Min He

Minghui Wu, Chenxu Zhao, Anyang Su et al.

Understanding of video creativity and content often varies among individuals, with differences in focal points and cognitive levels across different ages, experiences, and genders. There is currently a lack of research in this area, and most existing benchmarks suffer from several drawbacks: 1) a limited number of modalities and answers with restrictive length; 2) the content and scenarios within the videos are excessively monotonous, transmitting allegories and emotions that are overly simplistic. To bridge the gap to real-world applications, we introduce a large-scale Subjective Response Indicators for Advertisement Videos dataset, namely SRI-ADV. Specifically, we collected real changes in Electroencephalographic (EEG) and eye-tracking regions from different demographics while they viewed identical video content. Utilizing this multi-modal dataset, we developed tasks and protocols to analyze and evaluate the extent of cognitive understanding of video content among different users. Along with the dataset, we designed a Hypergraph Multi-modal Large Language Model (HMLLM) to explore the associations among different demographics, video elements, EEG, and eye-tracking indicators. HMLLM could bridge semantic gaps across rich modalities and integrate information beyond different modalities to perform logical reasoning. Extensive experimental evaluations on SRI-ADV and other additional video-based generative performance benchmarks demonstrate the effectiveness of our method. The codes and dataset will be released at https://github.com/mininglamp-MLLM/HMLLM.

Zhen Wang, Zheng Feng, Yanjun Li et al.

Although substantial efforts have been made using graph neural networks (GNNs) for AI-driven drug discovery (AIDD), effective molecular representation learning remains an open challenge, especially in the case of insufficient labeled molecules. Recent studies suggest that big GNN models pre-trained by self-supervised learning on unlabeled datasets enable better transfer performance in downstream molecular property prediction tasks. However, the approaches in these studies require multiple complex self-supervised tasks and large-scale datasets, which are time-consuming, computationally expensive, and difficult to pre-train end-to-end. Here, we design a simple yet effective self-supervised strategy to simultaneously learn local and global information about molecules, and further propose a novel bi-branch masked graph transformer autoencoder (BatmanNet) to learn molecular representations. BatmanNet features two tailored complementary and asymmetric graph autoencoders to reconstruct the missing nodes and edges, respectively, from a masked molecular graph. With this design, BatmanNet can effectively capture the underlying structure and semantic information of molecules, thus improving the performance of molecular representation. BatmanNet achieves state-of-the-art results for multiple drug discovery tasks, including molecular properties prediction, drug-drug interaction, and drug-target interaction, on 13 benchmark datasets, demonstrating its great potential and superiority in molecular representation learning.

Junyu Li, Ye Zhang, Wen Shu et al.

Multiple instance learning (MIL) has been successfully applied for whole slide images (WSIs) analysis in computational pathology, enabling a wide range of prediction tasks from tumor subtyping to inferring genetic mutations and multi-omics biomarkers. However, existing MIL methods predominantly focus on single-task learning, resulting in not only overall low efficiency but also the overlook of inter-task relatedness. To address these issues, we proposed an adapted architecture of Multi-gate Mixture-of-experts with Multi-proxy for Multiple instance learning (M4), and applied this framework for simultaneous prediction of multiple genetic mutations from WSIs. The proposed M4 model has two main innovations: (1) utilizing a mixture of experts with multiple gating strategies for multi-genetic mutation prediction on a single pathological slide; (2) constructing multi-proxy expert network and gate network for comprehensive and effective modeling of pathological image information. Our model achieved significant improvements across five tested TCGA datasets in comparison to current state-of-the-art single-task methods. The code is available at:https://github.com/Bigyehahaha/M4.

Zhongyuang Liu, Min He, Shaonan Yu et al.

Language-guided embodied navigation requires an agent to interpret object-referential instructions, search across multiple rooms, localize the referenced target, and execute reliable motion toward it. Existing systems remain limited in real indoor environments because narrow field-of-view sensing exposes only a partial local scene at each step, often forcing repeated rotations, delaying target discovery, and producing fragmented spatial understanding; meanwhile, directly prompting LLMs with dense 3D maps or exhaustive object lists quickly exceeds the context budget. We present OmniVLN, a zero-shot visual-language navigation framework that couples omnidirectional 3D perception with token-efficient hierarchical reasoning for both aerial and ground robots. OmniVLN fuses a rotating LiDAR and panoramic vision into a hardware-agnostic mapping stack, incrementally constructs a five-layer Dynamic Scene Graph (DSG) from mesh geometry to room- and building-level structure, and stabilizes high-level topology through persistent-homology-based room partitioning and hybrid geometric/VLM relation verification. For navigation, the global DSG is transformed into an agent-centric 3D octant representation with multi-resolution spatial attention prompting, enabling the LLM to progressively filter candidate rooms, infer egocentric orientation, localize target objects, and emit executable navigation primitives while preserving fine local detail and compact long-range memory. Experiments show that the proposed hierarchical interface improves spatial referring accuracy from 77.27\% to 93.18\%, reduces cumulative prompt tokens by up to 61.7\% in cluttered multi-room settings, and improves navigation success by up to 11.68\% over a flat-list baseline. We will release the code and an omnidirectional multimodal dataset to support reproducible research.

