YongKang He

Yongkang He, Siyuan Peng, Mingjin Chen et al.

Accurately predicting anesthetic effects is essential for target-controlled infusion systems. The traditional (PK-PD) models for Bispectral index (BIS) prediction require manual selection of model parameters, which can be challenging in clinical settings. Recently proposed deep learning methods can only capture general trends and may not predict abrupt changes in BIS. To address these issues, we propose a transformer-based method for predicting the depth of anesthesia (DOA) using drug infusions of propofol and remifentanil. Our method employs long short-term memory (LSTM) and gate residual network (GRN) networks to improve the efficiency of feature fusion and applies an attention mechanism to discover the interactions between the drugs. We also use label distribution smoothing and reweighting losses to address data imbalance. Experimental results show that our proposed method outperforms traditional PK-PD models and previous deep learning methods, effectively predicting anesthetic depth under sudden and deep anesthesia conditions.

Yongkang He, Mingjin Chen, Zhijing Yang et al.

This paper seeks to address the dense labeling problems where a significant fraction of the dataset can be pruned without sacrificing much accuracy. We observe that, on standard medical image segmentation benchmarks, the loss gradient norm-based metrics of individual training examples applied in image classification fail to identify the important samples. To address this issue, we propose a data pruning method by taking into consideration the training dynamics on target regions using Dynamic Average Dice (DAD) score. To the best of our knowledge, we are among the first to address the data importance in dense labeling tasks in the field of medical image analysis, making the following contributions: (1) investigating the underlying causes with rigorous empirical analysis, and (2) determining effective data pruning approach in dense labeling problems. Our solution can be used as a strong yet simple baseline to select important examples for medical image segmentation with combined data sources.

Mingjin Chen, Yongkang He, Yongyi Lu et al.

We aim at incorporating explicit shape information into current 3D organ segmentation models. Different from previous works, we formulate shape learning as an in-painting task, which is named Masked Label Mask Modeling (MLM). Through MLM, learnable mask tokens are fed into transformer blocks to complete the label mask of organ. To transfer MLM shape knowledge to target, we further propose a novel shape-aware self-distillation with both in-painting reconstruction loss and pseudo loss. Extensive experiments on five public organ segmentation datasets show consistent improvements over prior arts with at least 1.2 points gain in the Dice score, demonstrating the effectiveness of our method in challenging unsupervised domain adaptation scenarios including: (1) In-domain organ segmentation; (2) Unseen domain segmentation and (3) Unseen organ segmentation. We hope this work will advance shape analysis and geometric learning in medical imaging.

Mingjin Chen, Yongkang He, Yongyi Lu

Abdominal multi-organ segmentation in computed tomography (CT) is crucial for many clinical applications including disease detection and treatment planning. Deep learning methods have shown unprecedented performance in this perspective. However, it is still quite challenging to accurately segment different organs utilizing a single network due to the vague boundaries of organs, the complex background, and the substantially different organ size scales. In this work we used make transformer-based model for training. It was found through previous years' competitions that basically all of the top 5 methods used CNN-based methods, which is likely due to the lack of data volume that prevents transformer-based methods from taking full advantage. The thousands of samples in this competition may enable the transformer-based model to have more excellent results. The results on the public validation set also show that the transformer-based model can achieve an acceptable result and inference time.

Lianlian Liu, YongKang He, Zhaojie Chu et al.

Generating stylized 3D human motion from speech signals presents substantial challenges, primarily due to the intricate and fine-grained relationships among speech signals, individual styles, and the corresponding body movements. Current style encoding approaches either oversimplify stylistic diversity or ignore regional motion style differences (e.g., upper vs. lower body), limiting motion realism. Additionally, motion style should dynamically adapt to changes in speech rhythm and emotion, but existing methods often overlook this. To address these issues, we propose MimicParts, a novel framework designed to enhance stylized motion generation based on part-aware style injection and part-aware denoising network. It divides the body into different regions to encode localized motion styles, enabling the model to capture fine-grained regional differences. Furthermore, our part-aware attention block allows rhythm and emotion cues to guide each body region precisely, ensuring that the generated motion aligns with variations in speech rhythm and emotional state. Experimental results show that our method outperforming existing methods showcasing naturalness and expressive 3D human motion sequences.