Yi Pan

Ruitao Xie, Limai Jiang, Xiaoxi He et al.

Machine-based brain tumor segmentation can help doctors make better diagnoses. However, the complex structure of brain tumors and expensive pixel-level annotations present challenges for automatic tumor segmentation. In this paper, we propose a counterfactual generation framework that not only achieves exceptional brain tumor segmentation performance without the need for pixel-level annotations, but also provides explainability. Our framework effectively separates class-related features from class-unrelated features of the samples, and generate new samples that preserve identity features while altering class attributes by embedding different class-related features. We perform topological data analysis on the extracted class-related features and obtain a globally explainable manifold, and for each abnormal sample to be segmented, a meaningful normal sample could be effectively generated with the guidance of the rule-based paths designed within the manifold for comparison for identifying the tumor regions. We evaluate our proposed method on two datasets, which demonstrates superior performance of brain tumor segmentation. The code is available at https://github.com/xrt11/tumor-segmentation.

Ruimin Ma, Ruitao Xie, Yanlin Wang et al.

Autism spectrum disorder (ASD) is a highly disabling mental disease that brings significant impairments of social interaction ability to the patients, making early screening and intervention of ASD critical. With the development of the machine learning and neuroimaging technology, extensive research has been conducted on machine classification of ASD based on structural Magnetic Resonance Imaging (s-MRI). However, most studies involve with datasets where participants' age are above 5 and lack interpretability. In this paper, we propose a machine learning method for ASD classification in children with age range from 0.92 to 4.83 years, based on s-MRI features extracted using contrastive variational autoencoder (CVAE). 78 s-MRIs, collected from Shenzhen Children's Hospital, are used for training CVAE, which consists of both ASD-specific feature channel and common shared feature channel. The ASD participants represented by ASD-specific features can be easily discriminated from TC participants represented by the common shared features. In case of degraded predictive accuracy when data size is extremely small, a transfer learning strategy is proposed here as a potential solution. Finally, we conduct neuroanatomical interpretation based on the correlation between s-MRI features extracted from CVAE and surface area of different cortical regions, which discloses potential biomarkers that could help target treatments of ASD in the future.

Ruitao Xie, Jingbang Chen, Limai Jiang et al.

Explainability poses a major challenge to artificial intelligence (AI) techniques. Current studies on explainable AI (XAI) lack the efficiency of extracting global knowledge about the learning task, thus suffer deficiencies such as imprecise saliency, context-aware absence and vague meaning. In this paper, we propose the class association embedding (CAE) approach to address these issues. We employ an encoder-decoder architecture to embed sample features and separate them into class-related and individual-related style vectors simultaneously. Recombining the individual-style code of a given sample with the class-style code of another leads to a synthetic sample with preserved individual characters but changed class assignment, following a cyclic adversarial learning strategy. Class association embedding distills the global class-related features of all instances into a unified domain with well separation between classes. The transition rules between different classes can be then extracted and further employed to individual instances. We then propose an active XAI framework which manipulates the class-style vector of a certain sample along guided paths towards the counter-classes, resulting in a series of counter-example synthetic samples with identical individual characters. Comparing these counterfactual samples with the original ones provides a global, intuitive illustration to the nature of the classification tasks. We adopt the framework on medical image classification tasks, which show that more precise saliency maps with powerful context-aware representation can be achieved compared with existing methods. Moreover, the disease pathology can be directly visualized via traversing the paths in the class-style space.

Ruitao Xie, Jingbang Chen, Limai Jiang et al.