Zhengzhao Ma, Xueru Wen, Boxi Cao et al.

Reinforcement Learning from Verifiable Rewards (RLVR) significantly enhances large language models (LLMs) reasoning but severely suffers from calibration degeneration, where models become excessively over-confident in incorrect answers. Previous studies devote to directly incorporating calibration objective into existing optimization target. However, our theoretical analysis demonstrates that there exists a fundamental gradient conflict between the optimization for maximizing policy accuracy and minimizing calibration error. Building on this insight, we propose DCPO, a simple yet effective framework that systematically decouples reasoning and calibration objectives. Extensive experiments demonstrate that our DCPO not only preserves accuracy on par with GRPO but also achieves the best calibration performance and substantially mitigates the over-confidence issue. Our study provides valuable insights and practical solution for more reliable LLM deployment.

Xuwen Zhou, Fangxin Liu, Chao Wang et al.

Speculative decoding accelerates autoregressive generation by letting draft tokens bypass full verification, but conventional frameworks suffer from frequent false rejections, particularly when draft models produce semantically correct but lexically divergent outputs. In this paper, we present Calibrated Speculative Decoding (CSD), a training-free framework that recovers valid tokens discarded by standard verification. Guided by the principle of "Frequency-Guided Candidate Selection and Probability-Guarded Acceptance," CSD incorporates two lightweight modules: Online Correction Memory, which aggregates historical rejections to propose recurring divergence patterns as rescue candidates, and Semantic Consistency Gating, which verifies candidate admissibility using probability ratios instead of exact token matching. Our evaluation across diverse large language models demonstrates that CSD outperforms existing methods, achieving a peak throughput speedup of 2.33x. CSD preserves model accuracy across all tasks while further boosting performance on complex reasoning datasets. These results establish CSD as a highly effective, lightweight solution for practical LLM deployments.

Xinyu Lu, Kaiqi Zhang, Jinglin Yang et al.

Reinforcement Learning with Verifiable Rewards (RLVR) has emerged as a powerful paradigm for enhancing the reasoning capabilities of Large Language Models (LLMs). However, vanilla RLVR suffers from inefficient exploration, particularly when confronting "hard samples" that yield nearzero success rates. In such scenarios, the reliance on sparse outcome rewards typically results in zero-advantage estimates, effectively starving the model of supervision signals despite the high informational value of these instances. To address this, we propose P^2O, a novel framework that synergizes Prompt Optimization with Policy Optimization. P^2O identifies hard samples during training iterations and leverages the GeneticPareto (GEPA) prompt optimization algorithm to evolve prompt templates that guide the model toward discovering successful trajectories. Crucially, unlike traditional prompt engineering methods that rely on input augmentation, P^2O distills the reasoning gains induced by these optimized prompts directly into the model parameters. This mechanism provides denser positive supervision signals for hard samples and accelerates convergence. Extensive experiments demonstrate that P^2O not only achieves superior performance on in-distribution datasets but also exhibits strong generalization, yielding substantial improvements on out-of-distribution benchmarks (+4.7% avg.).

Lina Zhao, Zihao Bian, Qingyue Chen et al.

Focused Ultrasound Ablation Surgery (FUAS) has emerged as a promising non-invasive therapeutic modality, valued for its safety and precision. Nevertheless, its clinical implementation entails intricate tasks such as multimodal image interpretation, personalized dose planning, and real-time intraoperative decision-making processes that demand intelligent assistance to improve efficiency and reliability. We introduce FUAS-Agents, an autonomous agent system that leverages the multimodal understanding and tool-using capabilities of large language models (LLMs). The system was developed using a large-scale, multicenter, multimodal clinical dataset of over 3000 cases from three medical institutions. By integrating patient profiles and MRI data, FUAS-Agents orchestrates a suite of specialized medical AI tools, including segmentation, treatment dose prediction, and clinical guideline retrieval, to generate personalized treatment plans comprising MRI image, dose parameters, and therapeutic strategies. The system also incorporates an internal quality control and reflection mechanism, ensuring consistency and robustness of the outputs. We evaluate the system in a uterine fibroid treatment scenario. Human assessment by four senior FUAS experts indicates that 82.5\%, 82.5\%, 87.5\%, and 97.5\% of the generated plans were rated 4 or above (on a 5-point scale) in terms of completeness, accuracy, fluency, and clinical compliance, respectively. In addition, we have conducted ablation studies to systematically examine the contribution of each component to the overall performance. These results demonstrate the potential of LLM-driven agents in enhancing decision-making across complex clinical workflows, and exemplify a translational paradigm that combines general-purpose models with specialized expert systems to solve practical challenges in vertical healthcare domains.

