Junhao Ran

Guanchu Wang, Junhao Ran, Ruixiang Tang et al.

Despite the impressive capabilities of Large Language Models (LLMs) in general medical domains, questions remain about their performance in diagnosing rare diseases. To answer this question, we aim to assess the diagnostic performance of LLMs in rare diseases, and explore methods to enhance their effectiveness in this area. In this work, we introduce a rare disease question-answering (ReDis-QA) dataset to evaluate the performance of LLMs in diagnosing rare diseases. Specifically, we collected 1360 high-quality question-answer pairs within the ReDis-QA dataset, covering 205 rare diseases. Additionally, we annotated meta-data for each question, facilitating the extraction of subsets specific to any given disease and its property. Based on the ReDis-QA dataset, we benchmarked several open-source LLMs, revealing that diagnosing rare diseases remains a significant challenge for these models. To facilitate retrieval augmentation generation for rare disease diagnosis, we collect the first rare diseases corpus (ReCOP), sourced from the National Organization for Rare Disorders (NORD) database. Specifically, we split the report of each rare disease into multiple chunks, each representing a different property of the disease, including their overview, symptoms, causes, effects, related disorders, diagnosis, and standard therapies. This structure ensures that the information within each chunk aligns consistently with a question. Experiment results demonstrate that ReCOP can effectively improve the accuracy of LLMs on the ReDis-QA dataset by an average of 8%. Moreover, it significantly guides LLMs to generate trustworthy answers and explanations that can be traced back to existing literature.

Shi Yu, Chaoyue Tang, Bokai Xu et al.

Retrieval-augmented generation (RAG) is an effective technique that enables large language models (LLMs) to utilize external knowledge sources for generation. However, current RAG systems are solely based on text, rendering it impossible to utilize vision information like layout and images that play crucial roles in real-world multi-modality documents. In this paper, we introduce VisRAG, which tackles this issue by establishing a vision-language model (VLM)-based RAG pipeline. In this pipeline, instead of first parsing the document to obtain text, the document is directly embedded using a VLM as an image and then retrieved to enhance the generation of a VLM. Compared to traditional text-based RAG, VisRAG maximizes the retention and utilization of the data information in the original documents, eliminating the information loss introduced during the parsing process. We collect both open-source and synthetic data to train the retriever in VisRAG and explore a variety of generation methods. Experiments demonstrate that VisRAG outperforms traditional RAG in both the retrieval and generation stages, achieving a 20--40% end-to-end performance gain over traditional text-based RAG pipeline. Further analysis reveals that VisRAG is efficient in utilizing training data and demonstrates strong generalization capability, positioning it as a promising solution for RAG on multi-modality documents. Our code and data are available at https://github.com/openbmb/visrag.

Sheng Li, Yang Sui, Junhao Ran et al.

Video diffusion models have recently enabled high-quality video generation with ViT-based architectures, but remain computationally intensive because generation requires attention computation over long spatiotemporal sequences. Token pruning has proven effective for ViTs and VLMs. However, most prior pruning methods are attention-based and operate per frame, failing to ensure the vital temporal coherence across frames in video generation tasks. In practice, naively adopting attention-only pruning causes noticeable degradation due to worsened background consistency, flickering, and reduced image quality. To address this, we propose TAPE, a training-free Temporal Aware Pruning for Efficient diffusion-based video generation. TAPE (i) applies temporal smoothing to align token-importance across adjacent frames and suppress selection jitter; and (ii) performs token reselection in selected layers to align token pruning with layers' diverse semantic focus and avoid error accumulation in specific areas; it also (iii) adopt a timestep-level budget scheduling that prunes aggressively at early noisy steps and relaxes pruning during fidelity-critical refinement. The experimental results show that TAPE delivers significant speedups while preserving high visual fidelity, outperforming prior token reduction approaches.