoring mechanism that performs robustly even when uncensored data is scarce. We demonstrate that our approach forms a consistent estimator for the event model parameters, even in the absence of uncensored data. Furthermore, CenTime is easily integrated with deep learning models with no restrictions on batch size or the number of uncensored samples. We compare our approach with standard survival analysis methods, including the Cox proportional-hazard model and DeepHit. Our results indicate that CenTime offers state-of-the-art performance in predicting time-to-death while maintaining comparable ranking performance. Our implementation is publicly available at https://github.com/ahmedhshahin/CenTime.

An Zhao, Mingyu Ding, Zhiwu Lu et al.

Existing few-shot learning (FSL) methods make the implicit assumption that the few target class samples are from the same domain as the source class samples. However, in practice this assumption is often invalid -- the target classes could come from a different domain. This poses an additional challenge of domain adaptation (DA) with few training samples. In this paper, the problem of domain-adaptive few-shot learning (DA-FSL) is tackled, which requires solving FSL and DA in a unified framework. To this end, we propose a novel domain-adversarial prototypical network (DAPN) model. It is designed to address a specific challenge in DA-FSL: the DA objective means that the source and target data distributions need to be aligned, typically through a shared domain-adaptive feature embedding space; but the FSL objective dictates that the target domain per class distribution must be different from that of any source domain class, meaning aligning the distributions across domains may harm the FSL performance. How to achieve global domain distribution alignment whilst maintaining source/target per-class discriminativeness thus becomes the key. Our solution is to explicitly enhance the source/target per-class separation before domain-adaptive feature embedding learning in the DAPN, in order to alleviate the negative effect of domain alignment on FSL. Extensive experiments show that our DAPN outperforms the state-of-the-art FSL and DA models, as well as their naïve combinations. The code is available at https://github.com/dingmyu/DAPN.

An Zhao, Moucheng Xu, Ahmed H. Shahin et al.

Understanding the progression trajectories of diseases is crucial for early diagnosis and effective treatment planning. This is especially vital for life-threatening conditions such as Idiopathic Pulmonary Fibrosis (IPF), a chronic, progressive lung disease with a prognosis comparable to many cancers. Computed tomography (CT) imaging has been established as a reliable diagnostic tool for IPF. Accurately predicting future CT scans of early-stage IPF patients can aid in developing better treatment strategies, thereby improving survival outcomes. In this paper, we propose 4D Vector Quantised Generative Adversarial Networks (4D-VQ-GAN), a model capable of generating realistic CT volumes of IPF patients at any time point. The model is trained using a two-stage approach. In the first stage, a 3D-VQ-GAN is trained to reconstruct CT volumes. In the second stage, a Neural Ordinary Differential Equation (ODE) based temporal model is trained to capture the temporal dynamics of the quantised embeddings generated by the encoder in the first stage. We evaluate different configurations of our model for generating longitudinal CT scans and compare the results against ground truth data, both quantitatively and qualitatively. For validation, we conduct survival analysis using imaging biomarkers derived from generated CT scans and achieve a C-index comparable to that of biomarkers derived from the real CT scans. The survival analysis results demonstrate the potential clinical utility inherent to generated longitudinal CT scans, showing that they can reliably predict survival outcomes.

Tiantian He, Keyue Jiang, An Zhao et al.

The long-term progression of neurodegenerative diseases is commonly conceptualized as a spatiotemporal diffusion process that consists of a graph diffusion process across the structural brain connectome and a localized reaction process within brain regions. However, modeling this progression remains challenging due to 1) the scarcity of longitudinal data obtained through irregular and infrequent subject visits and 2) the complex interplay of pathological mechanisms across brain regions and disease stages, where traditional models assume fixed mechanisms throughout disease progression. To address these limitations, we propose a novel stage-aware Mixture of Experts (MoE) framework that explicitly models how different contributing mechanisms dominate at different disease stages through time-dependent expert weighting.Data-wise, we utilize an iterative dual optimization method to properly estimate the temporal position of individual observations, constructing a co hort-level progression trajectory from irregular snapshots. Model-wise, we enhance the spatial component with an inhomogeneous graph neural diffusion model (IGND) that allows diffusivity to vary based on node states and time, providing more flexible representations of brain networks. We also introduce a localized neural reaction module to capture complex dynamics beyond standard processes.The resulting IGND-MoE model dynamically integrates these components across temporal states, offering a principled way to understand how stage-specific pathological mechanisms contribute to progression. The stage-wise weights yield novel clinical insights that align with literature, suggesting that graph-related processes are more influential at early stages, while other unknown physical processes become dominant later on.

