Zhaochen Li

CV
h-index31
5papers
66citations
Novelty44%
AI Score44

5 Papers

CVApr 22
Opportunistic Bone-Loss Screening from Routine Knee Radiographs Using a Multi-Task Deep Learning Framework with Sensitivity-Constrained Threshold Optimization

Zhaochen Li, Xinghao Yan, Runni Zhou et al.

Background: Osteoporosis and osteopenia are often undiagnosed until fragility fractures occur. Dual-energy X-ray absorptiometry (DXA) is the reference standard for bone mineral density (BMD) assessment, but access remains limited. Knee radiographs are obtained at high volume for osteoarthritis evaluation and may offer an opportunity for opportunistic bone-loss screening. Objective: To develop and evaluate a multi-task deep learning system for opportunistic bone-loss screening from routine knee radiographs without additional imaging or patient visits. Methods: We developed STR-Net, a multi-task framework for single-channel grayscale knee radiographs. The model includes a shared backbone, global average pooling feature aggregation, a shared neck, and a task-aware representation routing module connected to three task-specific heads: binary screening (Normal vs. Bone Loss), severity sub-classification (Osteopenia vs. Osteoporosis), and weakly coupled T-score regression with optional clinical variables. A sensitivity-constrained threshold optimization strategy (minimum sensitivity >= 0.86) was applied. The dataset included 1,570 knee radiographs, split at the patient level into training (n=1,120), validation (n=226), and test (n=224) sets. Results: On the held-out test set, STR-Net achieved an AUROC of 0.933, sensitivity of 0.904, specificity of 0.773, and AUPRC of 0.956 for binary screening. Severity sub-classification achieved an AUROC of 0.898. The T-score regression branch showed a Pearson correlation of 0.801 with DXA-measured T-scores in a pilot subset (n=31), with MAE of 0.279 and RMSE of 0.347. Conclusions: STR-Net enables single-pass bone-loss screening, severity stratification, and quantitative T-score estimation from routine knee radiographs. Prospective clinical validation is needed before deployment.

CVMar 16
AGE-Net: Spectral--Spatial Fusion and Anatomical Graph Reasoning with Evidential Ordinal Regression for Knee Osteoarthritis Grading

Xiaoyang Li, Runni Zhou, Xinghao Yan et al.

Automated Kellgren--Lawrence (KL) grading from knee radiographs is challenging due to subtle structural changes, long-range anatomical dependencies, and ambiguity near grade boundaries. We propose AGE-Net, a ConvNeXt-based framework that integrates Spectral--Spatial Fusion (SSF), Anatomical Graph Reasoning (AGR), and Differential Refinement (DFR). To capture predictive uncertainty and preserve label ordinality, AGE-Net employs a Normal-Inverse-Gamma (NIG) evidential regression head and a pairwise ordinal ranking constraint. On a knee KL dataset, AGE-Net achieves a quadratic weighted kappa (QWK) of 0.9017 +/- 0.0045 and a mean squared error (MSE) of 0.2349 +/- 0.0028 over three random seeds, outperforming strong CNN baselines and showing consistent gains in ablation studies. We further outline evaluations of uncertainty quality, robustness, and explainability, with additional experimental figures to be included in the full manuscript.

CVFeb 16, 2024
Control Color: Multimodal Diffusion-based Interactive Image Colorization

Zhexin Liang, Zhaochen Li, Shangchen Zhou et al.

Despite the existence of numerous colorization methods, several limitations still exist, such as lack of user interaction, inflexibility in local colorization, unnatural color rendering, insufficient color variation, and color overflow. To solve these issues, we introduce Control Color (CtrlColor), a multi-modal colorization method that leverages the pre-trained Stable Diffusion (SD) model, offering promising capabilities in highly controllable interactive image colorization. While several diffusion-based methods have been proposed, supporting colorization in multiple modalities remains non-trivial. In this study, we aim to tackle both unconditional and conditional image colorization (text prompts, strokes, exemplars) and address color overflow and incorrect color within a unified framework. Specifically, we present an effective way to encode user strokes to enable precise local color manipulation and employ a practical way to constrain the color distribution similar to exemplars. Apart from accepting text prompts as conditions, these designs add versatility to our approach. We also introduce a novel module based on self-attention and a content-guided deformable autoencoder to address the long-standing issues of color overflow and inaccurate coloring. Extensive comparisons show that our model outperforms state-of-the-art image colorization methods both qualitatively and quantitatively.

CVDec 14, 2023
Planning and Rendering: Towards Product Poster Generation with Diffusion Models

Zhaochen Li, Fengheng Li, Wei Feng et al.

Product poster generation significantly optimizes design efficiency and reduces production costs. Prevailing methods predominantly rely on image-inpainting methods to generate clean background images for given products. Subsequently, poster layout generation methods are employed to produce corresponding layout results. However, the background images may not be suitable for accommodating textual content due to their complexity, and the fixed location of products limits the diversity of layout results. To alleviate these issues, we propose a novel product poster generation framework based on diffusion models named P\&R. The P\&R draws inspiration from the workflow of designers in creating posters, which consists of two stages: Planning and Rendering. At the planning stage, we propose a PlanNet to generate the layout of the product and other visual components considering both the appearance features of the product and semantic features of the text, which improves the diversity and rationality of the layouts. At the rendering stage, we propose a RenderNet to generate the background for the product while considering the generated layout, where a spatial fusion module is introduced to fuse the layout of different visual components. To foster the advancement of this field, we propose the first product poster generation dataset PPG30k, comprising 30k exquisite product poster images along with comprehensive image and text annotations. Our method outperforms the state-of-the-art product poster generation methods on PPG30k. The PPG30k will be released soon.

CLOct 15, 2025
Document Intelligence in the Era of Large Language Models: A Survey

Weishi Wang, Hengchang Hu, Zhijie Zhang et al.

Document AI (DAI) has emerged as a vital application area, and is significantly transformed by the advent of large language models (LLMs). While earlier approaches relied on encoder-decoder architectures, decoder-only LLMs have revolutionized DAI, bringing remarkable advancements in understanding and generation. This survey provides a comprehensive overview of DAI's evolution, highlighting current research attempts and future prospects of LLMs in this field. We explore key advancements and challenges in multimodal, multilingual, and retrieval-augmented DAI, while also suggesting future research directions, including agent-based approaches and document-specific foundation models. This paper aims to provide a structured analysis of the state-of-the-art in DAI and its implications for both academic and practical applications.