Image classification is a primary task in data analysis where explainable models are crucially demanded in various applications. Although amounts of methods have been proposed to obtain explainable knowledge from the black-box classifiers, these approaches lack the efficiency of extracting global knowledge regarding the classification task, thus is vulnerable to local traps and often leads to poor accuracy. In this study, we propose a generative explanation model that combines the advantages of global and local knowledge for explaining image classifiers. We develop a representation learning method called class association embedding (CAE), which encodes each sample into a pair of separated class-associated and individual codes. Recombining the individual code of a given sample with altered class-associated code leads to a synthetic real-looking sample with preserved individual characters but modified class-associated features and possibly flipped class assignments. A building-block coherency feature extraction algorithm is proposed that efficiently separates class-associated features from individual ones. The extracted feature space forms a low-dimensional manifold that visualizes the classification decision patterns. Explanation on each individual sample can be then achieved in a counter-factual generation manner which continuously modifies the sample in one direction, by shifting its class-associated code along a guided path, until its classification outcome is changed. We compare our method with state-of-the-art ones on explaining image classification tasks in the form of saliency maps, demonstrating that our method achieves higher accuracies. The code is available at https://github.com/xrt11/XAI-CODE.

Yi Pan, Jun-Jie Huang, Zihan Chen et al.

Robust and imperceptible adversarial video attack is challenging due to the spatial and temporal characteristics of videos. The existing video adversarial attack methods mainly take a gradient-based approach and generate adversarial videos with noticeable perturbations. In this paper, we propose a novel Sparse Adversarial Video Attack via Spatio-Temporal Invertible Neural Networks (SVASTIN) to generate adversarial videos through spatio-temporal feature space information exchanging. It consists of a Guided Target Video Learning (GTVL) module to balance the perturbation budget and optimization speed and a Spatio-Temporal Invertible Neural Network (STIN) module to perform spatio-temporal feature space information exchanging between a source video and the target feature tensor learned by GTVL module. Extensive experiments on UCF-101 and Kinetics-400 demonstrate that our proposed SVASTIN can generate adversarial examples with higher imperceptibility than the state-of-the-art methods with the higher fooling rate. Code is available at \href{https://github.com/Brittany-Chen/SVASTIN}{https://github.com/Brittany-Chen/SVASTIN}.

Hao Ma, Zhiqiang Pu, Yi Pan et al. · meta-ai, microsoft-research

Scalability remains a challenge in multi-agent reinforcement learning and is currently under active research. A framework named mean-field reinforcement learning (MFRL) could alleviate the scalability problem by employing the Mean Field Theory to turn a many-agent problem into a two-agent problem. However, this framework lacks the ability to identify essential interactions under nonstationary environments. Causality contains relatively invariant mechanisms behind interactions, though environments are nonstationary. Therefore, we propose an algorithm called causal mean-field Q-learning (CMFQ) to address the scalability problem. CMFQ is ever more robust toward the change of the number of agents though inheriting the compressed representation of MFRL's action-state space. Firstly, we model the causality behind the decision-making process of MFRL into a structural causal model (SCM). Then the essential degree of each interaction is quantified via intervening on the SCM. Furthermore, we design the causality-aware compact representation for behavioral information of agents as the weighted sum of all behavioral information according to their causal effects. We test CMFQ in a mixed cooperative-competitive game and a cooperative game. The result shows that our method has excellent scalability performance in both training in environments containing a large number of agents and testing in environments containing much more agents.

Sunitha Basodi, Krishna Pusuluri, Xueli Xiao et al.

Deep learning models offer superior performance compared to other machine learning techniques for a variety of tasks and domains, but pose their own challenges. In particular, deep learning models require larger training times as the depth of a model increases, and suffer from vanishing gradients. Several solutions address these problems independently, but there have been minimal efforts to identify an integrated solution that improves the performance of a model by addressing vanishing gradients, as well as accelerates the training process to achieve higher performance at larger learning rates. In this work, we intelligently determine which layers of a deep learning model to apply gradient amplification to, using a formulated approach that analyzes gradient fluctuations of layers during training. Detailed experiments are performed for simpler and deeper neural networks using two different intelligent measures and two different thresholds that determine the amplification layers, and a training strategy where gradients are amplified only during certain epochs. Results show that our amplification offers better performance compared to the original models, and achieves accuracy improvement of around 2.5% on CIFAR- 10 and around 4.5% on CIFAR-100 datasets, even when the models are trained with higher learning rates.