Yinglong Yan, Jun Yue, Shaobo Xia et al.

Vector extraction retrieves structured vector geometry from raster images, offering high-fidelity representation and broad applicability. Existing methods, however, are usually tailored to a single vector type (e.g., polygons, polylines, line segments), requiring separate models for different structures. This stems from treating instance attributes (category, structure) and geometric attributes (point coordinates, connections) independently, limiting the ability to capture complex structures. Inspired by the human brain's simultaneous use of semantic and spatial interactions in visual perception, we propose UniVector, a unified VE framework that leverages instance-geometry interaction to extract multiple vector types within a single model. UniVector encodes vectors as structured queries containing both instance- and geometry-level information, and iteratively updates them through an interaction module for cross-level context exchange. A dynamic shape constraint further refines global structures and key points. To benchmark multi-structure scenarios, we introduce the Multi-Vector dataset with diverse polygons, polylines, and line segments. Experiments show UniVector sets a new state of the art on both single- and multi-structure VE tasks. Code and dataset will be released at https://github.com/yyyyll0ss/UniVector.

Liming Zhou, Ailing Liu, Hongwei Liu et al.

Root cause localization remain challenging in complex and large-scale microservice architectures. The complex fault propagation among microservices and the high dimensionality of telemetry data, including metrics, logs, and traces, limit the effectiveness of existing root cause analysis (RCA) methods. In this paper, a residual-connection-based RCA method using large language model (LLM), named RC-LLM, is proposed. A residual-like hierarchical fusion structure is designed to integrate multi-source telemetry data, while the contextual reasoning capability of large language models is leveraged to model temporal and cross-microservice causal dependencies. Experimental results on CCF-AIOps microservice datasets demonstrate that RC-LLM achieves strong accuracy and efficiency in root cause analysis.

Cunshi Wang, Yu Zhang, Yuyang Li et al.

The exponential growth of large-scale telescope arrays has boosted time-domain astronomy development but introduced operational bottlenecks, including labor-intensive observation planning, data processing, and real-time decision-making. Here we present the StarWhisper Telescope system, an AI agent framework automating end-to-end astronomical observations for surveys like the Nearby Galaxy Supernovae Survey. By integrating large language models with specialized function calls and modular workflows, StarWhisper Telescope autonomously generates site-specific observation lists, executes real-time image analysis via pipelines, and dynamically triggers follow-up proposals upon transient detection. The system reduces human intervention through automated observation planning, telescope controlling and data processing, while enabling seamless collaboration between amateur and professional astronomers. Deployed across Nearby Galaxy Supernovae Survey's network of 10 amateur telescopes, the StarWhisper Telescope has detected transients with promising response times relative to existing surveys. Furthermore, StarWhisper Telescope's scalable agent architecture provides a blueprint for future facilities like the Global Open Transient Telescope Array, where AI-driven autonomy will be critical for managing 60 telescopes.

Chen Li, Xutan Peng, Shanghang Zhang et al.

Knowledge Base Completion (KBC), which aims at determining the missing relations between entity pairs, has received increasing attention in recent years. Most existing KBC methods focus on either embedding the Knowledge Base (KB) into a specific semantic space or leveraging the joint probability of Random Walks (RWs) on multi-hop paths. Only a few unified models take both semantic and path-related features into consideration with adequacy. In this paper, we propose a novel method to explore the intrinsic relationship between the single relation (i.e. 1-hop path) and multi-hop paths between paired entities. We use Hierarchical Attention Networks (HANs) to select important relations in multi-hop paths and encode them into low-dimensional vectors. By treating relations and multi-hop paths as two different input sources, we use a feature extractor, which is shared by two downstream components (i.e. relation classifier and source discriminator), to capture shared/similar information between them. By joint adversarial training, we encourage our model to extract features from the multi-hop paths which are representative for relation completion. We apply the trained model (except for the source discriminator) to several large-scale KBs for relation completion. Experimental results show that our method outperforms existing path information-based approaches. Since each sub-module of our model can be well interpreted, our model can be applied to a large number of relation learning tasks.