Mingyu Ding, An Zhao, Zhiwu Lu et al.

Automated deception detection (ADD) from real-life videos is a challenging task. It specifically needs to address two problems: (1) Both face and body contain useful cues regarding whether a subject is deceptive. How to effectively fuse the two is thus key to the effectiveness of an ADD model. (2) Real-life deceptive samples are hard to collect; learning with limited training data thus challenges most deep learning based ADD models. In this work, both problems are addressed. Specifically, for face-body multimodal learning, a novel face-focused cross-stream network (FFCSN) is proposed. It differs significantly from the popular two-stream networks in that: (a) face detection is added into the spatial stream to capture the facial expressions explicitly, and (b) correlation learning is performed across the spatial and temporal streams for joint deep feature learning across both face and body. To address the training data scarcity problem, our FFCSN model is trained with both meta learning and adversarial learning. Extensive experiments show that our FFCSN model achieves state-of-the-art results. Further, the proposed FFCSN model as well as its robust training strategy are shown to be generally applicable to other human-centric video analysis tasks such as emotion recognition from user-generated videos.

Zhiwu Lu, Jiechao Guan, Aoxue Li et al.

Zero-shot learning (ZSL) is made possible by learning a projection function between a feature space and a semantic space (e.g.,~an attribute space). Key to ZSL is thus to learn a projection that is robust against the often large domain gap between the seen and unseen class domains. In this work, this is achieved by unseen class data synthesis and robust projection function learning. Specifically, a novel semantic data synthesis strategy is proposed, by which semantic class prototypes (e.g., attribute vectors) are used to simply perturb seen class data for generating unseen class ones. As in any data synthesis/hallucination approach, there are ambiguities and uncertainties on how well the synthesised data can capture the targeted unseen class data distribution. To cope with this, the second contribution of this work is a novel projection learning model termed competitive bidirectional projection learning (BPL) designed to best utilise the ambiguous synthesised data. Specifically, we assume that each synthesised data point can belong to any unseen class; and the most likely two class candidates are exploited to learn a robust projection function in a competitive fashion. As a third contribution, we show that the proposed ZSL model can be easily extended to few-shot learning (FSL) by again exploiting semantic (class prototype guided) feature synthesis and competitive BPL. Extensive experiments show that our model achieves the state-of-the-art results on both problems.

An Zhao, Mingyu Ding, Jiechao Guan et al.

Zero-shot learning (ZSL) aims to recognize unseen object classes without any training samples, which can be regarded as a form of transfer learning from seen classes to unseen ones. This is made possible by learning a projection between a feature space and a semantic space (e.g. attribute space). Key to ZSL is thus to learn a projection function that is robust against the often large domain gap between the seen and unseen classes. In this paper, we propose a novel ZSL model termed domain-invariant projection learning (DIPL). Our model has two novel components: (1) A domain-invariant feature self-reconstruction task is introduced to the seen/unseen class data, resulting in a simple linear formulation that casts ZSL into a min-min optimization problem. Solving the problem is non-trivial, and a novel iterative algorithm is formulated as the solver, with rigorous theoretic algorithm analysis provided. (2) To further align the two domains via the learned projection, shared semantic structure among seen and unseen classes is explored via forming superclasses in the semantic space. Extensive experiments show that our model outperforms the state-of-the-art alternatives by significant margins.